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26 Cards in this Set
- Front
- Back
Anticogulants prevent
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vascular clots from forming
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thrombolytics agents disslove
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already existing blood clots
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antiplatelet agents
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prevent adhesion & aggregation of platlets
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what is Afterload
Afterload=arteries |
atrioles are the resistance vessels and regulate the force against which the heart must pump
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types of hypertensives
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Alpha & Beta Blockade
Diuretics Vasodilators ACE inhibitors: angiotensin converting enzyme Ca Channel Blockers Urgent anti-hypertensives |
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what is preload
PRELOAD=VEINS |
amot of blood returning to the heart and contained in the ventricles prior to contraction
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CO X TPR =
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CARDIAC OUTPUT X TOTAL PERIPHERAL RESISTANCE=BLOOD PRESSURE
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THESE DECREASE TOTAL PERIPHERAL RESISTANCE OR VOL REDUCTION (7)
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CENTRAL & PERIPHERAL SYMPATHOLYTICS
VASODILATORS CALCIUM CHANNEL BLOCKERS DIURETICS ACE INHIBITORS ANGIOTENSIN ANTAGONISTS |
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DECREASE CARDIAC OUTPUT (1)
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BETA BLOCKERS
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Anti-Adrenergics (SYMPATHOLYTICS)
CLONIDINE (CATAPRES) GUANFACINE (TENEX) |
Alpha 2 agonists (CNS) vasoconstriction blocks Nor Epi, Alpha 1 (PNS) vasodialates
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sympatholytics rhyme
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one fish, two fish makes it big then small blcoks nor epi with with clonidine and guafacine
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Beta Blocker
Metaprolol Atenolol Propranolol hint:beta blocker look at the MAP it lives DOWN in HR CO |
inhibits sympathetic activity
decrease HR & CO |
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Diuretics
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LOOP furosemide (lasix)
THIAZIDE hydrachlorothiazide (HYDRODIURIL), K+ sparing spironolactone (Aldactone) |
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Ace Inhibitor
hint: pril |
angiotension II causes release of aldosterone which increase Na & H2O reabsorption=increase blood vol *benazepril (lotensin),captopril (capoten),enalapril (vasotec)
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Ca Channel Blocker
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produces arteriole relaxation
Verapamil (calan) Diltiazem (cardizem) |
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Emergency Anti-hypertensives
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Na nitroprusside causes peripheral vasodilation.
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Thrombus
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stationary clot
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Embolus
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moving clot, referred to as thromboembolism.
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Anti-Coagulants
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Prevent clog formation in at-risk patients (usually DVT)
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Heparin
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Parenteral anti-coag
Occurs naturally in mast cells Goal is to increase clotting time to 2 – 3 times the normal (to 22 – 27 seconds) PTT test is used to make dosage adjustments. SE: bleeding, watch for petechiae, hematuria and GI bleed. Antidote is protamine sulfate. |
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heparin binds with Antithrombin III to inhibit
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thrombin of fibrinogen to fibrin
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warfarin MOA
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Blocks Vitamin K which is needed to chang thromboplastin to prothrombin
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Warfarin
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Oral anti-coags
Warfarin (coumadin) Inhbit Vit K Prevents blood clots INR (replaced PT) to monitor SE: bleeding gums, petechiae, nose bleeds. hazard: anything that effects vit K such as yellow or green leafy veggies. |
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Asprin
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antiplatelet
inhibits enzyme required for thromboplastin release. |
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order of clot MOA
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platelet aggregation
thromboplastin prothrombin thrombin fibrinogen |
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Altepase
Urokinase streptokinase |
Thrombolytics (fibrolytic)
Dissolve existing clots |