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73 Cards in this Set
- Front
- Back
White Matter in Spinal Cord:
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relays information spinothalmically (ascending) and corticospthamically (descending)
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Lateral horn contains cell bodies of:
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autonomic efferent fibers
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Ventral horn contains cell bodies of:
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somatic efferent neurons
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Dorsal horn contains cell bodies of:
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interneurons where afferent neurons terminate
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What do dorsal root ganglion connect and what kind of fibers do they have?
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cord and PNS; sensory
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Where is the convergence of the ventral and dorsal roots?
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spinal nerve
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What kind of fibers do ventral root ganglion have?
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motor
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Which nerves innervate the PNS?
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spinal that branch out
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Which is more dense: white or gray spinal matter?
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Gray
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What gives white matter it's color?
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Myelination
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The dorsal horn has what kind of neuronal synapses?
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sensory
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What is a ganglion?
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collection of synapses
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Pre-ganglionic cell bodies are in:
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the CNS
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Where do you find short pre-g fibers and long post-g fibers?
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SNS
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Where do you find long pre-g fibers and short post-g fibers?
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ParaNS
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Pre-g cell bodies of the SNS are found:
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between the T1 and L3 vertabrae
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Chain ganglia are also known as:
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paravertebral ganglia
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Where do pre-ganglionic fibers project from and where does it go?
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The spinal nerve and branches to the PVG
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What are the two prevertebral ganglia?
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Celiac and Hypogastric
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The ParaNS has pre-g fibers in the form of:
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cranial and sacral nerves
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Which nerves enervate the ParaNS?
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CN III, VII, IX, & X and S2-S4 spinal nerves
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What are the two major NTs of the ANS?
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ACh and NE
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What are the two types of ACh Receptors?
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muscarinic and nicotinic
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What are the two types of adrenergic receptors?
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Alpha (1,2,3) & Beta (1, 2)
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Tone is:
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how active one division of the ANS is in relation to the other
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pre-vertebral ganglia:
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lie outside of the PVG
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T/F: There can be more than 1 synapse at the pre-g in the SNS
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False
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What are the three possible 1st synapses in the SNS?
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Synapse at chain ganglia, synapse at distant chain ganglia and synapse at pre-vertebral ganglia
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Hypogastric and Celiac refer to:
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pre-vertebral ganglia of the SNS
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In the ANS, what is the chain of events?
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a first neuron (preganglionic) synapses on a second (post-ganglionic) onto a receptor cell (which can be another neuron)
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Which division of the ANS enervates the adrenal glands?
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SNS
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What does the adrenal medulla secrete?
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NE & E
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PNS cell bodies are located in either:
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the brain stem of S2-S4
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In the PNS, 1st synapses occur at:
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many, many ganglia that are very close to or directly on the target organ
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Where does the majority of ParaNS enervation originate?
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The Vagus nerve (CN X)
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Is the SNS adrenergic or cholinergic?
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Adrenergic
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In the ParaNS, where does the ACH released by the pre-g neuron bind to?
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the nACH (nicotinic ACH) receptor
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In the ParaNS, where does ACH bind to on the target organ?
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the mACH (muscarinic ACH) receptors
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Can E have both a neuronal and hormonal response?
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Yes
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What are the three possible hormone effects on a target cell?
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Membrane Effects - alters channel
permeability by acting on pre-existing channel-forming proteins or Enzyme Activation - acts through second-messenger system to alter activity of pre-existing proteins or 3. Activates specific genes to cause formation of new proteins |
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Alpha-1 receptor:
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vasoconstriction; slightly higher BA for NE; located on smooth muscle
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Alpha-2 receptor:
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control of synaptic transmission; regulate how much NE gets released by the pre-synaptic cell (which is where it occurs);
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Beta-2 receptor:
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vasodilation of lungs and smooth muscle; higher binding affinity for E
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Beta-1 receptor:
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increased HR and contractility; binding affinity equal
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What enzyme can be hormone-induced?
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phosphorylation enzyme (protein kinase)
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What are neurohormones?
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secretions of neurons that are released into bloodstream and act at a distant site
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Amino acid chains form what kind of hormone?
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Peptide
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Which hormone type is hydrophilic?
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Peptide
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What is the only site of action for peptide hormones?
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membrane receptors
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Which hormone type has faster cellular response?
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Peptide
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Amine hormones are a subtype of what type?
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Peptide
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What kind of hormones are thyroid hormones?
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Amine
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What is the Special property of amine hormones?
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They're non-polar
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WHat is the main method of peptide synthesis?
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The use of inactive precursor hormones and cleavage
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All cholesterol derived hormones are:
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steroids
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What is an example of angiotensin hormone synthesis?
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Angiotensin-Renin-ANG I-ACE-Ang II-target
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Where do G Proteins get their name?
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they utilize GTP (similar to ATP)
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What is a a primary messenger and what is a intracellular messenger?
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A hormone and an intracellular molecule
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What do G Proteins stimulate?
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AC or DAG
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What do AC or DAG do?
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induces 2ndary messenger (either intraC Ca2+ or cAMP)
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What are the steps in lipophilic hormone action?
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Free Hormone enters target cell, binds to hormone receptor in cell nucleus which contains a hormone response element (a piece of DNA), the HRE stimulates mRNA which then results in protein synthesis, and the protein then has a physiological response
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The anterior pituitary releases:
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Oxytocin and Vasopressin
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What is a tropic hormone and where is it usually released?
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A hormone that stimulates the production of another hormone; in the hypothalamus
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What is the stalk that connects pituitary to hypothalamus contain?
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Blood vessels and axonal fibers
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In the hypothalamus/pituitary system, what happens?
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the hypothalamus synthesizes hormones, they get moved via axons down the stalk to the pituitary which actually releases the hormone
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Which of the 2 pituitary portions is considered a single unit with the hypothalamus?
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Posterior
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What structures synthesize oxytocin and vasopressin (ADH), respectively?
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Paraventricular nucleus (PVN) and Supraoptic Nucleus (SON)
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The link between hypothalamus and AP is called what?
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Hypothalamic-hypophyseal
portal system |
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TRH or Thyrotropin-releasing hormone does what?
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Flows from the hypothalamus to the AP to release TSH and prolactin.
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How is cortisol released?
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ACTH release is activated by the release of CRH which acts on the adrenal cortex which releases cortisol
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Temporal lobe is responsible for:
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auditory processing, speech, and memory formation
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The tropin for LH and FSH is:
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GNRH
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What hormones are released in the AP?
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TSH, ACTH, Prolactin, HGH, FSH, LH
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