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30 Cards in this Set
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- Back
- 3rd side (hint)
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Acute oophoritis
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purulent inflammation
ascending bacterial infections periovarian inflammation peritonitis, tuboovarian abcess |
pelvic pain
fever vaginal discharge |
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Chronic oophoritis
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ascending infection
recurrent acute oophoritis |
hydrosalpinx
pyosalpinx periovarian adhesions tuboovarian cyst infertility |
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Non neoplastic cysts
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Solitary follicular cyst
Luteal cyst (Corpus Luteum) Polycystic ovarian syndrome multiple follicular cysts Endometriotic cyst (blood filled) Serous epithelial inclusion cysts |
Complication:Non neoplastic cys
ovarian tosion |
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Ovarian tumors classification
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Epithelial (80%)
Sex cord-stromal Germ cell tumors Other tumors |
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Epithelial tumors WHO
Benign and Borderline |
Benign: serous/mucinous cystadenoma
Benign endometrioid cystadenoma Benign brenner Benign clear cell |
Serous/mucinous borderline tumor
Endometrioid borderline tumor |
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Epithelial tumors WHO
Malignant |
Serous/mucinous cystadenoma
Endometrioid adenocarcinoma Transitional cell carcinoma clear cell cystadenocarcinoma |
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Ovarian tumors sex cord-stromal
WHO |
Granulosa cell tumor group
Thecoma-fibroma group Sertoli-leydig cell tumor group Steroid-cell tumors |
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Ovarian-tumor Germ cell tumors
WHO |
Mature teratoma, Immature terat
Dysgerminoma Choriocarcinoma, yolksac tumor Mixed germ cells tumor |
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Other Ovarian tumors WHO
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Lymphomas
Carcinoid tumors |
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Benign epithelial
Serous/mucinous cystadenoma |
women btw 20-45 years age
uni or multi smooth walled cyst serous/mucinous content usually without necrosis uni or bilateral |
micro: papillary adenoma with cystic dilatation
Complica: rupture,torsion, superinfection,malignant transf |
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Benign epithelial
Brenner tumor |
solid tumors can contain cystic areas. 15% bilateral.
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micro: sheets of transitional cells and microcysts
1% malignant transf |
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Benign epithelial
endometrioid cystadenoma |
usually unilateral tumors that arise from ovarian endometrioid islets
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Borderline epithelial tumor
Only definition |
atypical cells proliferation
not crossing basement membran |
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Borderline epithelial tumor
Serous/mucinous borderline |
50-60% serous 40-50% mucinou
cystic tumor with filled cavities intracystic papillary projections uni or bilateral tumor 40% |
micro: serous = papillae lined
with stratified cuboidal or columnar. mucinous = papillae lined with stratified intestinal type epithelium with nuclear atypia |
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Borderline epithelial tumor
Serous/mucinous borderline Only complications |
non-invasive or invasive peritoneal implants
invasve implants= metastazing cystadenocarcinoma |
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Borderline epithelial tumor
Endometrioid borderline |
proliferation of atypical endometrium type glands, without stromal invasion
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Malignant epithelial tumor
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oral contraceptive pills and pregnancy are protective
RF: BRCA1/BRCA2 mutations MMR gene mutations, microsatellite instability. metastases into= lymph nodes peritoneal cavity, lung,liver,pleura |
back/abdominal pain
urinary symptoms, weight loss palpation or ultrasound examination = mass |
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Malignant epithelial
serous/mucinous cystadenocarcinoma |
primary tumor or malignant trans from cystadenoma/borderline
occurs mainly 7th decade life solid or cystic with hemorrhages and necrosis |
micro: glandular,papillary or solid
prognostic: 1 grade G1 G2 G3 2 stage FIGO/pTNM |
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serous/mucinous cystadenocarcinoma
Stages |
1, tumor limited to ovaries
2, invasion of other pelvic struct 3, peritoneal metastases outside 4, distant metastases |
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Malignant epithelial endometriod adenocarcinoma
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malignant variant of
endometriod cystadenoma 20 % bilateral solid tumor , uni or bilateral |
micro: similar to endometrioid carcinoma of the uterine corpus
papillae + atypical glands |
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Epithelial secondary tumors
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gastric signet ring cell carcinom
bilateral ovarian metastases appendiceal, colorectal carcinoma breast carcinoma, cervical canc pancreatic carcinoma |
others: lung cancer, lymphoma,melanoma
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Ovarian SS tumors
Definition + Clinical |
tumors from ovarian stromal and sex-cord cells surrounding ovarian follicles, mostly benign.
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tumor cells secretes estrogen,progesterone androgen
uterine bleeding, endometrial hyperplasia |
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Ovarian SS tumors
Granulosa cell tumor group |
tumors arising from granulosa
postmenopausal most affected Adult type 20% malignant Juvenile type 5% |
unilateral tumor
hemorrhages and necrotic areas adult micro Call Exner bodies clini: elevated serum inhibin |
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Ovarian SS tumors
Thecoma |
benign tumor from postmenopausal thecal cells
secretes estrogen |
unilateral solid yellow grey
micro: spindle cells lipids inside |
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Ovarian SS tumors
Fibroma |
Meigs syndrome =
ovarian fibroma + ascites + hydrothorax |
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Ovarian SS tumors
Sertoli-Leydig cell tumor group |
uncommon ovarian tumor
occurs in young women 20-30 unilateral secretes androgen well moderate or poorly differentiated |
micro:
testicular type structure |
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Germ cell tumors
definition |
benign or malignant
arise from germ cells mainly affects children |
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Germ cell tumors
Teratoma |
mature teratoma
adult type tissue all 3 layers endoderm mesoderm ectoderm solid or cystic |
struma ovarii
composed of thyroid tissue asymptomatic or hyperthyroidi |
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Germ cell tumors
Teratoma 2 |
immature teratoma
potentially malignant neural and mesenchymal tissu |
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Germ cell tumors
nomination |
teratoma
dysgerminoma choriocarcinoma yolksac tumor other germ cell tumors |
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