Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
9 Cards in this Set
- Front
- Back
|
Mutant organisms that has lost the ability to make an essential nutrient/metabolite
|
Autotrophs
|
|
|
Aerobic mechanims to obtain iron
|
Siderophores
Iron-regulatable OM proteins Host iron-binding proteins: transferrine, lactoferrin, hemoglobin, etc. |
|
|
GSP
|
-Targets: proteins to CM + beyond
-Apparatus: Sec B grabs SS and brings to sec A, thru translocon (secYEG) -N-terminal ss, cleaved by Lep -Post-translational -Uses ATP hydrolysis |
|
|
SRP
|
-Targets proteins to CM
-Apparatus: ss+mRNA+ribosome+SRP comes to CM -ss not cleaved by Lep -co-translational -Uses GTP hydrolysis |
|
|
-Secretion signal c-terminus
-Uses ATP -GSP or SRP not used -Involves ABC |
Type I secretion
|
|
|
1. Cross the cytoplasmic membrane
-protein recognized by GSP -Protein processed, folded in periplasmic space -Cross the OM -Structurally similar to type IV pili |
Type II (2-step secretion)
|
|
|
Inner membrane
-Outer membrane -Eukaryotic host CM -Contact dependent (activated w/ contact by host) -No sec, no signal sequence |
Type III (contact dependent)
|
|
|
-Conjugal transfer
-Used for proteins, DNA, both -Pilus-like structure -Agrobacterium system sec-independent -Pertussis toxin uses Sec to get to periplasm, then type IV to get across OM |
Type IV (conjugal transfer)
|
|
|
-N terminal ss recognized by GSP
-Sec B binds to protein & transports into periplasmic space -ss cut off by Lep -2 regions formed: 1. C-terminal domain forms secretion pore in OM 2. Released portion detaches by autoproteolysis |
Type V (autotransporters)
|
