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36 Cards in this Set

  • Front
  • Back
Who found the transforming principle?

Fredrich Griffith



Who said that that transforming principle is DNA?
Avery, Macleod, McCarty
Who used bacteriophages to do experiments?
Hershey and Chase
Who extracted a weak acidic substance from pus cells and used bandages?

Fiedrich Miescher

Who isolated 2 types of nucleic acid?
Pheobus Levene
Who said that the composition of adenine is equal to thymine and cytosine to guanine?
Erwin Chargaff
Who used x ray diffraction to analysis DNA?
Rosalind Franklin and Maurice Wilkins
Who made the first 3D model of DNA?
Watson and Crick
Who said there is a relationship between genes and proteins?
Archibald Garrod
Who had the 1 gene/1 polypeptide hypothesis?
Beadle and Tatum
Who said that proteins are made of amino acids covalently linked?

Sanger



Who said there are special types of RNA?
Jacobs and Monad
Who said that the genetic code reads in triplets?
Crick and Brenner
What are the 3 theories of DNA Replication?

1. Conservaation


2. Semi- conservation


3. Dispersive

Label it
Label it

1. Helicase


2. DNA polymerase


3. RNA primers


4. Okazaki Fragments


5.DNA liagase

What enzyme removes mistakes in a newly synthesized stand?
exonuclease
Whats the central Dogma?

What are the Types of RNA?

mRNA


tRNA


rRNA

What is transcription?

Transcribing the DNA into a mRNA stand



What are the modifications added to the pre-mRNA strand?



1. 5' cap


2. Poly A tail


3. Introns are cut out

What is translation?
Translating the nucleic acid code of mRNA into an amino acid sequence
What is this?
What is this?
tRNA
Whats the group of enzymes used to attach an amino acid to the tRNA?
Aminoacyl- tRNA sytnthetase
What are the binding sites for tRNA?

1. Acceptor site


2. Peptide site


3. Ejector site

What is this?
What is this?
The genetic code
What are the types of mutations?

1. silent mutation


2.missense mutation


3.nonsense mutation


4.frameshift mutation

what is this an example of?
what is this an example of?
Mutation
what are the genes that constantly need to be made?
constrictive genes

operon
What is recombinant DNA?
Dna that has been prepared in a lab by combining fragments od DNA from more than one source
what the enzyme used to cut DNA in order to make recombinant DNA?
Restriction Endonuclease
Explain what this is?
Explain what this is?

How do you make recombinant DNA?

Explain this Image
Explain this Image

What is Dideoxy Sequencing?

a method for determining the sequence of DNA fragment using dideoxynucleotides



What is this machine?
What is this machine?
Polymerase chain reaction