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76 Cards in this Set

  • Front
  • Back

Neuromuscular Junction

Calcium mediated Ach release, causes action potential

Small motor unit

Slow fatigue, slow twitch, few muscle fibers

Moderate motor unit

slow fatigue, fast twitch, moderate muscle fibers

Large Motor Unit

Fast twitch, fast fatigue, lots of muscle fibers

Musculoskeletal Properties

Speed of contraction, muscle length and Biomechanics affect force production

Sensory Receptors

Cell body is in the dorsal root ganglion, are stimulation specific, intensity coding and sensory adaptation

Proprioception

Awareness of one's own body in space

Joint receptor

Located in joint capsules, fire in response to movement of joint. Minor proprioceptor

Golgi Tendon Organ

Located near muscle/tendon junction, fire in response to active contraction, protects the muscle from tearing

Muscle Spindles

Located in the belly of the muscle, Important for sensory input and motor control. Fires with active and passive stretch

Dorsal Column system

Fast, crosses at brainstem to thalamus then to somatosensory cortex

Anterolateral System

Important for temperature, pain and touch. Located in spinal cord

Spinocerebellar Track

Cerebellum and Brainstem

Pyramid Track

Fast, large diameter, highly myelinated. From primary motor cortex synapse directly to motor neuron pools, crosses in the brainstem

Extrapyramid tracts

Modulatory, from brainstem to cerebellum

Motor neuron pools

Grouped functionally, cell bodies and dendrites. Multiple inputs from motor tracts, sensory neurons and interneurons

Circuitry flow

Sensory receptor -> Sensory Neuron -> Integrating center -> motor neuron -> effector

Stretch Reflex

Monosynaptic (Patellae Reflex)

Flexion Reflex

Finger touches fire, pull hand back

Plantar reflex (babinski sign)

Touching bottom of foot, toes curl (inward for adults, outward for babies) Can show motor neuron lesion if outward as adult since didn't override reflex.

Ocular Reflex

Blink when startled

Vestibulo ocular reflex

Eyes follow head

Tonic Asymmetric reflex

Head turns, same side arm flares out, otherside comes in.

Tonic symmetric reflex

Head curls in, arms curl in

Startle Reflex

When startled, throws back all limbs and head

Righting reflex

When acceleration of head increases, extend neck back to keep head upright

Areas of Cerebral Cortex

Primary motor area, secondary motor area, association areas, basal ganglia and cerebellum

Premotor Area (PMA)

Receives info from cerebellum, externally initiated, sensory driven

Supplementary Motor area (SMA)

Receives info from basal ganglia, internally driven, intention driven

Cingulate Motor area

Motivation/desire, sudden insight, participates in long term memory

Primary Motor Area (M1)

Has fine motor control, Homonculus

Homonculus

Map of the fine motor controls, mainly cortical control. Affects reaching, gait, balance and posture

Cerebellum

Sensory integration, motor adaptation, motor learning

Cerebrocerebellum

Lateral hemisphere, projects to the cortex, Used in planning, precise movements, conscious evaluations of errors

Spinocerebellum

receives Sensory input from body, Compares sensory input to intended movements and adjusts as needed

Vestibulcerebellum

Coordination of eyes and head, balance and posture

Basal Ganglia

Involved in before and during movement, internally generated, movement sequencing, ballistic force generation, sends info to SMA, receives info from frontal and parietal lobes

Brainstem

Automatic movements, many motor tracks that run through it

Tectospinal Tract

Head and eye movement

Reticulospinal Tract

Trunk and proximal limb movements for locomotion and postural control

Vestibulospinal Tract

Position of head and limbs to support posture and maintain balance

Corticospinal Tract

Descending command from Primary Motor Area, individual finger movements

Rubrospinal Tract


Similar to cortiospinal except for finger movements.Limb movements


Thalamus

Relay station for neurons

Corpus Callosum

Transmission between hemispheres

Auditory system

Sound waves deflect hair cells in cochlea opening channels, Signals go through several brainstem centers and thalamus before reaching primary auditory cortex

Vestibular system

Fluid filled semicircular canals, olith organs located inside canal and contain ampulla and capula. When head moves, fluid moves and deflect hair cells. Fires in response to angular and linear accelerations

Visual System

Light sensitive transducers, signal goes through thalamus, NO brainstem centers and then to primary visual cortex

saccades

Controlled by basal ganglia, Ballistic movement, eyes shifting from object to object

Smooth Pursuit

Controlled by Cerebellum, Smooth movement, follow something as it moves

Mangocellular

Ambient vision, goes to dorsal stream, motion vision, mostly unconscious (WHERE)

Pavocellular

Focal vision, goes to ventral stream, object vision, conscious, patterns and shapes. (What)

Advance Information (Visual)

Gain info prior to movement, exproprioceptive, things like shape, size, texture of something

Feedforward (visual)

Anticipating while moving, (Hitting a ball)

Feedback

Response while moving (carrying glass of water)

Electroencephalography

Picks up impulses from brain, great for timing of brain impulses

Positron Emission Tomography (PET)

Indicate activity by glucose uptake. Great spacial but bad timing

Magnetic Resonance Imaging (MRI)

Very structural image, Great spacial but timing is bad. Can look at white matter tracts, uses water uptake to take image.

Transcranial Magnetic Stimulation

Uses magnetic impulses to induce neurons into firing. Can measure how excited or inhibited the brain is.

18 Days (Prenatal development)

Notochord forms from ectoderm in region of primitive streak

20 Days (Prenatal Development)

Neural plate begins to fold upon itself, forming the neural groove and the neural crest becomes distinct

22 Days (Prenatal Development)

Neural plate closes forming the neural tube. Adjacent to the tube is the somites (form skeleton)

24 Days (Prenatal Development)

Neural tube adjacent to somites, becomes spinal cord, neural crest becomes dorsal root ganglion, anterior end of neural plate becomes brain.

Telencephalon

Olfactory lobes, hippocampus and cerebrum

Diencephalon

Retina, epithalamus, thalamus, hypothalamus

Mesencephalon

Midbrain

Metencephalon

Cerebellum, Pons

Myelencephalon

Medulla

100 Days (Prenatal Development)

Cerebral Hemisphere, cerebellum, pons and medulla formed.

Week 9

Recognizable human head, is half of fetus, differential of tissue almost done

Month 5 (Prenatal Development)

Gyri and sulci begin to develop, many of them resent by birth

20-22 Weeks (Prenatal Development)

Reflexes begin to develop

Maturity of brain development

Occipital - 1 year, Parietal and Temporal - 6 Years and frontal 20 years

Parkinson's Disease

Reduction of 70-80% of basal ganglia, reduced dopamine production. Symptoms are bradykinesia, rigidity, Tremor, speech and swallowing difficulty, pain, depression, sleep dysfunction. Use synthetic dopamine, music/environment to trigger movement.

Huntington's Disease

Genetic cause, To much dopamine which results in cell death in basal ganglia. Symptoms Chorea and tics, lack of coordination, unsteady gait, dementia, hyperkinetic disorder.

Cerebellar Ataxia

Progressive, degenerative, genetic disease. Degeneration of cerebellum. Ataxic gait and reaching, poor coordination, difficulty with eye tracking, intention tremor, hypotonia.