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18 Cards in this Set
- Front
- Back
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What is the most common cause of non-traumatic disability in young adults?
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Multiple Sclerosis
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Active inflammation seen on MRI is 5:1 to _________________.
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# of relapses
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What is seen on MS pts. MR Spectroscopy?
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have much lower NAA
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What does MS diagnosing depend on?
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relies on dissemination of demyelination events in time and space
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Why is the McDonald Criteria the best for diagnosing MS?
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includes the CIS (clinically isolated syndrome)
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What is "Neuromyelitis Optica"?
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Devic's Dx (don't confuse this w/MS)
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What is this? Recurrent transverse myelitis and optic neuritis.
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Devic's Dx (don't confuse this w/MS)
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What has positive NMO Ab in 70% of the pts?
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Devic's Dx (don't confuse this w/MS)
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What would be the tx for Devic's dx?
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Retuxan
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What is the treatment for MS relapses?
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Steroids===Solumedrol (1g/day 3-5 days)
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What are some alternative tx for MS instead of steroids?
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IVIG (.4 g/kg qd 5days), Plasma exchange, ACTH
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What percent of MS pt experience pain?
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70%
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what percent of MS pts experience cognition problems?
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50%
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What are 2 examples of transcutanous peroneal nerve stimulators?
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WalkAide, Bioness
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What are 5 FDA approved drugs for altering the course of MS?
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Copaxone, Rebif, Avonex, Betaseron, Extavia
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What MS drug decreases the influx of T cells and affects the MMPs?
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IFNs
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What are the SE of IFNs?
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Flu-like w/injxn site necrosis
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What MS drug prevents cell adhesion?
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Natalizumab (Tysabri)----PML risk
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