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59 Cards in this Set

  • Front
  • Back
What type of fats are the most atherogenic of the saturated fatty acids?

What type of foods are these fats found in?
Smaller carbon chain saturated fatty acids:
1. Lauric acid
2. Myristic

*Found in dairy
Which fatty acid should be a target of fat reduction in the diet-- stearic or palmitic acid?
Palmitic acid should be reduced.
(Stearic acid is not a good target for reduction)
What type of food is palmitic acid found in?
Pork and other meats

*Palmitic acid should be a target for reduction in diet
What type of food is stearic acid found in?

How does this fatty acid affect serum cholesterol?
Beef and dark chocolate

*Does not affect serum cholesterol levels much at all
How much meat does the American Heart Association recommend eating each day?
No more than 6 oz. per day
(lean meat, poultry, fish, or seafood)
How are trans fatty acids produced?
During the hydrogenation process to convert liquid vegetable oils into a solid fat
How does the consumption of trans fats increase the risk of heart disease?
By increasing LDL and total cholesterol
(may also lower HDL cholesterol levels)
Most fat in the diet should come from what sources?
Monounsaturated and polyunsaturated fats
(fish, nuts, seeds and vegetable oils)
What type of oil should be used to maintain a healthy diet?
Unhydrogenated oils
(canola, safflower, sunflower, or olive oil)
What is the monounsaturated fatty acid in the diet?
Oleic acid
What is the effect of monounsaturated fat on cholesterol?
Reduces LDL and total cholesterol (without affecting HDL cholesterol)
**Reduces risk of heart disease
What fraction of your fat intake should come from monounsaturated fats?
About 1/3
List 4 common sources of monounsaturated fats.

Which of these is the lowest in saturated fat?
1. Olive oil
2. Avocado
3. Peanut oil
4. Canola oil

*Canola oil is the lowest in saturated fat, making it a common recommendation by many dietitians
What is the principle polyunsaturated fat in the diet?
Linoleic acid
What is the effect of polyunsaturated fats on cholesterol?
Lower LDL, total cholesterol, and HDL cholesterol

*Therefore, they are considered NEUTRAL in affecting heart disease

(Compare this to monounsaturated fats which lower LDL and total cholesterol, without affecting HDL cholesterol ---> lowers risk of heart disease)
List 4 primary dietary sources of polynsaturated fats.
1. Corn oil
2. Safflower oil
3. Sunflower oil
4. Soybean oil
How do omega-3 fatty acids reduce the risk of heart disease?
1. *Reducing blood-clotting
2. Reducing serum total and LDL cholesterol levels
What are the most important omega-3 fatty acids?

In what foods are these found?
1. Eicosapentanoic acid (EPA)
2. Docosahexanoic acid (DHA)

*Cold water (sea) fish
Which fatty acid is an omega-6 fatty acid?

What is it synthesized from?
Arachadonic acid (20:4)

*Synthesized from linoleic acid (essential fatty acid)
Arachadoni acid is the precursor of what biological compounds?
1. Prostaglandins
2. Thromboxanes
(20 carbon compounds collectively referred to as eicosanoids)
What is the effect of PGF2alpha?

What is the precursor of this prostaglandin?
1. Increases vasoconstriction
2. Increases smooth muscle contraction

*Synthesized from arachadonic acid
What is the primary thromboxane produced by arachadonic acid?

What is its function?
TXA2

1. Increases vasoconstriction
2. Increases platelet aggregation in blood clotting
Consumption of the omega-3 fatty acids found in fish (EPA and DHA) increases the synthesis of which prostaglandin and thromboxane?
1. PG13
2. TXA3
How does the function of TXA3 compare to that of TXA2?
TXA3 is much less effective at vasoconstriction and platelet aggregation than TXA2
List 4 primary dietary sources of polynsaturated fats.
1. Corn oil
2. Safflower oil
3. Sunflower oil
4. Soybean oil
What is the function of PG13?
Vasodilation
How do omega-3 fatty acids reduce the risk of heart disease?
1. *Reducing blood-clotting
2. Reducing serum total and LDL cholesterol levels
What are the most important omega-3 fatty acids?

In what foods are these found?
1. Eicosapentanoic acid (EPA)
2. Docosahexanoic acid (DHA)

*Cold water (sea) fish
Which fatty acid is an omega-6 fatty acid?

What is it synthesized from?
Arachadonic acid (20:4)

*Synthesized from linoleic acid (essential fatty acid)
Arachadoni acid is the precursor of what biological compounds?
1. Prostaglandins
2. Thromboxanes
(20 carbon compounds collectively referred to as eicosanoids)
What is the effect of PGF2alpha?

What is the precursor of this prostaglandin?
1. Increases vasoconstriction
2. Increases smooth muscle contraction

*Synthesized from arachadonic acid
What is the primary thromboxane produced by arachadonic acid?

What is its function?
TXA2

1. Increases vasoconstriction
2. Increases platelet aggregation in blood clotting
List 4 primary dietary sources of polynsaturated fats.
1. Corn oil
2. Safflower oil
3. Sunflower oil
4. Soybean oil
Consumption of the omega-3 fatty acids found in fish (EPA and DHA) increases the synthesis of which prostaglandin and thromboxane?
1. PG13
2. TXA3
How do omega-3 fatty acids reduce the risk of heart disease?
1. *Reducing blood-clotting
2. Reducing serum total and LDL cholesterol levels
How does the function of TXA3 compare to that of TXA2?
TXA3 is much less effective at vasoconstriction and platelet aggregation than TXA2
What are the most important omega-3 fatty acids?

In what foods are these found?
1. Eicosapentanoic acid (EPA)
2. Docosahexanoic acid (DHA)

*Cold water (sea) fish
What is the function of PG13?
Vasodilation
Which fatty acid is an omega-6 fatty acid?

What is it synthesized from?
Arachadonic acid (20:4)

*Synthesized from linoleic acid (essential fatty acid)
Arachadoni acid is the precursor of what biological compounds?
1. Prostaglandins
2. Thromboxanes
(20 carbon compounds collectively referred to as eicosanoids)
What is the effect of PGF2alpha?

What is the precursor of this prostaglandin?
1. Increases vasoconstriction
2. Increases smooth muscle contraction

*Synthesized from arachadonic acid
What is the primary thromboxane produced by arachadonic acid?

What is its function?
TXA2

1. Increases vasoconstriction
2. Increases platelet aggregation in blood clotting
Consumption of the omega-3 fatty acids found in fish (EPA and DHA) increases the synthesis of which prostaglandin and thromboxane?
1. PG13
2. TXA3
How does the function of TXA3 compare to that of TXA2?
TXA3 is much less effective at vasoconstriction and platelet aggregation than TXA2
What is the function of PG13?
Vasodilation
What is the overall effect of increasing consumption of omega-3 fatty acids?
1. Decrease vasoconstriction
2. Decrease platelet aggregation

*Reduced risk of heart disease
Since eicosapentoic acid and docosahexanoic acid can be synthesized from linolenic acid, can adequate omega-3 fatty acids by achieved by de novo synthesis?
NO. This is an incorrect assumption
*Generally the conversion of linoleic acid to EPA and DHA is an inefficient conversion.

So, individuals should consume fish about twice a week
Will cholesterol consumption increase serum total and LDL cholesterol levels to the same extent as saturated fat and trans fat?
NO.
Cholesterol will increase these levels, but not the the extent that saturated and trans fats do.
What are some common cholesterol-containing foods?
1. Whole eggs
2. Shellfish
3. Organ meats (liver)
4. Whole milk
What is the dietary recommmendation for cholesterol consumption?
Less than 300 mg per day
What amount of body fat is present in men and women who are defined as "obese?"
Men --> 19% body fat
Women --> 26% body fat
How can you calculate BMI?
body weight (kg)/ height (m^2)

body weight (lbs)/ height (in^2) x 703
What are some risks associated with obesity?
1. Shorter life span
2. Heart disease
3. Diabetes
4. Cancer
Compare the metabolic effect of high fat intake with high carbohydrate intake.
High fat intake does not stimulate fat oxidation like an increase in carbohydrate intake stimulates carboydrate oxidation

*This might explain higher fat storage with a high fat intake
What is the "snack well syndrome?"
Used to describe the phenomenon that people will gain weight from over-eating low-fat items
*These are high-energy dense foods, leading to increased caloric intake
What are the primary low-energy dense foods?
High water, high fiber foods:

1. Fruits
2. Vegetables
3. Watery soups
What is NEAT?

What are some examples?
Non-Exercise Activity Thermogenesis

*Caloric expenditure not associated with intentional activity

1. Pacing
2. Fidgeting
3. Squirming in your seat
What type of energy expenditure will increase most in response to overeating? (occurs in individuals most resistant to weight gain)
NEAT
Non-Exercise Activity Thermogenesis
What type of exercise is recommended for weight loss?
moderate/low intensity
30-60 min/day, at least 5 days/week