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18 Cards in this Set

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Module 4 - logbook 10: definition trifasicular block

Bifasicular block: RBBB+ L anterior/L posterior block


Incomplete: bifasicular block + 1st*/2nd degree AV block or RBBB and alternating LA/LP block (both)


Complete: 3rd degree AV block

Module 4 - logbook 10: aetiology

IHD, hypertension, aortic stenosis, anterior MI, congenital heart disease and hyperkalaemia

Module 4 - logbook 10: epidemiology

X

Module 4 - logbook 10: risk factors

Age (fibrosis) and heart disease

Module 4 - logbook 10: common presentation

Often asymptomatic. Syncope, fatigue, hypotension and dyspnoea. HR needs to be < 50bpm to affect CO


Module 4 - logbook 10: investigations

ECG, 12 lead ECG,echocardiogram and possibly electrophysiology (catheter which measures electrical activity of heart - detects whether PR interval is coming from AV or lower down)

Module 4 - logbook 10: pathophysiology

AV node: fibrosis or ischaemia (AV node is often supplied by RCA)


Below AV node: Ischaemia/infarction and disrupts ventricular depolarisation producing wider QRS complexes.


LBBB - septum depolarises L > R but reversed


RBBB (normal septal depolarisation R > L but LV depolarises before RV)

Module 4 - logbook 10: prognosis

Can develop to complete heart block but not often

Module 4 - logbook 10: management

Medication, cardiovascular risk and pacemaker:


3 types


1. standard (different chamber combinations) sense (what's going on) and capture (depolarize)


2. ICD defibrillator


3. CRT co-ordination

Module 4 - logbook 10: drugs - CANDESARTAN

ARB - stops AT II from binding to smooth muscle

Module 4 - logbook 10: drugs - BISOPROLOL

Beta blocker inhibits sympathetic stimulus on beta 1 adrenergic receptors

Module 4 - logbook 10: drugs - WARFARIN

Vitamin K antagonist, precursor of clotting facotrs

Module 4 - logbook 10: drugs - ASPIRIN

Antiplatelet - COX inhibitor reducing the amount of thromboxane A2

Module 4 - logbook 10: drugs - PARACETAMOL

Non opioid analgesic - COX 1,2 (and 3?) inhibitor - reducing prostaglandin synthesis

Module 4 - logbook 10: drugs - FUROSEMIDE

Loop diuretic - acting on loop of Henle, blocks sodium potassium chloride co-trnasporter. Less sodium, reduces osmotic gradient >> less water retention

Module 4 - logbook 10: drugs - SIMVASTATIN

Statin - enzyme inhibitor. competes HMG coA for HMG co-A reductase. Works on mevalonic pathway, reduces mevalonic acid which is precursor of cholesterol

Module 4 - logbook 10: drugs - AMIODERONE

Anti - arrhythmic (class III). Prolongs phase 3 of cardiac action potential where there is decreased calcium and increased potassium. Also acts on sodium and potassium channels in the SA and AV nodes

Module 4 - logbook 10: anti-arrhythmic drugs (general)

Class 1 - sodium channel blockers (3 classes) 1. delays and prolongs, 2. delays a bit + shortens, 3. delays a lot but plateau the same


Class 2 - Beta blockers


Class 3 - potassium channel blockers


Class 4 - calcium



Calcium is slow - AV and SA


Sodium is fast - ventricles