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18 Cards in this Set
- Front
- Back
Module 4 - logbook 10: definition trifasicular block |
Bifasicular block: RBBB+ L anterior/L posterior block Incomplete: bifasicular block + 1st*/2nd degree AV block or RBBB and alternating LA/LP block (both) Complete: 3rd degree AV block |
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Module 4 - logbook 10: aetiology |
IHD, hypertension, aortic stenosis, anterior MI, congenital heart disease and hyperkalaemia |
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Module 4 - logbook 10: epidemiology |
X |
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Module 4 - logbook 10: risk factors |
Age (fibrosis) and heart disease |
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Module 4 - logbook 10: common presentation |
Often asymptomatic. Syncope, fatigue, hypotension and dyspnoea. HR needs to be < 50bpm to affect CO
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Module 4 - logbook 10: investigations |
ECG, 12 lead ECG,echocardiogram and possibly electrophysiology (catheter which measures electrical activity of heart - detects whether PR interval is coming from AV or lower down) |
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Module 4 - logbook 10: pathophysiology |
AV node: fibrosis or ischaemia (AV node is often supplied by RCA) Below AV node: Ischaemia/infarction and disrupts ventricular depolarisation producing wider QRS complexes. LBBB - septum depolarises L > R but reversed RBBB (normal septal depolarisation R > L but LV depolarises before RV) |
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Module 4 - logbook 10: prognosis |
Can develop to complete heart block but not often |
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Module 4 - logbook 10: management |
Medication, cardiovascular risk and pacemaker: 3 types 1. standard (different chamber combinations) sense (what's going on) and capture (depolarize) 2. ICD defibrillator 3. CRT co-ordination |
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Module 4 - logbook 10: drugs - CANDESARTAN |
ARB - stops AT II from binding to smooth muscle |
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Module 4 - logbook 10: drugs - BISOPROLOL |
Beta blocker inhibits sympathetic stimulus on beta 1 adrenergic receptors |
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Module 4 - logbook 10: drugs - WARFARIN |
Vitamin K antagonist, precursor of clotting facotrs |
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Module 4 - logbook 10: drugs - ASPIRIN |
Antiplatelet - COX inhibitor reducing the amount of thromboxane A2 |
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Module 4 - logbook 10: drugs - PARACETAMOL |
Non opioid analgesic - COX 1,2 (and 3?) inhibitor - reducing prostaglandin synthesis |
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Module 4 - logbook 10: drugs - FUROSEMIDE |
Loop diuretic - acting on loop of Henle, blocks sodium potassium chloride co-trnasporter. Less sodium, reduces osmotic gradient >> less water retention |
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Module 4 - logbook 10: drugs - SIMVASTATIN |
Statin - enzyme inhibitor. competes HMG coA for HMG co-A reductase. Works on mevalonic pathway, reduces mevalonic acid which is precursor of cholesterol |
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Module 4 - logbook 10: drugs - AMIODERONE |
Anti - arrhythmic (class III). Prolongs phase 3 of cardiac action potential where there is decreased calcium and increased potassium. Also acts on sodium and potassium channels in the SA and AV nodes |
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Module 4 - logbook 10: anti-arrhythmic drugs (general) |
Class 1 - sodium channel blockers (3 classes) 1. delays and prolongs, 2. delays a bit + shortens, 3. delays a lot but plateau the same Class 2 - Beta blockers Class 3 - potassium channel blockers Class 4 - calcium
Calcium is slow - AV and SA Sodium is fast - ventricles
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