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63 Cards in this Set
- Front
- Back
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Acute pulmonary edema
Macroscopic lung is ? |
Lung is distenden and when compressed liquid is eliminated
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Acute pulmonary edema
Microscopic lung alveolar septum? |
dilated capillaries and serum extravasation = septal edema
intralveolar air+serum =alveolar edema |
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Chronic pulmonary congestion
Macroscopic |
congested and fleshy lungs,brown color
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Chronic pulmonary edema
Microscopic characteristics |
brown hemosiderin Macrophages
Thickened alveolar septa (pulmonary fibrosis) |
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Hepatic Congestion
acute and chronic Macro |
Enlarged liver
yellow = hepatic parenchyma red = dilated C.vein sinusoid capillaries |
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Another name for
Chronic Hepatic Congestion |
Nutmeg Liver
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Chronic Hepatic Congestion
Microscopically |
Dilation of central veins and sinusoid capilaries and their fusion with neighbouring cells
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Hepatic prolonged congestion Macroscopic
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On palpation hardening (Induration)
Irregular grey areas of connective tissue, due to regeneration |
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Acute Hepatic Congestion
Microscopically |
Dilation of central veins in hepatic lobules
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Another name for
Prolonged Hepatic Congestion |
Liver cirrhosis
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Prolonged Hepatic Congestion
Microscop |
areas of fibrosis
connective tissue and destroyed hepatocytes in those areas |
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Acute infarction of Kidney
Macroscop |
Infarction area is pale, bulged
surrounded by a red hyperemic ring white anemic infarction |
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Acute infarction of Kidney
Microscop |
area of infarct is pale the narrow rim can be seen,
made by dilated capillaries and extravasated blood+ neutrophils |
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Acute infarction of Kidney
microscopic. what is missing in the affected area |
Nuclei are missing
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Acute infarction of the lung
Macroscopically |
area of infarction is red, triangular
occluded vessel at apex |
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Acute infarction of the lung
Microscopically |
area is red and nuclei are missing
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Mixed Thrombus is formed in
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Living body
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Mixed Thrombus macro
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adherent to the vessel wall
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Mixed Thrombus Microscop
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located into the lumen of vessels
Pink .. platelets Red .. erythrocytes |
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Hyperkeratosis macroscop
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Skin is hardened on palpitation
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Hyperkeratosis microscop
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thickening of stratum corneum
no nuclei in this layer |
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Layers of the skin
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Corneal
Lucidum Granulosum Spinosum Basal |
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Fatty liver (steatosis)
Macro |
enlarged
yellow and soft greasy friable |
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Fatty liver (steatosis)
Microscop |
clear vacuoles (fat) within hepatocytes
Whole surface of lobe is affected |
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Renal amyloidosis
macro |
kidney is enlarged
pale shiny glassy |
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Renal amyloidosis
microscop |
amyloid acumulation in
glomerules extracellular space amyloid in HE = pink In congo dye = its red |
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Fibrinous pericarditis appearance
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Bread and butter
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Fibrinous pericarditis macro
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Villous membrane on the epicardial surface
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Fibrinous pericarditis microscop
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pink fibrin deposits on epicardial surface
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Hepatic abcess macro
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localized cavity pus
necrosis within liver parenchyma |
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Hepatic abcess microscop
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numerous neutrophils
around cavity necrosis can be seen |
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foreign body granuloma
macro |
welldefined palpable nodule
within the breast |
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foreign body granuloma
microscop |
chrystals of cholesterol
and giant multinucleated cell (foreign body giant cells) |
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Tuberculous Lymphadenitis
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lymphnode is increasing in size
(lympadenopathy) yellow white cheese like necrosis (caseous necrosis) |
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foreign body granuloma
macro |
welldefined palpable nodule
within the breast |
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foreign body granuloma
microscop |
chrystals of cholesterol
and giant multinucleated cell (foreign body giant cells) |
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Tuberculous Lymphadenitis
Macro |
lymphnode is increasing in size
(lympadenopathy) yellow white cheese like necrosis (caseous necrosis) |
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Tuberculous lymphadenitis
microscop |
mixed tubercles within the lymphnode
multinucleated langhans cells with horseshoe arrangement of peripheral nuclei |
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mucinous cystadenoma ovary
macro |
ocular cystic spaces
gelatinous fluid rich in glycoprotein encapsulated benign , usually large |
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mucinous cystadenoma ovary
microscop |
walls lined by tall columnar epith
no atypical cells observed |
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mucinous cystadenoma ovar
Immunohistochemistry |
Tumour cells are marked by Cytokeratin
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Fibroadenoma of the breast
Macro |
well circumscribed mobile palpable
young women grayish white nodule s slit like spaces |
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Fibroadenoma of the breast
Microscop |
pericanalicular fibroadenoma
(fibroblasts proliferation) intracanalicular fibroadenoma (prolif fibroblasts compress ducts into clefts) |
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Fibroadenoma of the breast
Immunohistochemistry |
ductalcells are marked by Cytokeratin
fibroblasts by Vimentin |
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Leiomyoma of uterine corpus
Macro |
well defined nodules, multiple
spherical and firm, no capsule bulges above other myometrium white and trabecular |
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Leiomyoma of uterine corpus
microscop |
proliferation of smooth muscle cells
fusiform shape no atypical mitoses present |
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Immunohistochemistry
Leiomyoma of uterine corpus |
tumor cells are marked by Vimentin
and smooth muscle antigen SMA |
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Cavernous hemangioma Liver
Macro |
red - blue
soft spongy mass on section contains venous blood |
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Cavernous hemangioma Liver
Microscop |
proliferation of large vascular spaces
defined by surrounding hepatocytes not encapsulated |
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Cavernous hemangioma Liver
Immunohistochemistry |
tumor cells are marked by cd31 cd34
they are specifik antibodies |
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Invasive squamos cell carcinoma
macro |
a nodular lesion ,
can be ulcerated can present hyperkeratosi usually face skin or lip also on tongue |
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Invasive squamos cell carcinoma
microscop |
in epidermis and dermis
proliferation of atypical cells that resembles spinosum layer tumor cells arranged in clusters polygonal shape large, atypical nuclei |
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Immunohistochemistry
Invasive squamos cell carcinoma |
tumor cells marked by Cytokeratin
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Invasive basal cell carcinoma
macro |
nodular lesion on skin of face
can be ulcerated or erythomatous plaq does not occur on mucos surface |
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Invasive basal cell carcinoma
microscop |
in epidermis and dermis the tumor cells are arranged in small islands
cells resemble those in basal layer small round atypical |
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Immunohistochemistry
Invasive basal cell carcinoma |
tumor cells are marked by Cytokeratin
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where can palisading arrangement
be found |
basal cell carcinoma at the periphery of the cells of the islands
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well differentiated colorectal adenocarcinoma - macro
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polypoid
vegetant ulcerated infiltrative |
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well differentiated colorectal adenocarcinoma - microscop
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prliferation of atypical glands
that infiltrates mucosa, submucosa and muscularis of colon wall |
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Immunohistochemistry
well differentiated colorectal adenocarcinoma |
tumor cells marked by Cytokeratin
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Hodgkins Lymphoma
Nodular Sclerosis - macro |
enlarged lymphnodes
smooth surface cervical and axillay lymph nodes first |
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Hodgkins Lymphoma
Nodular Sclerosis - microscop |
cellular nodules replaces normal
separated by band of collagen. Reed Sternberg cells Hodgkins cells |
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Immunohistochemistry
Hodgkins Lymphoma Nodular Sclerosis |
Reed sternberg cells are marked by
CD15 and CD30 |
