Mod Iv Pharm- Chf Drugs

Front 1

function unit of the kidney

Back 1

nephron

Front 2

what id the nephron comprised of??? parts is parts

Back 2

glomerus,proximal convoluted tubule,loop of henle,distal convoluted tubule and collecting duct

Front 3

what do the kidneys do?

Back 3

maintain fluid and electrolyte balance

electrolytes=acid base balance
sodium and water=blood vol

Front 4

how do diutretics work

Back 4

don't allow Na to be reabsorbed back into the peritubular capillary system (bloodstream)

Front 5

how do they classify diuretics?

Back 5

the site of the nephrom where they work

Front 6

Loop Diuretics MOA

Back 6

very potent stop reabsorption of Na & Cl in the proximal and distal tubules & the Loop of Henle.

SE:Can lead to hypochloremia or hypokalemia, resulting in metabolic alkalosis.

Front 7

furosemide (Lasix)

Back 7

Loop Diuretics

Front 8

Thiazide Diuretics MOA

Back 8

stop Na & Cl reabsorption in the distal tubule = increases water loss.

There is also a decrease in K

SE: metabolic alkalosis

Front 9

Chlorothiazide (Diuril), Hydrochlorothiazide (Esidrix)

Back 9

Thiazide Diuretics

Front 10

Potassium Sparing MOA

Back 10

block Na reabsorption in the distal tubule, decreasing the loss of K where it normally exchanges for Na.

Na & Cl is excreted along with water.

Front 11

Spironolactone (Aldactone)

Back 11

Potassium Sparing

Front 12

Osmotic Diuretics MOA

Back 12

filtered through glomerulus but not reabsorbed in the tubules

they carry an osmotic equivalent so water is excreted.

Front 13

Mannitol (Osmitrol) Isosorbide (Ismotic)

Back 13

Osmotic Diuretics

Front 14

Acetazolamide (Diamox)

Back 14

Carbonic Anhydrase Inhibitors