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9 Cards in this Set

  • Front
  • Back
What is the most common primary malignant
CNS tumor in children?
Medulloblastoma
-midline
-blue cell
What is the most common primary malignant
CNS tumor in adults?
Glioblastoma
-ring enhancing
-cross corpus callosum
What is the most common primary site for CNS
metastases?
Lung
What is the most common benign CNS tumor in
children?
Pilocytic astrocytoma
• Which of the following most significantly
increases risk for developing a CNS neoplasm?
▫ Electromagnetic fields
▫ Smoking
▫ Therapeutic radiation
▫ Occupation exposure
▫ Dietary N-nitroso compounds
▫ Trauma
Therapeutic radiation
What is the most common radiation-induced
intracranial tumor?
How long does it take, on average, to develop
after radiation exposure?
Meningioma

8-10 years
Know the enhancement characteristics of the
various grades of diffuse astrocytoma.
Low grade doesn't enhance. High grade enhances.

▫ Grade II: Non-enhancing
▫ Grade III: Patchy enhancement
▫ Grade IV: Ring enhancement
What is the most commonly mutated tumor
suppressor gene in diffuse astrocytomas?
TP53
Genetic mutation in ependymoma?
Deletion of 1p/19q