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9 Cards in this Set
- Front
- Back
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Adalimumab |
1. Anti-TNF alpha 2. 40mg subcut every 2 weeks 3. Can be used with MTX or as monotherapy |
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Infliximab |
1. Anti-TNF alpha 2. 3mg/kg week 0, 2, 6, then every 8 weeks 3. SHOULD be given with MTX ADR - mild infusion reactions eg headache urticaria |
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Etanercerpt |
1. Anti-TNF 2. 25mg twice weekly or 50mg once weekly subcut 3 Can be used with MTX or as monotherapy |
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Rituximab |
1. Causes depletion of peripheral B cells (CD20...) 2. two IV infusions, two weeks apart. Not to be given more frequently than 6 months. 3. Should be given with MTX Infusion-related reactions - redness, rash, swelling, itching, bruising. |
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Abatacept |
1. Blocks full activation of T cells (CTLA4 - IgG1 ADCC) 2. Loading dose IV every 2 weeks for 3 doses. Followed by IV infusion every 4 weeks OR subcut every week. Dose by body weight. 3. Should be used with methotrexate |
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Anakinra |
1. IL-1R Antagonist 2. Daily subcut. NOT COMMONLY USED - only when used in a controlled long-term clinical study 3. |
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Tocilizumab |
1. IL-6R antagonist 2. Monthly IV infusion 3. Should be used with MTX |
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Certolizumab pegol |
1. Pegylated portion of Fab domain of anti-TNF alpha 2. 3. Can be used with MTX or as monotherapy |
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Golimumab |
1. Human fab, TNF inhibitor 2. 3. Should be used with MTX |
