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25 Cards in this Set
- Front
- Back
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Ipilimumab
a.) indication b.) target c.) ADR |
a.) melanoma
b.) CTLA-4 c.) n/a |
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Brentuximab vedotin
a.) indication b.) target c.) ADR |
a.) Hodgkin lymphoma
b.) CD30 c.) PML |
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Canakinumab
a.) indication b.) target c.) ADR |
a.) CAPS (cryopryin-associated periodic syndromes
b.) IL-1B c.) n/a |
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Belimumab
a.) indication b.) target c.) ADR |
a.) SLE
b.) BLyS c.) n/a |
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Palivizumab
a.) indication b.) target c.) ADR |
a.) RSV
b.) F-glycoprotein c.) n/a |
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Omalizumab
a.) indication b.) target c.) ADR |
a.) asthma
b.) human IgE c.) anaphylaxis |
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Ranibizumab
a.) indication b.) target c.) ADR (3) |
a.) macular degeneration
b.) VEGF c.) eye infections, increased pressure, perforation of optic nerve |
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Aflibercept
a.) indication b.) target c.) ADR (2) |
a.) macular degeneration/ macular edema
b.) VEGF-A and PIGF c.) increase intraocular pressure, impaired fertility |
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Eculizumab
a.) indication b.) target c.) ADR |
a.) paroxysmal nocturnal hemoglobinuria
b.) complement protein C5 c.) risk of meningitis |
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Denosumab
a.) indication b.) target c.) ADR |
a.) bones stuff: osteoporosis, bone cancer from solid tumors, or bone loss from any cancer
b.) RANKL c.) n/a |
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Black box warning for fungal infections
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FUNGUS CHASER
Cimzia Humira Actemra Simponi Enbrel Remicaide |
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Which drugs cause PML? (5)
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1.) Tysabri
2.) Rituximab 3.) Obinutuzumab 4.) Brentuxumab vendotin 5.) Infliximab |
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Tysabri ADRs (2)
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1.) PML
2.) Liver damage |
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RA drugs
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RA ROACHES
Remicaide Orencia Actemra Cimzia Humira Enbrel Simponi |
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Crohn's disease drugs
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Crohn - CRH-T
Cimzia Remicaide Humira Tysabri |
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Psoriasis/ psoriatic arthritis
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Psoriasis R-sesh
Remicade Stelera Enbrel Simponi Humira |
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Orencia target
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CD80 & CD86
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Actemra target
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IL-6 antagonist
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Remicaide target
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TNF blocker
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Enbrel target
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TNF blocker
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Humira target
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TNF blocker
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Cimzia target
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TNF blocker
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Simponi target
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TNF blocker
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Zenapax indications (2)
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1.) MS
2.) birdshot chorioretinopathy |
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Birdshot chorioretinopathy
a.) what is it? b.) treatment |
a.) rare eye inflammation. First the uvuea, then the choird and retina. Leads to many vision problems like macular edema. Associated with HLA (human leukocyte antigen haplotype)- A29
b.) zenapax, which is currently not on the market |
