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4 Cards in this Set
- Front
- Back
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Childhood Vesicular Exanthems
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Diffuse skin rashes with vesicles, tissue damage is due to viral replication within the target endothelial cells
Chicken Pox/Shingles, Small Pox, Hand/Foot/Mouth |
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"Chicken Pox"- (Varicella-Zoster Virus)
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(Herpesviridae, ds DNA with envelope)- Itchy, Asynchronus vesicular rash that begins in face and trunk and spreads outwards; Transmitted by Resp/Lesion Fluid;
Lifetime infection with latent Virus in DRG that may be reactivated and cause Shingles(a unilateral dermatomal asynchronus vesicular rash that is itchy and extremely painful; vesicles scab over in 7-10d and resolve 2-4w- Tx for pain). Infants at significant risk if mother develops varicella 5d pre to 2d post-partem; Mother will not have time to produce and transmit antibodies; Varicella Vx available. Dx: IgM/Serology, Syncytia, “Dew Drop on Rose Petal” |
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"Small Pox"- (Variola Virus)
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(Poxviridae ds DNA w/ double env, cytosolic replication): Synchronous vesicular rash that starts on face and distal extremities and moves inward. Transmitted by Resp/Lesion Fluid; resolves ~14d,
Variola Vx Available. Dx: IgM/Serology, Guarnieri Bodies |
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"Hand/Foot/Mouth"- Coxsackie A16 Virus
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(Picornuviridae ss+ RNA, -env): Vesicular lesions to hands/feet/mouth, possible lesions to the anus from loose stool and virus shedding; Transmitted Fecal-Oral/Resp/Lesion Fluid; Resolves in 1-5d,
No Vx Available. Dx: IgM/Serology |
