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10 Cards in this Set
- Front
- Back
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Bromociptine |
Dopamine agonist; treatment of prolactin-secreting tumors |
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Octreotide |
Somatostatin analogue; treatment of diarrhea associated with islet cell neoplasms |
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Mitotane |
Adrenal steroid synthesis inhibitor; useful for adrenocortical carcinoma |
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Aminoglutethimide Ketoconazole |
Adrenal sex steroid hormone synthesis inhibitor; used as adjuncts in the management of sex hormone-dependent malignancies |
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Flutamide Bicalutamide |
Androgen receptor blockers |
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Leuprolide Goserelin |
LHRH agonists; they induce tonic stimulation of the LHRH receptor with the loss of its normal pulsatile activation --> decreased output of LH by the anterior pituitary |
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Anastrozole Letrozole |
Reversible aromatase inhibitor; superior to tamoxifen in the adjuvant treatment of breast CA in postmenopausal patient with estrogen receptor (+) tumors |
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Exemestane |
Irreversible aromatase inhibitor |
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Osteoporosis |
Major adverse effect of aromatase inhibitor |
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Tamoxifen |
Partial estrogen receptor agonist (mixed agonist-antagonist); greater activity in breast CA tissue estrogen receptor (+) |
