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18 Cards in this Set
- Front
- Back
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Of what system are SSRIs an inhibitor? What does this affect?
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1A2; theophylline dosages must be reduced
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What interaction does smoking have with SSRIs?
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Smoking induces 1A2; need more SSRIs
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Which 2 SSRIs are 2D6 inhibitors? What else can they do?
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Fluoxetine & paroxetine; increase plasma levels of TCAs
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Therapeutic level for lithium?
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0.5-1.2 mEq/l
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Other labs for lithium?
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TSH & renal func
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Depakote (divalproex sodium) therapeutic level?
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50-150
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Labs before starting carbamazapine & depakote?
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liver func & CBC
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Atypicals metabolized by 3A4 include :
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clozapine, quetiapine and ziprasidone (Geodon)
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3A4 Inhibitors & inducers:
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Inhibitors: ketoconazole, protease inhibitors, erythromycin
Inducer: carbamazapine |
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Atypicals metabolized by 1A2 enzymes include:
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Clozril & Zyprexa
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1A2 Inhibitors & inducers:
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fluvoxamine
cigarettes |
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Atypicals metabolized by 2D6 include :
Inhibitors (usually not clinically sig) |
risperidone, clozapine and olanzapine
Prozac & Paxil |
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Elevated temperature, changes in level of consciousness, leukocytosis, elevated creatinine phosphokinase, elevated liver enzymes or myoglobinuria indicate:
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NMS
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DA antagonist used for NMS?
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Dantrolene
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Increased ventricle size and abnormalities in frontal cortex, temporal & occipital areas are assoc w/:
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anxiety DOs
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Organic cuases for panic DO Sx?
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Hypoglycemia, pheochromocytoma, & hyperthyroidism
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TCAs used for Panic DO? Tests needed?
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Imipramine and clomipramine
EKG prior to rx |
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Tests to evaluate for OCD? Therapy?
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YBOCS & FOCI
Exposure and Response-Prevention |
