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14 Cards in this Set

  • Front
  • Back
function unit of the kidney
nephron
what id the nephron comprised of??? parts is parts
glomerus,proximal convoluted tubule,loop of henle,distal convoluted tubule and collecting duct
what do the kidneys do?
maintain fluid and electrolyte balance

electrolytes=acid base balance
sodium and water=blood vol
how do diutretics work
don't allow Na to be reabsorbed back into the peritubular capillary system (bloodstream)
how do they classify diuretics?
the site of the nephrom where they work
Loop Diuretics MOA
very potent stop reabsorption of Na & Cl in the proximal and distal tubules & the Loop of Henle.

SE:Can lead to hypochloremia or hypokalemia, resulting in metabolic alkalosis.
furosemide (Lasix)
Loop Diuretics
Thiazide Diuretics MOA
stop Na & Cl reabsorption in the distal tubule = increases water loss.

There is also a decrease in K

SE: metabolic alkalosis
Chlorothiazide (Diuril), Hydrochlorothiazide (Esidrix)
Thiazide Diuretics
Potassium Sparing MOA
block Na reabsorption in the distal tubule, decreasing the loss of K where it normally exchanges for Na.

Na & Cl is excreted along with water.
Spironolactone (Aldactone)
Potassium Sparing
Osmotic Diuretics MOA
filtered through glomerulus but not reabsorbed in the tubules

they carry an osmotic equivalent so water is excreted.
Mannitol (Osmitrol) Isosorbide (Ismotic)
Osmotic Diuretics
Acetazolamide (Diamox)
Carbonic Anhydrase Inhibitors