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28 Cards in this Set
- Front
- Back
What are the general considerations for mood stabilizers?
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- Kindling
- Sedation at first - Toxicity |
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Name 6 mood stabilizers
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- Lithium
- Tegretol - Depakote - Neurontin - Topamax - Lamictal |
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What are the side effects of Lithium?
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- Metallic taste in mouth
- GI upset - Fine temors - Weight gain |
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What is the therapeutic range for Lithium?
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0.5- 1.2 mEg/L
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Moderate toxicity is considered above what level for Lithium? What would you see in a patient with this?
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> 1.5
- increased GI upset, confusion, ataxia, tinnitus |
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Severe toxicity is considered above what level for Lithium? What would you see in a patient with this?
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>2.5
- ataxia, seizures, coma, death |
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Can a patient have normal levels of Lithium and still be toxic?
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Yes
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What would cause an increase in Lithium levels?
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- Low sodium in body
- Sweating - Dehydration - Alcohol intake, high |
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What would cause a decrease in Lithium levels?
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- Increased salt, SSRIs, channel blockers
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True or False
Lithium and salt have an inverse relationship. |
True
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What do you teach a patient that is on Lithium?
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- Adequate hydration
- Normal salt intake - S/S of toxicity - Importance of getting level drawn q 2 months |
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How does Tegretol work?
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Inhances GABA
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What are the common side effects of Tegretol?
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- Sedation
- GI upset - Dizziness |
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What do you need a baseline of when giving Tegretol and Depakote?
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Liver function test
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What is the adverse effect of Tegretol?
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Agranulocytosis
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True or False
Tegretol and Depakote are not helpful in patients with rapid cycling? |
False, they are very helpful in patients with rapid cycling
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What is the therapeutic range for Tegretol? What would be some s/s of toxicity?
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- 4-12 ug/mL
- Ataxia and diplopia |
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How does Depakote work?
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Slows the brain's conductivity which in turn stabilizes mood.
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What is the therapeutic range for Depakote?
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50- 100 ug/mL
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What are common side effects for Depakote?
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- GI upset
- Anorexia - Dyspepsia - Dizziness - Weight gain |
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What are adverse reactions to Depakote?
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- Hair loss
- Leukopenia - Thrombocytopenia |
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What levels need to be monitored with Depakote?
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Liver enyzmes q 6-12 months
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Neurotin has similar side effects to?
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Lithium
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What main side effect of Topamax differs from the other drugs?
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Weight loss
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Neurotin is helpful with?
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Anxiety and agitation accompanying BMD
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Lamictal is often used in what treatment for BMD?
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Refractory
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What is the adverse reaction of Lamictal? What would you monitor for?
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- Stevens Johnson Syndrome
- Rash |
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How are mood stabilizers different from antipsychotics?
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- Levels are monitored with mood stabilizers
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