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54 Cards in this Set
- Front
- Back
Define mood
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Description of one's internal emotional state
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What is another name for mood disorder?
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Affective disorder
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What is the difference between a mood episode and mood disorder?
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Mood episode are distinct periods of time when abnormal mood is present; mood disorder are patterns of mood episodes
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What are the types of mood episodes?
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1) Major depressive
2) Manic 3) Hypomanic 4) Mixed episode |
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What are the types of mood disorders?
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1) Major depressive disorder
2) Bipolar I & II disorder 3) Dysthymic disorder 4) Cyclothymic disorder |
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What are the DSM-IV criteria to be a major depressive episode?
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Must have at least 5 of the following during the same 2 week period...(must include anhedonia or depressed mood)
SIG E CAPS D - depressed mood S - sleep disturbances I - interest (anhedonia) G - guilt or worthlessness E - energy or fatigue C - concentration, can't think A - appetite up or down P - psychomotor agitation or retardation S - suicidal ideation *must cause social or occupational impairment |
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What are the DSM-IV criteria to be a manic episode?
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Must have at least 3 of the following for at least 1 week...
DIG FAST D - distractability I - insomnia G - grandiosity F - flight of ideas A - activity/agitation increased S - speech pressured T - thoughtlessness *must cause social or occupational impairment |
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What is a manic episode?
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A condition characterized by elevated or irritable (easily annoyed) mood lasting at least 1 week
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Is a manic episode a psychiatric emergency? Why?
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Yes because severely impaired judgment makes patient dangerous to self and others
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What is a mixed episode?
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Episode that meets the criteria of both manic and major depressive episode for at least 1 week
*psychiatric emergency |
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What is the predominant mood in patients with mixed episodes?
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Irritable mood
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Does lithium work well for mixed episodes?
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Patients with mixed episodes have a poorer response to lithium; anticonvulsants may help
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What is a hypomanic episode?
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Condition characterized by period of elevated or irritable mood; lower of degree of impact on functioning than mania
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What is the difference between a manic and hypomanic episode?
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Mania - causes severe impairment in social/occupational functioning, may require hospitalization, may have psychotic symptoms
Hypomania - no marked impairment in social/occupational functioning, no hospitalization, no psychotic features |
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What is the DSM-IV criteria for major depressive disorder (MDD)?
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At least 1 major depressive episode and no history of manic/hypomanic episode
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What is seasonal affective disorder?
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Subtype of MDD in which major depressive episodes occur only during winter months (fewer daylight hours)
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What is the treatment for seasonal affective disorder?
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Light therapy
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What are the sleep problems associated with MDD?
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1) Multiple awakenings
2) Hard to fall asleep, early morning awakenings 3) Hypersomnia 4) REM affected |
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What is the triad for seasonal affective disorder?
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1) Irritability
2) Hypersomnia 3) Carbohydrate drawing - crave sweets and starchy food |
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How is serotonin related to depression? How can this be used to treat depression?
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Decreased brain levels of serotonin and 5-HIAA (hydroxyindolacetic acid) are found in depressed patients
Drugs that increase the availability of serotonin, NE and dopamine alleviate the symptoms of depression |
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What are other neuroendocrine abnormalities that are associated with depression?
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1) high cortisol
2) thyroid disorders |
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What psychosocial life event is associated with MDD?
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Loss of a parent before age 11
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Is there a genetic component to depression?
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1st degree relatives are 2-3x more likely to have MDD
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Can MDD be associated with psychotic features?
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Yes, hallucinations or delusions
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What are the different treatment modalities of MDD?
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1) Hospitalization
2) Pharmacotherapy 3) Psychotherapy 4) ECT |
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When is hospitalization indicated for MDD?
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If patient at risk for suicide, homicide or unable to care for self
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What is the difference btwn all of the antidepressant medications?
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All are equally effective but differ in side effect profile; medications take 4 to 8 weeks to work
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Describe SSRI's
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Selective serotonin reuptake inhibitor - safe, well tolerated, mild side effects; main one is sexual dysfunction
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Describe TCA's
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Tricyclic antidepressants - overdose is lethal, side effects include anticholinergic effects and can aggravate prolonged QT syndrome
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Describe MAOIs
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Monoamine oxidase inhibitors, useful for refractory depression
*risk of hypertensive crisis when used with tyramine-rich foods (wine, cheese) *risk of serotonin syndrome when used in combination with SSRIs; triad of cognitive, autonomic, and somatic effects |
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Describe stimulants for treating MDD?
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For refractory patients, action is rapid, potential for dependence limits its use
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Describe ECT for treating MDD?
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Electroconvulsive therapy is indicated if patient is unresponsive to pharmacotherapy or patient cannot tolerate pharmacotherapy or rapid reduction of symptoms is desired
*Retrograde amnesia is a common side effect, which usually disappears within 6 months |
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Describe serotonin syndrome.
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1) Autonomic instability
2) Hyperthermia 3) Seizures autonomic, cognitive, somatic |
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What type of patients may not be able to tolerate the side effects of antidepressant medications?
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Elderly and pregnant woman
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What are the unique types of depressive disorders?
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1) Melancholic
2) Atypical 3) Catatonic 4) Psychotic |
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Describe melancholic MDD
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Anhedonia, early morning awakenings, psychomotor disturbance, excessive guilt, anorexia
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Describe atypical MDD
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Hypersomnia, hyperphagia, reacive mood, hypersensitivity to interpersonal rejection
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Describe catatonic MDD
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Catalepsy (immobility), purposeless motor activity, extreme negativism, bizarre postures, echolalia
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Describe psychotic MDD
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Characterized by the presence of delusions or hallucinations
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What kind of drug is effective in treating atypical MDD?
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MAOIs
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How do you treat catatonic MDD?
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With both antidepressants and antipsychotics
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What is the DSM-IV criteria for bipolar I disorder?
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Occurence of one manic or mixed episode; between manic episodes there may be other mood episodes but none are required for diagnosis
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Can psychotic features be associated with bipolar I disorder?
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Yes, always include bipolar I disorder as part of the differential in a psychotic patient
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What pharmacotherapy is out there for treatment of bipolar disorder?
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1) Lithium - mood stabilizier
2) Anticonvulsants - carbamazepine and valproic acid 3) Atypical antipsychotic - olanzapine |
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What are other treatment modalities for bipolar disorder?
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Psychotherapy and ECT
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What is rapid cycling?
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Defined by the occurrence of 4 or more mood episodes in 1 year (major depressive, manic, mixed, etc)
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What are the side effects of lithium?
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A whole list
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What is the DSM-IV criteria for bipolar II disorder?
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History of major depressive episode and at least one hypomanic episode
*if there has been a full manic episode even in the past, then the diagnosis is not bipolar II disorder, but bipolar I |
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What is the DSM-IV criteria for dysthymic disorder?
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1) Depressed mood for the majority of the time of most days for at least 2 years
2) C - concentration poor H - hopelessness A - appetite up or down S - sleep up or down E - energy S - self-esteem *person has not been without the above symptoms for > 2 months at a time; NEVER had a manic or hypomanic episode (would be bipolar disorder) |
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Define double depression?
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Patients with MDD with dysthymic disorder during residual periods
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Can you have psychotic features with dysthymia?
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Delusions or hallucinations are never in patients with dysthymia; consider another diagnosis
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What is the mneumonic of dysthymic disorder?
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2 years of depression
2 listed criteria Never asymptomatic for > 2 months |
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What is the DSM-IV criteria for cyclothymic disorder?
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Numerous periods with hypomanic symptoms and periods of depressive symptoms for at least 2 years, never symptom free for > 2 months during those 2 years
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What personality disorder is associated with cyclothymic disorder?
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Borderline personality disorder
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