Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
5 Cards in this Set
- Front
- Back
|
Small Pox (variola virus): incubation period
|
- 7-17 days
- during incubation, virus replicates in the upper respiratory tract --> primary viremia --> seeds liver and spleen --> secondary viremia --> seeds skin --> classic eruption |
|
|
Small Pox: initial symptoms
|
- fever up to 104
- malaise - severe HA - vomiting - backache |
|
|
Small Pox: rash pattern and distribution
|
- occurs 1-2 days after onset of fever
- begins on face --> spreads to extremities and trunk - initially erythematous macules --> then papules, vesicles, and firm pustules --> crusts form at 8 or 9 days and persist for 3-4 weeks --> as crusts separate, - (majority of lesions are observed on face and extremities, with lesser # on the trunk) - all lesions are in a similar stage of development |
|
|
Varicella: rash pattern and distribution
|
- lesions erupt initially on the trunk and later on the face and extremities
- lesions are erythematous papules that evolve into superficial vesicles, pustules, and crusts - lesions are in varying stages of development - by 7-10 days after infection, all lesions have crusted. |
|
|
Sequele of Varicella vs. Smallpox
|
Varicella: permanent scars are rare, only when lesions had secondary infection
Smallpox: pts are left with significant scars, depigmentation |
