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13 Cards in this Set

  • Front
  • Back
What four questions need to be asked to determine duration and onset of monoarthritis?
Over/ Under 6 week?
Previous episodes?
Rapidly/ slowly worse?
Circumstances of onset?
In the PMH, what factors are commonly associated with gout/ other crystals?
HTN
Renal failure
Hypercholesterolaemia
Dehydration
In the PMH, what factors are associated with a predisposition to infection?
Chronic/ Systemic disease or Malignancy
Joint replacement
Recent infection
Name 5 systemic features
Fever
Malaise
Weight loss
Anorexia
Infections (Skin/respiratory/urinary)
Give 8 differentials of a swollen knee
1. Septic arthritis
2. Crystal synovitis (Gout/ pseuodgout)
3. Trauma (Cartliage/ Ligamentous)
4. Haemarthrosis
5. Chronic Inflammatory (OA/ TB arthritis/ Psoriatic arthritis)
6. Aseptic necrosis
7. Sero- negative arthritides (Psoriatic)
8. Reactive arthritis
What investigations would be carried out following aspiration of the joint?
Microscopy - Gram stain/ Culture + sensitivity
Histopathology
Distinguish infection from crystals
What blood tests would be carried out?
CRP
LFTs
U+E
ESR
Serum urate
Cultures
FBC
Can you name 3 other investigations that would be carried out?
X-Ray
Urine dipstick
Swabs
What are the 3 components of synovial fluid analysis?
Cells (above 50000/mm3 + above 90% neutrophils)
Chemistry (Low glucose in infection)
Macroscopic (Turbid/ Poor mucin clot/ Not viscous- inflammation)
Name 4 other risk factors for monoarthritis
FMH
1. Gout
2. Haemophillia/ other bleeding disorder
Social Hx
3. Alcoholism
4. Drug abuse
What drugs can cause sepsis?
Cytotoxic drugs
IV drug use/ abuse
Corticosteroids
What drugs can increase the risk of haemarthrosis?
Anticoagulants
What drugs increase the risk of gout?
Diuretics
Nephrotoxic drugs