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7 Cards in this Set
- Front
- Back
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cyclin B
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tracks m phase
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cdc 25
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removes inhibitory phosphate
activates M-Cdk complex. |
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APC/Cdc 20 +E1 + E2
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degrades M-cycin in proteasome
mitosis stops |
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CAK and Wee 1
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primes mitosis Cdk for activation. Provides inhibitory phophate
inactivates M-Cdk cmplx. blocks mitosis |
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Mad 2
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signals are unattached kinetochores inhibit active APC
prevents degradation by ubiquitilation of securin/ seperase cmplx. |
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securin/seperase complex
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degration of s.s. complex activates seperase enzyme which cleaves cohesions
allows sister chromatids to seperate |
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what does active cdc2 phosphorylate
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1. nuclear lamins
2. histone 1 3. MAPs |
