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25 Cards in this Set
- Front
- Back
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what is in cytoplasm of granular cell tumor
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secondary lysosomes
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cause of renal artery thrombus formation and infarct
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renal infarcts are generally rare and tend to be due to thromboembolism from afib with clot formation in the left atrium/appendage; complete renal infarct generally occurs with aorta disruption (trauma or surgery on aorta)
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warthin's tumor is strongly associated with what clinically
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smoking
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what is the most common parotid gland tumor
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pleomorphic adenoma
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in what gland will Warthin's tumors be most likely found
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parotid
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is Warthin's tumor neoplastic? if so, what component
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both the epithelial and lymphatic components to the Warthin's tumor have been shown to be polyclonal; lymphomas can occur in association with Warthin's but are not thought to be a transformation of the lymphatic component of the Warthin tumor persay
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most common cause of nephrotic syndrome in adults
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FSGS
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cause of most membranous GN
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idiopathic/primary - 85%
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pathogenesis of membranous GN
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immune complex - formed either in situ against the glomerular BM or from systemic circulation and deposited at glomeruli
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are immune complexes in membranous GN subendothelial or subepithelial
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subepithelial
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what does IF look like for membranous GN
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granular deposits of immunoglobulins and complement
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most common parotid tumor/most common salivary gland tumor
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pleomorphic adenoma
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what is antithesis to the notion that pleomorphic adenomas are benign
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they are aneuploid, can recur after resection, invades normal adjacent tissue and distant metastases have been reported after long (+10 years) time intervals
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most common lymphomas in thyroid
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Diffuse large B-cell lymphoma with marginal zone
Diffuse large B-cell lymphoma without marginal zone Marginal zone В-cell lymphoma of mucosa-associated lymphoid tissue (MALT) Follicular lymphoma |
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what clinical condition are thymomas found in association (25%ish of the time)
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myesthenia gravis
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syndromic associations with ganglioneuromas
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unknown
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most common cause of death from parasite, and second most common...
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1. malaria
2. visceral leishmaniasis |
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signs/sx of visceral leishmaniasis
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fever, weight loss, mucosal ulcers, fatigue, anemia, and substantial swelling of the liver and spleen.
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name three viruses associated with De Quervain's thyroiditis
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- coxsackie
- adenovirus - mummps |
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where is histoplasmosis found
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ohio river valley (tennessee, kentucky, w. virginia, etc)
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definition of dimorphic fungi
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Slow growing fungi that grow as molds at 25-30° and yeast at 35-37° (human body temperature)
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examples of dimorphic fungi (6)
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•Sporothrix schenckii
•Histoplasma capsulatum •Blastomyces dermatitidis •Paracoccidioides brasiliensis •Coccidioides immitis •Penicillium marneffei |
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histoplasma - size and budding shape, location
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narrow base, single bud
3-5 um extracellular or within macs |
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sx of carcinoid crisis
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may include intense flushing, diarrhea, abdominal pain, tachycardia, hypertension or hypotension, altered mental status
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cause of malakoplakia
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defects in phagocytic or degradative functions of histiocytes in response to gram negative coliforms (E. coli or Proteus) that results in chronic inflammatory state, followed by intracellular deposition of iron and calcium (known as Michaelis-Gutmann bodies)
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