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164 Cards in this Set
- Front
- Back
Proprioception |
The ability to sense the relative position of body parts |
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Sense of body positioning is determined by what three things |
Vision, balance organs, and proprioception |
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The nervous system coordinates voluntary and involuntary actions in the body by |
Sending and receiving information |
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The nervous system is comprised of an enormous number of cells primarily of two types which are |
Neurons and glial cells |
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Neurons are the ... cells |
Signaling |
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Glial cells are the... units |
Supporting |
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The neuron is the functional unit of the nervous system and is designed to |
Transmit information between cells |
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The nervous system can be divided into two major parts |
Central nervous system. Peripheral nervous system |
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The central nervous system consists of |
Neurons associated with central processing. The brain and spinal cord |
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The peripheral nervous system consists of neurons associated with |
Sensory input and motor input |
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The peripheral nervous system functions to connect the |
Central nervous system to all other parts of the body |
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The peripheral nervous system is located |
Outside of the brain and spinal cord |
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Information is transmitted between these two systems following this basic pattern |
Stimulus, receptor, afferent pathway, control center, efferent pathway, effector, and response |
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The peripheral nervous system can be further subdivided into |
Somatic nervous system. Autonomic nervous system. And enteric nervous system |
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Somatic nervous system |
Controls voluntary movement of skeletal muscle |
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Autonomic nervous system |
Regulates involuntary functions of the organs and smooth muscle tissue |
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The autonomic nervous system is further subdivided into |
Sympathetic system and parasympathetic system |
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Enteric nervous system |
Semi-independent nervous system. Controls gastrointestinal tract |
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Why is enteric nervous system semi-independent |
Can run independently or through modulation by the autonomic nervous system |
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What are the for specialized structures of the neuron |
Cell body or Soma. Dendrites. Axon. Axon terminals |
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Cell body or Soma |
The portion of the cell that surrounds the nucleus |
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The cell body or Soma plays a major role in |
Synthesizing proteins |
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Dendrites are |
Short, branched processes that extend from the cell body |
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Dendrites function to |
Receive information |
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How do dendrites receive information |
Numerous receptors located in their membranes to bind to chemicals called neurotransmitters |
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The axon is a |
Large process that extends from the cell body at a point of origin |
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The point of origin that the axon extends from is called |
Axon hillock |
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The axon functions to |
Send information |
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The axon contains |
Microtubules and is surrounded by myelin |
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In the axon microtubules are arranged inside the axon as |
Parallel arrays of long strands |
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The microtubules inside the axon act as |
Highways for the movement of material to and from the Soma |
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Anterograde transport |
Carrying materials from the Soma |
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Retrograde transport |
Transporting materials back to the Soma |
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Myelin consist of |
Separate cells that coil and wrap their membranes around the outside of the Axon |
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Myelin is essential for |
Electrical insulation and speed up action potential propagation |
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Axon terminals |
Once an axon reaches a Target it terminates to multiple endings |
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Axon terminals are designed to |
Convert the electrical signal into the chemical signals |
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Synaptic transmission |
Converting the electrical signal into a chemical signal |
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Most neurons are amitotic |
Means they lose their ability to divide |
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What is the exception to the amitotic rule |
Olfactory neurons and hippocampal regions of the brain |
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What is the lifespan of an amitotic neuron |
Near a hundred years |
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Neurons also have exceptionally High metabolic rates which requires them |
High levels of glucose and oxygen |
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Dendrites |
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Axon hillock |
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Axon terminals |
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Axon |
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Myelin sheath |
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Schwann cell |
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Node of ranvier |
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Nucleus |
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Cell body or Soma |
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Structural classifications of neurons is based upon |
Number of processes that extend out from the cell body |
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Multipolar |
Having three or more processes that extend from the cell body |
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Multipolar comprises of more than |
99% of the neurons in humans |
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What is the major neuron type found in the central nervous system and efferent divisions of the peripheral nervous system |
Multipolar neurons |
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Bipolar neurons |
Have only two processes that extend in opposite directions from the cell body |
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What are the process is called in a bipolar neuron |
One called the dendrite the other called an axon |
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Bipolar neurons are found in the |
Retina of the eye and olfactory system |
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Unipolar neurons |
Have a single, short process that extends from the cell body and then branches into two more processes that extend into opposite directions |
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In a unipolar neuron the process that extends peripherally is known as the |
Peripheral process and is associated with sensory reception |
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In a unipolar neuron the process that extends toward the CNS is the |
Central process |
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Unipolar neurons are found primarily in |
Afferent division of the pns |
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Bipolar neuron |
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Unipolar neuron |
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Multipolar neuron |
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Neurons are classified functionally according to the |
Direction in which the signal travels in relation to the CNS |
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Sensory neurons are also known as |
Afferent neurons |
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Sensory neurons transmit |
Information from the sensory receptors in the skin or to the internal organs toward the CNS for processing |
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Almost all Sensory neurons are |
Unipolar |
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Motor neurons are also known as |
Efferent neurons |
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Motor neurons transmit |
Info away from the CNS toward some type of effector |
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Motor neurons are typically |
Multipolar |
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Inter neurons are located |
Between motor and sensory pathways |
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Interneurons are highly involved in |
Signal integration |
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The vast majority of interneurons are confined Within |
The CNS |
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Can glial cells be replaced if they are damaged |
Yes |
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Glial cells compose half of the volume of the |
Brain and are more numerous than neurons |
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What are the major types of glial cells in the CNS |
Astrocyte, oligodendrocytes, ependymal cells, and microglial cell |
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Astrocytes have an enormous amount of processes that |
Wrap around blood vessels and neurons |
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Astrocytes are ideally positioned to |
Control and modify the extracellular environment around the neurons |
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Most functions of the astrocyte are attributed to |
Controlling this environment |
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Blood vessel |
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Epithelium |
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Astrocyte |
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Soma or cell body |
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Oligodendrocytes primary function |
To provide and maintain the myelin sheaths around axons |
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Myelin is the |
Insulating component of the nervous system |
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Myelin allows for |
Electrical signals to be propagated down one axon without being spread to other axons |
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Node of ranvier |
Between a trapping there is a small area of exposed Axon |
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Myelin is |
Wrapping that creates many layers of Highly compressed membranes |
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Saltatory conduction |
Myelination speeds up the conduction of action potentials down the axon by allowing Action potentials to occur only at the nodes |
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Myelination also in this is the clustering of |
Voltage gated na channels at the nodes |
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Alicia dendrocytes also play a key role in |
PH regulation of the CNS |
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What is the most common to myelinating disease of the CNS |
Multiple sclerosis |
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What is multiple sclerosis |
An Autumn immune disease that results in the selective destruction of oligodendrocytes resulting in reduction of Milan |
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Axon |
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Microtubule |
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Microfilament |
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Myelin sheath |
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Node of ranvier |
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Nucleus |
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Oligodendrocytes |
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Ependymal cell are located |
Line the cavities of the CNS |
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Ependymal cells are responsible for |
The production of cerebrospinal fluid |
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Ependymal cells are important barriers between the |
Cerebral spinal fluid and brain extracellular space |
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Ependymal cells beat there |
Cilia to help circulate the cerebrospinal fluid |
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Microglial cells are rapidly activated in the CNA in response to |
Injury |
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Injury causes microglial cells to |
Proliferate, change shape, and become phagocytic |
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Microglial cells are very important in presenting |
Antigens to lymphocytes in response to infection |
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Microglial cells activity is what two neurons |
Toxic to neurons and can result in long-term damage |
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Microglial cell |
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Neuron |
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Astrocyte |
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Oligodendrocytes |
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Ependymal cell |
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What is the myelin eating cell of the pns |
The Schwann cell |
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What is the difference between oligodendrocytes and a Schwann cell |
Oligodendrocytes are in the CNS and use multiple processes to myelinate multiple segments of an axon. A Schwann cell provides myelin for a single segment of an axon in a pns |
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Satellite cells help regulate |
The external chemical environment around neurons in the pns |
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Satellite cells are very similar to the |
Astrocyte of the CNS |
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What is different about a satellite cell than an astrocyte |
A satellite cell are highly sensitive to injury and inflammation |
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What are the specialized cells in the central nervous system |
Ependymal cells. Oligodendrocytes. Astrocytes. Microglia |
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What are the specialized cells in the peripheral nervous system |
Satellite cells and Schwann cells |
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The peripheral nervous system is divided into |
Sensory and motor divisions |
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The autonomic nervous system is divided into |
Sympathetic and parasympathetic divisions |
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The part of the neuron that conducts impulses away from the cell body is called |
An axon |
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Which cells support and protect the neurons |
Glial cells |
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Neurons are classified by |
Function and structure |
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Which nerve tissue cells control most of what enters and exits central nervous system neurons |
Astrocytes |
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Which cell type is responsible for the formation of myelin within the spinal cord |
Oligo dendrocytes |
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Which cell act as phagocytes within the central nervous system |
Microglial cells |
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This cell participates in forming the blood-brain barrier |
Astrocyte |
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Which glial cell type is most likely to be activated in response to injury |
Microglia |
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Which nerve will conduct an action potential the fastest |
Myelinated. Large-diameter nerve |
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Myelin is a |
Lipid-based material that may be produced in the pns OR CNS |
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How do neurons communicate with other neurons or cells |
Neurons propagate signals down their axons in the form of action potentials |
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Synaptic transmission |
The communication that occurs between these cells |
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What are the two types of synapses that are found in neurons |
Chemical and electrical |
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Chemical synapses |
Occur when neural membranes are very close together but remain distant leaving a space |
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Presynaptic terminal |
Part of the synapse that releases the neurotransmitter into the synapse |
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When an action potential arrives at the presynaptic terminal |
Voltage-gated calcium channels open which allows for the influx of calcium |
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The newly activated molecules in the presynaptic terminal then induce |
Exocytosis of the vesicles. Which results in the release of the neurotransmitter |
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The neurotransmitter then binds to receptors located in the postsynaptic membrane and |
Induces a conformational change. Which causes the receptor to act as a pore in the membrane for ions to move through |
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Postsynaptic terminal |
The part of the synapse that received that neurotransmitter |
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Synaptic cleft |
The narrow space between the two religions |
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Electrical synapses |
Occur when membranes are linked together via specialized protein that allows the flow of ions quickly from one cell to another |
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Where are electrical synapses found |
In heart muscle |
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Esps |
If the neurotransmitter causes the membrane potential to go towards threshold |
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What does esps stand for |
Excitatory postsynaptic potential |
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Ipsp |
An inhibitory response take the membrane potential way from threshold |
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What does ipsp stand for |
Inhibitory postsynaptic potential |
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Epsp |
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Ipsp |
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Epsp |
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The net effect of all epsp and ipsp is experienced at the |
Axon hillock |
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The ultimate goal of an epsp is to cause |
Enough change in the membrane to initiate an action potential |
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The goal of the ipsp is to cause |
A change in the membrane to prevent an action potential |
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Spatial summation |
Many a PSPs from multiple synapses can combine at the Soma which results in a much larger voltage change that can exceed threshold and cause an action potential |
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Temporal summation |
Epsps from the same synapse can also combine if they arrive in Rapid succession |
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Most excitatory synapses in the brain use |
Glutamate or aspartate as the neurotransmitter |
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Long-term potentiation |
A very important subset of synapses in the brain includes a group capable of forming Memories by increasing the activity and strength of the synapse |
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Why is nmda receptor unique |
It is both ligands and voltage regulated |
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What are the main inhibitory neurotransmitters |
Gaba and glycine |
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Modulatory synapse |
Those that can be primed by neuromodulators so they are able to respond more powerfully to other inputs |
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What is an example of a neuromodulator |
Norepinephrine |