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19 Cards in this Set
- Front
- Back
topographical organization of ventral horn LMNs
1. flexor muscles 2. extensor muscles 3. paravertebral muscles and proximal limbs 4. distal limbs |
1. posterior
2. anterior 3. medial 4. lateral |
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Golgi tendon organs
1. location 2. measure 3. path of information flow |
1. in tendons near junction with muscle
2. muscle tension 3. GTO > Ib fibers > V horn inhibitory interneuron > inhibits alpha motor neuron > stop contraction of extrafusal fibers |
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Ib fibers
What are they? What do they carry? |
large-diameter, heavily myelinated fibers with high conduction velocity
-carry info from GTOs to SC |
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inverse myotatic reflex (autogenic inhibition)
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interneuron excited by GTO, inhibit alpha motor neurons sypplying the same muscle innervated by the GTO
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Neuromuscular spindles
1. what are they? 2. location 3. what do they measure |
small encapsulated fusiform bundles of specialized myocytes
-located within the muscle among other muscle cells -changes in muscle length, and the rate of those changes |
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2 structural types of intrafusal fibers and 2 phsiologic subtypes
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structural: nuclear bag fibers and nuclear chain fibers
physiologic: static (sensitive to changes in muscle length) and dynamic (sensitive to rate of chang) |
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2 classes of sensory axons supplying equatorial (non-contractile) region of intrafusal fibers
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-group Ia fibers: heavily myelinated, high conduction velocity
-group II fibers: smaller, myelinated fibers, slower conduction |
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group Ia fibers
1. what do they innervate? 2. describe terminal branches 3. myelination and conduction speed |
1. all intrafusal fibers (dynamic and static)
2. primary/annulospiral: wrap around equatorial region of intrafusal fibers in a spiral fashion 3. heavily myelinated; fast conduction |
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group II fibers
1. what do they innervate? 2. describe terminal branches 3. myelination and conduction speed |
1. static intrafusal fibers
2. secondary/flow-spray: clusters of thin, radiating braches near end of nuclear zone 3. small, myelinated; slow conduction |
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innervation of intrafusal muscle fibers (2 types)
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1. dynamic gamma MNs: innervate dynamic nuclear bag fibers
2. static gamma neurons: innervate static nuclear bag and nuclear chain fibers |
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alpha vs. gamma MNs
1. target 2. size 3. conducation speed |
1. extrafusal vs. intravusal
2. larger vs. smaller 3. faster vs. slower |
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isolated muscle prep
1. passive stretch 2. isotonic contaction 3. isometric contraction |
1. stretch applied; no alpha or gamma stimulation
2. constant load; stretch and alpha stimulation applied producing contraction 3. constant length; alpha stimulation applied, but no changes in length |
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Alpha-Gamma coactivation
1. what happens? 2. what does its purpose? |
1. when UMNs signal alpha MNs to contract, parallel signals are sent to gamma MNs causing intrafusal fibers to contract too
2. prevents muscle spindle from becoming slack and inactive |
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Gamma loop
1. what happens? 2. important for... |
1. gamma MNs activated > intrafusal contract > stretches muscle spindle > Ia fibers fire > alpha MN activated > extrafusal contraction
2. maintenance of muscle tone |
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The muscle stretch (myotatic) reflex
1. describe synapse 2. path of impulse |
1. one synapse (monosynaptic) b/n Ia fibers and alpha MN
2. tap tendon > Ia fiber > alpha motor neuron > extrafusal fibers of same muscle |
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reciprocal inhibition of myotatic reflex
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Ia fibers synapse with inhibitory glycinergic interneurons that inhibit alpha MN supplying anatagonist muscles
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Flexor (Withdrawl/Nociceptive) Reflex
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A-delta and C fibers for synapse with...
1. excitatory interneurons that supply ipsi flexor mmm 2. inhibitory interneurons that supply ipsi extensor mm -results in withdrawl of body part from source of injury |
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Crosssed Extension Reflex
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A-delta and C fibers carry nociceptive input to interneurons that project to contralateral ventral horn
1. cause excitation of contralateral extensor mm 2. cause inhibition of contralateral flexor mm |
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Neurotransmitters
1. excitatory interneurons 2. inhibitory interneurons |
1. glutamine
2. glycine |