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4 Cards in this Set
- Front
- Back
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What happens in rats after transection of facial nerves? How was this seen? What type of reorganization is it most likely because of? |
Reorganization of M1 - Area that formerly represented whiskers is then used for other things (e.g. forelimb or periocular muscle) Seen via electrostimulation of areas Most likely due to functional reorganization rather than anatomical due to the speed of reorganization (fast) |
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What did human fMRI reveal in terms of M1 plasticity? |
Motor activity changes within 3 weeks of training in a two-finger opposition task (thumb & fingers touched in specific sequences) This results in stronger activity and reorganization of M1 |
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Who performed a study on monkeys investigating Hebbian learning? What did they do and find? |
Jackson, 2006 1. Applied microstimulation to M1 neurons that were connected to forearm muscles 2. Researcher paired activation of M1 neurons eliciting activity on a single muscle - Nrec connected to flexor carpi radialis (FCR) to a second neuron - Nstim connected to extensor carpi radialis longus (ECR) using a microchip 3. After a period of learning, stimulation of Nrec resulted in Nstim activation and a consequent change in observed movement in direction and coordinates - Post-stimulation trajectory vector of Nrec is the sum of pre-stimulation trajectory of the two paired muscles (Nstim + Nrec) - Nrec vector slowly changed, while the other two (Nstim and Control) stayed the same |
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How long was needed for conditioning to occur in the Hebbian plasticity experiment ? Why did this most likely occur? |
~ 3 days Reconfiguration of network due to functional changes of synaptic weights (LTP) rather than anatomical changes. |
