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52 Cards in this Set

  • Front
  • Back
ADL's (5)
1)bathing
2)dressing
3)eating
4)toileting
5)ambulation
Instrumental ADL (6)
1)chores
2)money management
3)shopping
4)cooking
5)phone calls
6)medications
Old changes in Distribution for drugs (3)
1)decr Vd so incr [] of water soluble drugs
2)incr Vd and incr half-life for fat soluble drugs
3)incr/decr of highly plasma protein bound drugs
Old changes in Metabolism for drugs (4)
1)decr CL and incr half-life for oxidatively metabolized drugs
2)decr CL and incr half-life of drugs w/ high hepatic extraction
3)decr in phaseI metabolism
4)phase II metabolism is same as young person's
% using a Rx drug per week
% using a OTC per week
50%
30%
1 in ___ will use an herbal
1 in 6
WHO def of SELF CARE
Activities ppl undertake w/ intent to enhance health and prevent/get rid of disease

NOT a filaure to pursue professional medical services
Components of self-care (5)
1)NonRx meds
2)complementary therapies
3)nondrug measures
4)diagnostic tests
5)medical devices
Top 4 OTC sellers (categories)
1)cough and cold
2)analgesics
3)antacids
4)laxatives
____% of men/women have used an OTC over the last 6months (women more than men, but just one % # for your own sake ross)
75%
____% of men/women recognize the pharmacist as a good source of info about minor health problems (just one % w/ the women being more than men but just one # for you own sake ross)
50%
Highest used OTC's in old (4)
1)ASA
2)APAP
3)vitamins
4)Mg/Al antacids
More stuff to OTC b/c... (2)
1)revitalize dead products
2)time Rx to OTC w/ expiration of patent
Elderly account for what % of OTC market
33%
Pharmacists can play role in OTC selection b/c...(3)
1)education
2)access to public
3)strategic location @ source of products
3 parts to Self-Care
1)self diagnosis
2)self medication
3)self monitor
When self-care therapy is available and warranted you should? (6)
1)assist in product selection
2)assess pt factors
3)assess potential of therapy to mask more serious condition
4)counsel about proper use
5)maintain info about use
6)prevent delays in seeking appropriate medical attn
Federal Food, Drug and Cosmetic Act of 1938 put OTC drugs in 3 categories
1)RASE
2)GRASE
3)NRASE
RASE
recognized as safe
GRASE (3)
1)generally recognized as safe
2)products b4 1938 exempted from NDA's
3)is GRASE when a drug has been used by many pts for many years
NRASE (3)
1)Not recognized as safe and effective
2)drug was this until pre-cleared and approved by FDA
3)requires NDA
____ were created in response to thalidomide
DESI's- Drug Efficacy Study Implementation
What did DESI's do? (2)
1)OTC drug review process
2)All OTC's reviewed for safety and efficacy
Changes to OTC drug label (2)
1)standardized content and format for labeling
2)use lay language
Adverse consequences of inappropriate OTC use
a)direct effect
b)indirect
a)ADR, interaxns
b)delay seeing Dr.
Increasing dependence on complementary therapies (like acupuncture, herbals, homeopathy)
50% incr to complementary practitioners in US
DSHEA def of herbal supplements (3)
1)supplement diet and contain vitamin, mineral, AA, herb, botanical
2)supplement diet by incr total dietary intake
3)concentrate, metabolite, constituent, extract
DSHEA herbal labeling requirements (5)
1)states its a supplement
2)provide name and address of manufacturer
3)list all ingredients
4)must state part of plant used
5)claims are accurate and truthful but not FDA approved
3 levels of claims by DSHEA
1)Good source
2)health claims
3)structure/function claim
Health claims? (1 and ex)
1)describe relationship b/w disease and supplement

fiber maintains bowel regularity
Structure rxn claims (2 and ex)
1)expressed or implied disease claims
2)says "product not intended to diagnose, treat, etc..."
calcium builds strong bones NOT calcium treats osteoporosis
Supplements certification programs (3)
1)US Pharmacopeia Dietary Verification Program******
2)Consumerlab.com's Seal of Approval
3)NSF Int'l
Patient Care questioning format
SCHOLAR
S- symptoms
C- characteristics
H- history
O- onset
L- location
A- aggrevating factors
R- remitting factors
St. John's Wort
a)use
b)benefit/risk
a)mild/moderate depression
b)general improvement of symptoms (but JAMA says no)
Feverfew
a)use
b)benefit/risk
a)migraine
b)reduces severity and frequency
Niacin
a)use (2)
b)benefit/risk (5)
a)nutritional support, lipid lowering
b)stomach pain, vomiting, bloading, nausea, muscle/liver disease
Regurgitation
stomach contents into the pharynx and stops short of expulsion
Retching
unsuccessulf effort to vomit
Motion sickness is most common where? (2)
1)from age 2-12
2)in women
NVP? (3)
a)n/v of pregnancy
b)morning sickness
c)can result in Hyperemesis gravidarum
Most common n/v cause
viral gastroenteritis
Viral gastroenteritis (2)
a)1-2 episodes per year in kids under 5
b)300 deaths per year
Postop n/v stats (4)
1)higher w/ ENT, eye, abs
2)higher in women
3)higher in kids
4)motion sickness, obesity, incr age incr risk
Top 3 causes of n/v
1)primary causes gastric obstruction, motility disorders, intra-abdominal emergencies
NTs of major importance in vomiting (5)
1)dopamine
2)histamine
3)muscarinic
4)adrenergic 2
5)serotonin
Vomiting process...
CNS and GI coordinate by vomiting coordinating circuitry in the medulla oblongata called the VOMITING CENTER
Accompying autonomic symptoms of vomiting (3)
1)pallor
2)tachycardia
3)diaphoresis
Simple Presentation of n/v*** (4)
1)occasional and self-limiting episodes
2)relieved by miminal use of medications
3)little pt deterioration
4)not associated w/ noxious agents
Complex Presentation of n/v*** (5)
1)not relieved by admin of a single antiemetic
2)progressive pt deterioration to fluid-electrolyte imbalance
3)caused by noxious agents or psychogenic events
4)discomfort/noncompliant to other treatments
5)acute followed by delayed emesis episodes
History of symptoms you should take if person says they are n/v (5)
1)episodic
2)situational
3)acute/chronic
4)what makes it worse/better
5)exclusions to self-treat
When does NVP occur? (2)
early in day
in first trimester
Anticipatory n/v
n/v elicited by specific stimuli