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26 Cards in this Set

  • Front
  • Back
Anticogulants prevent
vascular clots from forming
thrombolytics agents disslove
already existing blood clots
antiplatelet agents
prevent adhesion & aggregation of platlets
what is Afterload


Afterload=arteries
atrioles are the resistance vessels and regulate the force against which the heart must pump
types of hypertensives
Alpha & Beta Blockade
Diuretics
Vasodilators
ACE inhibitors: angiotensin converting enzyme
Ca Channel Blockers
Urgent anti-hypertensives
what is preload


PRELOAD=VEINS
amot of blood returning to the heart and contained in the ventricles prior to contraction
CO X TPR =
CARDIAC OUTPUT X TOTAL PERIPHERAL RESISTANCE=BLOOD PRESSURE
THESE DECREASE TOTAL PERIPHERAL RESISTANCE OR VOL REDUCTION (7)
CENTRAL & PERIPHERAL SYMPATHOLYTICS
VASODILATORS
CALCIUM CHANNEL BLOCKERS
DIURETICS
ACE INHIBITORS
ANGIOTENSIN ANTAGONISTS
DECREASE CARDIAC OUTPUT (1)
BETA BLOCKERS
Anti-Adrenergics (SYMPATHOLYTICS)

CLONIDINE (CATAPRES)
GUANFACINE (TENEX)
Alpha 2 agonists (CNS) vasoconstriction blocks Nor Epi, Alpha 1 (PNS) vasodialates
sympatholytics rhyme
one fish, two fish makes it big then small blcoks nor epi with with clonidine and guafacine
Beta Blocker

Metaprolol
Atenolol
Propranolol

hint:beta blocker look at the MAP it lives DOWN in HR CO
inhibits sympathetic activity
decrease HR & CO
Diuretics
LOOP furosemide (lasix)
THIAZIDE hydrachlorothiazide (HYDRODIURIL), K+ sparing spironolactone (Aldactone)
Ace Inhibitor

hint: pril
angiotension II causes release of aldosterone which increase Na & H2O reabsorption=increase blood vol *benazepril (lotensin),captopril (capoten),enalapril (vasotec)
Ca Channel Blocker
produces arteriole relaxation

Verapamil (calan)
Diltiazem (cardizem)
Emergency Anti-hypertensives
Na nitroprusside causes peripheral vasodilation.
Thrombus
stationary clot
Embolus
moving clot, referred to as thromboembolism.
Anti-Coagulants
Prevent clog formation in at-risk patients (usually DVT)
Heparin
Parenteral anti-coag

Occurs naturally in mast cells
Goal is to increase clotting time to 2 – 3 times the normal (to 22 – 27 seconds)
PTT test is used to make dosage adjustments.

SE: bleeding, watch for petechiae, hematuria and GI bleed.

Antidote is protamine sulfate.
heparin binds with Antithrombin III to inhibit
thrombin of fibrinogen to fibrin
warfarin MOA
Blocks Vitamin K which is needed to chang thromboplastin to prothrombin
Warfarin
Oral anti-coags

Warfarin (coumadin)

Inhbit Vit K
Prevents blood clots

INR (replaced PT) to monitor

SE: bleeding gums, petechiae, nose bleeds.

hazard: anything that effects vit K such as yellow or green leafy veggies.
Asprin
antiplatelet

inhibits enzyme required for thromboplastin release.
order of clot MOA
platelet aggregation

thromboplastin

prothrombin

thrombin

fibrinogen
Altepase
Urokinase
streptokinase
Thrombolytics (fibrolytic)
Dissolve existing clots