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4 Cards in this Set
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- Back
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How might large quantities of the immunoglobulin be produced?
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By a single plasma cell which can be obtained by fusing the cell with a tumor cell, producing an antibody factory.
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By fusing a plasma cell with a tumor cell, how might this be done in practice?
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Animals are immunized with a particular antigen or cell preparation.
The animal is then humanely sacrificed and the antibody producing cells (plasma cells)are extracted from their spleens and fused to myeloma cells. |
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What are myeloma?
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Myelomas are B lymphocyte tumors that readily fuse with plasma cells to form antibody producing hybridomas, which grow and reproduce very well.
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What is then done?
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The fused cells are separated and each starts a clone of cells descended from a single cell.
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