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21 Cards in this Set
- Front
- Back
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What are the causes of microangiopathic hemolytic anemia?
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disseminated intravascular coagulation,
thrombotic thrombocytopenic purpura, hemolytic-uremic syndrome, and artificial heart valves |
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Hemoglobin electrophoresis confirms the diagnosis of what 2 types of anemia?
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Thalassemia and sickle cell disease
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What viruses may cause aplastic anemia?
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Hepatitis and parvovirus B19
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What is the most common type of childhood leukemia?
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Acute lymphocytic leukemia. 75% of cases occur in children less than 15 years of age. The rest of the cases occur after age 50.
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What type of leukemia is most commonly seen in elderly men?
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Chronic lymphocytic leukemia
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What is the first-line chemotherapy agent for chronic lymphocytic leukemia?
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Chlorambucil
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Which ALL patient generally has a better prognosis: a child or an adult?
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98% of children achieve complete remission after 4 weeks of chemotherapy, and 70% of children will be cured. Only 30-40% of adults will be cured.
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What 2 types of leukemia may have the Philadelphia chromosome?
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Acute lymphocytic leukemia (its presence indicates a poorer prognosis)
and Chronic myelogenous leukemia (present in 95% of cases) |
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What is the most common form of adult leukemia in Western countries?
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Chronic lymphocytic leukemia
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Which type of leukemia will have smudge cells on the peripheral blood smear?
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Chronic lymphocytic leukemia
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What is the most deadly phase of chronic myelogenous leukemia?
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Acute blast crisis phase (>30% blasts in blood or bone marrow)
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What type of leukemia have lymphocytes with hairlike cytoplasmic projections?
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Hairy cell leukemia
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Hodgkin's lymphoma has a bimodal age distribution. When are they?
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The first peak is in the second and third decades of life, the second peak is after the age of 50
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What type of lymphoma may be linked with EBV?
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Hodgkins
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What does the presence of B symptoms in Hodgkins lymphoma indicate?
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Poor prognosis
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What test will confirm your diagnosis of multiple myeloma?
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Protein electrophoresis may show IgM proteins or Bence Jones proteins
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Hemophilia A is a deficiency of what coagulation factor?
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Factor VIII
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Hemophilia B is a deficiency of what coagulation factor?
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Factor IX
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What disease is an autoimmune bleeding disorder in which patients develop antibodies against their own platelets?
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Idiopathic Thrombocytopenic Purpura (ITP)
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Name some things that can cause disseminated intravascular coagulation.
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Obstetric complications (amniotic fluid embolism, retained dead fetus, abruptio placenta), transfusion reactions, malignancy, trauma (brain injury, crush injury, burns), infection or sepsis, acute pancreatitis, ARDS
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What lab test can be used to monitor effective response to treatment in patients with iron-deficiency anemia?
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Reticulocyte count
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