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17 Cards in this Set
- Front
- Back
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What are the adverse effects of ASA?
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GI toxicity (consider using EC ASA)
Bleeding: GI, ICH, gingival, bruise easily |
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What are the adverse effects of Clopidogrel (Plavix)?
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interacts w/ PPIs
GI: n/v, dyspespsia, abdominal pain Bleeding: epistaxis, GI Transient liver enzyme elevations TTP (rare) |
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What are the contraindications of Clopidogrel (Plavix)?
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active bleeding and ICH
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What are the adverse effects of Prasugrel (Effient)?
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GI: n/v, diarrhea
Bleeding: GI, intolerable bleeding TTP |
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What are the adverse effects of Ticagrelor (Brilinta)?
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Bleeding
Dyspnea Ventricular pauses Increase in serum uric acid Increase SCr |
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Contraindications of Ticagrelor (Brilinta)?
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Active bleeding
ICH Hepatic impairment When using w/ ASA, ASA dose must be <100mg |
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What are the adverse effects of Abciximab/Eptifibatide?
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Bleeding
Immune-mediated thromocytopenia (greater w/ abciximab) |
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What are the contraindications of Abciximab/Eptifibatide?
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Active bleeding
Thrombocytopenia Prior stroke Eptifibatide contraindicated in renal dialysis |
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What are the adverse effects of Enoxaparin (Lovenox)?
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renally cleared (reduce dose by 50% if CrCl <30)
Bleeding Injection site reactions Thrombocytopenia |
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What are the adverse effects of Fondaparinux (Arixtra)?
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Bleeding
Thrombocytopenia Fever Nausea Anemia |
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What are the contraindications of Fondaparinux (Arixtra)?
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Do not use if CrCl <30
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What are the adverse effects of Bilvalirudin?
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Bleeding
Hypotension Pain Nausea HA Reduce dose for CrCl <30 |
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What are the adverse effects of Fibrinolytics?
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Bleeding (GI)
ICH Injection site reaction |
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What are the contraindications of Nitroglycerin?
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SBP < 90 > 30 below baseline
Extreme bradycardia Concurrent use w/ phosphodiesterase 5 inhibitors |
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What are the adverse effects of Morphine?
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Hypotension
Respiratory distress |
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How should you monitor UFH?
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aPTT, Hgb/Hct (q 24-48 hrs)
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How should you monitor LMWH and Fondaparinux?
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Hgb/Hct, platelets
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