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23 Cards in this Set

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What is the diagnostic criteria for DM based on fasting plasma glucose, casual glucose, and 2 hr plasma glucose after 75 gram glucose load?
FPG >120 mg/dL
Casual plasma glucose >200 mg/dL
2hr plasma glucose >200 mg/dL after 75 gm glucose load
What are the impaired fasting glucose and impaired glucose tolerance ranges for pre-diabetes?
Impaired fasting glucose (IFG) : >70 and <126 mg/dL

Impaired glucose tolerance (IGT) 2hr PG: >140 and <200
List 3 markers of immune destruction seen that may be detected in T1DM.
1. ICA- islet cell autoantibodies
2. IAA- autoantibodies to insulin
3. GAD 65- autoantibodies to glutamic acid decarboxylase
T1DM has a strong genetic association with which HLA genes?
DQA and DQB
How does the rate of B cell destruction differ between children and adults with T1DM?
Rapid in infants and kids
Slower in adults
What's the difference between Type 1A DM and Type 1B?
Type 1A: immune-mediated destruction of beta cells, ICA (+)
Type 1B: beta cells are destroyed by another mechanism, ICA (-)
What group of individuals are more prone to T1DM?
Caucasians
List 5 autoimmune diseases that are associated with T1DM.
1. Graves hyperthyroidism
2. Hashimotos hypothyroidism
3. Addison's disease
4. Vitiligo
5. Pernicious anemia
At what age should asymptomatic, undiagnosed individuals be tested for DM?

When should you test someone who is younger?
Over 45 yo (repeat test every 3 years)

Test someone who is younger if their BMI >25
At which HDL and Triglyceride levels should you test someone for DM?
HDL <35
Trig >250
How many months of glycemic control does an A1C test reflect?
2-3 months
What A1C value reflects adequate glycemic control? (ADA standard of care)
= or <7%
What pre-prandial blood glucose level reflects adequate glycemic control? (ADA standard of care)
Pre-prandial BG 70-130
What post-prandial blood glucose level reflects adequate glycemic control?
Post-prandial BG <180
How often should you perform an A1C test for a DM patient?
2 x per year if at goal
4 x per year if therapy is changed or not at goal
How often should you measure BP for a DM patient? What is the goal?
Measure at every visit
Goal: <130/80
How often should you perform a lipid profile on a DM patient? What are the goal values?
Annually
LDL <100, Trig <150, HDL >40
When should diabetes patients be treated for cardiovascular prevention?

At what age should they not be treated?
Treat if:
>40 yo and have one or more CV risk factors
Consider between 30-40 if CV risk factors are present

Don't treat if < 21 yo
How often should you test for microalbuminuria?
Annually
(spot albumin to creatinine ratio)
How often should you test for diabetic retinopathy?
T1DM: within 3-5 years of diagnosis and then annually
T2DM: shortly after diagnosis and then annually
How often should a comprehensive foot examination be performed for a DM patient?
annually
What should you check at every visit with a DM patient?
1. Blood pressure
2. Weight
List 4 exams that you should perform annually on a diabetes patient.
1. Dilated eye exam
2. Foot exam
3. Lipid profile
4. Microalbuminuria