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79 Cards in this Set
- Front
- Back
Where does the pulmonary vein go from-to?
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right ventricle to lungs
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Where does the bronchial vein go from-to?
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lungs to right atrium
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Where does the bronchopulmonary vein go from-to?
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lungs to pulmonary vein
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Where does the pulmonary artery go from-to?
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heart to lungs
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Where does the bronchial artery go from-to?
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left ventricle to lungs
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What causes a low V/Q mismatch? What causes a high V/Q mismatch?
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shunt <1, alveolar dead space >1
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What do alpha receptors do to vessels? What do beta receptors do to vessels?
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a = vc, b = vd
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What is wasted volume in alveolar ventilation?
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dead space in the conducting zone
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What is anatomic dead space? Where is it located?
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breath that doesn't participate in gas exchange; conducting zone
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What is alveolar dead space?
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no blood comes to alveoli
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What is minute ventilation? What is the usual number?
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total air moved in and out of lung; 10 mL/kg
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What is alveolar ventilation?
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the volume of air available for gas exchange
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What are the 5 things that can change the diffusion of gases across the respiratory membrane?
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thickness, SA, diffusion coeff, a:v pressure gradient, pulmonary capillary transit time
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How much more soluble is CO2 than O2?
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20x
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What 2 general things can cause alveolar dead space?
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pulmonary thrombosis, low CO
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How does the body compensate for alveolar dead space?
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local broncoconstriction to affected alveoli
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What happens in shunt?
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blood reaches the alveoli but there is no air available for gas exchange
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How does the body compensate for shunt?
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hypoxic pulmonary vasoconstriction
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Why is the PaO2 of systemic arterial blood less than PaO2 of pulmonary venous blood?
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bronchopulmonary vein and thesbian vessels
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How much oxygen is bound to Hb? How is this measured?
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97%, pulse ox
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How much oxygen is dissolved to Hb? How is this measured?
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3%, measured by PO2
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What is saturation binding of Hb with oxygen dependent in?
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partial pressure of dissooved oxygen
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How is dissolved bicarb measured? How is bound to Hb bicarb measured?
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PCO2, not measured
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How does the medulla control ventilation?
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rate and depth of breath
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How do the central chemorecepotrs control ventilation?
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detect H+ in CSF
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How do peripheral chemoreceptors control vasodilation?
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sensitive change in O2, CO2 and H+ in blood
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What can override central chemoreceptor control and send signals to medulla?
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peripheral chemoreceptors
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What are the 4 types of hypoxia?
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low dissolved O2 in blood, low numbers of RBC, low blood flow to tissues, cellular metabolic dysfunction
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What is hypoventilation PaCO2?
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>45mmHg
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What is hyperventilation PaCO2?
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<35mmHg
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What is hypoventilation PaO2?
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<80mmHg
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What is eupnea?
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normal breathing
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What is stertor?
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snoring due to obstruction
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What is stridor?
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shrill sound with laryngeal obstruction
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What is a wheeze?
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obstruction in the conducting zone
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What is crackle due to?
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pulmonary edema
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At what concentration of Hb do you see cyanosis?
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>5 g/dL
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What is a common signalment of laryngeal parlysis /obstruction/ collapse?
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labs with exercise intolerance
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What is the underlying cause of laryngeal parlysis?
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dysfunction of recurrent laryngeal nerve
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What is the underlying cause of laryngeal obstruction?
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mass, saccule, foreign body
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What is the underlying cause of laryngeal collapse?
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laryngeal cartilage
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What are signs of laryngeal parlysis /obstruction/ collapse?
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inspiratory stridor and stertor, increased respiratory effort, heat intolerance
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If laryngeal parlysis /obstruction/ collapse is severe, what can it result in?
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hypoxemia, hypoventilation
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What are the 2 causes of tracheal bronchial collapse? What is one major form?
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congenital and acquired; enlarged left atrium
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What are the signs of tracheal bronchial collapse?
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goose-honk cough, expiratory wheeze, increased respiratory effort
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What can tracheal bronchial collapse result in if severe?
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hypoxemia, shunt, hypoventilation
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How can you treat tracheal collapse?
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tracheal stent
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What are the drugs given in tracheal bronchial collapse?
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cough suppressants, bronchodilators, anxiolysis
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Why is there a cough in tracheal bronchial collapse due to enlarged left atrium?
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upper airway irritant receptors
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What are 2 upper airway disorders?
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laryngeal paralysis/obstruction/collapse, tracheal bronchial collapse
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What are 4 small airway and alveolar disorders?
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chronic bronchitis, asthma, pulmonary edema, aspiration pneumonia
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Which animals get chronic bronchitis?
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dogs
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what is chronic bronchitis obstruction due to?
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hypertrophy of smooth muscles, fibrosis, mucus gland hyperplasia
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What are the signs in chronic bronchitis?
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inspiratory crackles, expiratory wheezes, cough, excitement intolerance
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What can chronic bronchitis lead to?
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hypoxemis, shunt, hypoventilation
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What disease results in increased expiratory effort with prolonged expiratory time?
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chronic bronchitis
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What are pathneumonic in xrays in chronic bronchitis?
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trail lines and doughnuts
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What is COPD? What is this called in horses?
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chronic bronchitis with emphysema; heaves
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What animals get astham?
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cats
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What is asthma?
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small airway hyper-responsive inflammatory condition
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What are 3 causes of asthma?
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Obstruction via smooth muscle constriction and hypertrophy, bronchial wall edema, mucus gland hyperplasia
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Why does asthma cause coughing?
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stimulation of irritant receptors in lower airways
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What are the signs of asthma?
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cough, wheeze, loud breathing, dyspnea, open-mouth breathing
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What can asthma cause?
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shunt
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In which disease do you see prolonged expiratory phase with increased effort and air trapping?
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asthma
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Where does fluid accumulate in pulmonary edema?
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interstitium and alveoli
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What are the 4 cauases of pulmonary edema?
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Increased vascular hydrostatic pressure, Decreased plasma oncotic pressure, Increased vascular permeability, Impaired lymph drainage
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What signs do you see with pulmonary edema?
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tachypnea, cough, increased inspiratory and expiratory effort and inspiratory crackles
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What can pulmonary edema cause?
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hypoxemia, shunt
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What does stimulation of J receptors cause?
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dyspnea, tachypnea
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Why does aspiration penumonia cause pulmonary inflammation?
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toxicity, chemical damage, drowning
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What signs does aspiration pneumonia cause?
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acute onset respiratory distress, dyspnea/tachypnea, inspiratory and expiratory cracles and wheezes and cough
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What is the #1 cause of anesthetic mortality?
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aspiration pneumonia
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What do pleural space disorders result in if severe?
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atelectasis
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What do pleural space disorders result in if chronic?
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pleuritis
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What should the difference between EtCO2 and PaCO2 be?
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<5mmHg
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What is pulmonary hypertension due to?
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increased LA pressure, increased pulmonary blood flow, or increased pulmonary vascular resistance
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What is pulmonary atery systolic pressure?
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>25mmHg
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How do you treat pulmonary hypertension?
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pulmonary vasodilators
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