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164 Cards in this Set

  • Front
  • Back

Proprioception

The ability to sense the relative position of body parts

Sense of body positioning is determined by what three things

Vision, balance organs, and proprioception

The nervous system coordinates voluntary and involuntary actions in the body by

Sending and receiving information

The nervous system is comprised of an enormous number of cells primarily of two types which are

Neurons and glial cells

Neurons are the ... cells

Signaling

Glial cells are the... units

Supporting

The neuron is the functional unit of the nervous system and is designed to

Transmit information between cells

The nervous system can be divided into two major parts

Central nervous system. Peripheral nervous system

The central nervous system consists of

Neurons associated with central processing. The brain and spinal cord

The peripheral nervous system consists of neurons associated with

Sensory input and motor input

The peripheral nervous system functions to connect the

Central nervous system to all other parts of the body

The peripheral nervous system is located

Outside of the brain and spinal cord

Information is transmitted between these two systems following this basic pattern

Stimulus, receptor, afferent pathway, control center, efferent pathway, effector, and response

The peripheral nervous system can be further subdivided into

Somatic nervous system. Autonomic nervous system. And enteric nervous system

Somatic nervous system

Controls voluntary movement of skeletal muscle

Autonomic nervous system

Regulates involuntary functions of the organs and smooth muscle tissue

The autonomic nervous system is further subdivided into

Sympathetic system and parasympathetic system

Enteric nervous system

Semi-independent nervous system. Controls gastrointestinal tract

Why is enteric nervous system semi-independent

Can run independently or through modulation by the autonomic nervous system

What are the for specialized structures of the neuron

Cell body or Soma. Dendrites. Axon. Axon terminals

Cell body or Soma

The portion of the cell that surrounds the nucleus

The cell body or Soma plays a major role in

Synthesizing proteins

Dendrites are

Short, branched processes that extend from the cell body

Dendrites function to

Receive information

How do dendrites receive information

Numerous receptors located in their membranes to bind to chemicals called neurotransmitters

The axon is a

Large process that extends from the cell body at a point of origin

The point of origin that the axon extends from is called

Axon hillock

The axon functions to

Send information

The axon contains

Microtubules and is surrounded by myelin

In the axon microtubules are arranged inside the axon as

Parallel arrays of long strands

The microtubules inside the axon act as

Highways for the movement of material to and from the Soma

Anterograde transport

Carrying materials from the Soma

Retrograde transport

Transporting materials back to the Soma

Myelin consist of

Separate cells that coil and wrap their membranes around the outside of the Axon

Myelin is essential for

Electrical insulation and speed up action potential propagation

Axon terminals

Once an axon reaches a Target it terminates to multiple endings

Axon terminals are designed to

Convert the electrical signal into the chemical signals

Synaptic transmission

Converting the electrical signal into a chemical signal

Most neurons are amitotic

Means they lose their ability to divide

What is the exception to the amitotic rule

Olfactory neurons and hippocampal regions of the brain

What is the lifespan of an amitotic neuron

Near a hundred years

Neurons also have exceptionally High metabolic rates which requires them

High levels of glucose and oxygen

Dendrites

Axon hillock

Axon terminals

Axon

Myelin sheath

Schwann cell

Node of ranvier

Nucleus

Cell body or Soma

Structural classifications of neurons is based upon

Number of processes that extend out from the cell body

Multipolar

Having three or more processes that extend from the cell body

Multipolar comprises of more than

99% of the neurons in humans

What is the major neuron type found in the central nervous system and efferent divisions of the peripheral nervous system

Multipolar neurons

Bipolar neurons

Have only two processes that extend in opposite directions from the cell body

What are the process is called in a bipolar neuron

One called the dendrite the other called an axon

Bipolar neurons are found in the

Retina of the eye and olfactory system

Unipolar neurons

Have a single, short process that extends from the cell body and then branches into two more processes that extend into opposite directions

In a unipolar neuron the process that extends peripherally is known as the

Peripheral process and is associated with sensory reception

In a unipolar neuron the process that extends toward the CNS is the

Central process

Unipolar neurons are found primarily in

Afferent division of the pns

Bipolar neuron

Unipolar neuron

Multipolar neuron

Neurons are classified functionally according to the

Direction in which the signal travels in relation to the CNS

Sensory neurons are also known as

Afferent neurons

Sensory neurons transmit

Information from the sensory receptors in the skin or to the internal organs toward the CNS for processing

Almost all Sensory neurons are

Unipolar

Motor neurons are also known as

Efferent neurons

Motor neurons transmit

Info away from the CNS toward some type of effector

Motor neurons are typically

Multipolar

Inter neurons are located

Between motor and sensory pathways

Interneurons are highly involved in

Signal integration

The vast majority of interneurons are confined Within

The CNS

Can glial cells be replaced if they are damaged

Yes

Glial cells compose half of the volume of the

Brain and are more numerous than neurons

What are the major types of glial cells in the CNS

Astrocyte, oligodendrocytes, ependymal cells, and microglial cell

Astrocytes have an enormous amount of processes that

Wrap around blood vessels and neurons

Astrocytes are ideally positioned to

Control and modify the extracellular environment around the neurons

Most functions of the astrocyte are attributed to

Controlling this environment

Blood vessel

Epithelium

Astrocyte

Soma or cell body

Oligodendrocytes primary function

To provide and maintain the myelin sheaths around axons

Myelin is the

Insulating component of the nervous system

Myelin allows for

Electrical signals to be propagated down one axon without being spread to other axons

Node of ranvier

Between a trapping there is a small area of exposed Axon

Myelin is

Wrapping that creates many layers of Highly compressed membranes

Saltatory conduction

Myelination speeds up the conduction of action potentials down the axon by allowing Action potentials to occur only at the nodes

Myelination also in this is the clustering of

Voltage gated na channels at the nodes

Alicia dendrocytes also play a key role in

PH regulation of the CNS

What is the most common to myelinating disease of the CNS

Multiple sclerosis

What is multiple sclerosis

An Autumn immune disease that results in the selective destruction of oligodendrocytes resulting in reduction of Milan

Axon

Microtubule

Microfilament

Myelin sheath

Node of ranvier

Nucleus

Oligodendrocytes

Ependymal cell are located

Line the cavities of the CNS

Ependymal cells are responsible for

The production of cerebrospinal fluid

Ependymal cells are important barriers between the

Cerebral spinal fluid and brain extracellular space

Ependymal cells beat there

Cilia to help circulate the cerebrospinal fluid

Microglial cells are rapidly activated in the CNA in response to

Injury

Injury causes microglial cells to

Proliferate, change shape, and become phagocytic

Microglial cells are very important in presenting

Antigens to lymphocytes in response to infection

Microglial cells activity is what two neurons

Toxic to neurons and can result in long-term damage

Microglial cell

Neuron

Astrocyte

Oligodendrocytes

Ependymal cell

What is the myelin eating cell of the pns

The Schwann cell

What is the difference between oligodendrocytes and a Schwann cell

Oligodendrocytes are in the CNS and use multiple processes to myelinate multiple segments of an axon. A Schwann cell provides myelin for a single segment of an axon in a pns

Satellite cells help regulate

The external chemical environment around neurons in the pns

Satellite cells are very similar to the

Astrocyte of the CNS

What is different about a satellite cell than an astrocyte

A satellite cell are highly sensitive to injury and inflammation

What are the specialized cells in the central nervous system

Ependymal cells. Oligodendrocytes. Astrocytes. Microglia

What are the specialized cells in the peripheral nervous system

Satellite cells and Schwann cells

The peripheral nervous system is divided into

Sensory and motor divisions

The autonomic nervous system is divided into

Sympathetic and parasympathetic divisions

The part of the neuron that conducts impulses away from the cell body is called

An axon

Which cells support and protect the neurons

Glial cells

Neurons are classified by

Function and structure

Which nerve tissue cells control most of what enters and exits central nervous system neurons

Astrocytes

Which cell type is responsible for the formation of myelin within the spinal cord

Oligo dendrocytes

Which cell act as phagocytes within the central nervous system

Microglial cells

This cell participates in forming the blood-brain barrier

Astrocyte

Which glial cell type is most likely to be activated in response to injury

Microglia

Which nerve will conduct an action potential the fastest

Myelinated. Large-diameter nerve

Myelin is a

Lipid-based material that may be produced in the pns OR CNS

How do neurons communicate with other neurons or cells

Neurons propagate signals down their axons in the form of action potentials

Synaptic transmission

The communication that occurs between these cells

What are the two types of synapses that are found in neurons

Chemical and electrical

Chemical synapses

Occur when neural membranes are very close together but remain distant leaving a space

Presynaptic terminal

Part of the synapse that releases the neurotransmitter into the synapse

When an action potential arrives at the presynaptic terminal

Voltage-gated calcium channels open which allows for the influx of calcium

The newly activated molecules in the presynaptic terminal then induce

Exocytosis of the vesicles. Which results in the release of the neurotransmitter

The neurotransmitter then binds to receptors located in the postsynaptic membrane and

Induces a conformational change. Which causes the receptor to act as a pore in the membrane for ions to move through

Postsynaptic terminal

The part of the synapse that received that neurotransmitter

Synaptic cleft

The narrow space between the two religions

Electrical synapses

Occur when membranes are linked together via specialized protein that allows the flow of ions quickly from one cell to another

Where are electrical synapses found

In heart muscle

Esps

If the neurotransmitter causes the membrane potential to go towards threshold

What does esps stand for

Excitatory postsynaptic potential

Ipsp

An inhibitory response take the membrane potential way from threshold

What does ipsp stand for

Inhibitory postsynaptic potential

Epsp

Ipsp

Epsp

The net effect of all epsp and ipsp is experienced at the

Axon hillock

The ultimate goal of an epsp is to cause

Enough change in the membrane to initiate an action potential

The goal of the ipsp is to cause

A change in the membrane to prevent an action potential

Spatial summation

Many a PSPs from multiple synapses can combine at the Soma which results in a much larger voltage change that can exceed threshold and cause an action potential

Temporal summation

Epsps from the same synapse can also combine if they arrive in Rapid succession

Most excitatory synapses in the brain use

Glutamate or aspartate as the neurotransmitter

Long-term potentiation

A very important subset of synapses in the brain includes a group capable of forming Memories by increasing the activity and strength of the synapse

Why is nmda receptor unique

It is both ligands and voltage regulated

What are the main inhibitory neurotransmitters

Gaba and glycine

Modulatory synapse

Those that can be primed by neuromodulators so they are able to respond more powerfully to other inputs

What is an example of a neuromodulator

Norepinephrine