Mm B-3 Childhood Non-Vesicular Exanthems

Front 1

CHILDHOOD Non-Vesicular EXANTHEMS

Back 1

-Diffuse macular/popular skin rashes without vesicles

Front 2

"Scarlett Fever" (S. Pyogenes)




(Presentation? Specific skin signs? Tx/Sequellae? Damage?)

Back 2

(GAS, g+ diplococci in chains):
-Hyaluronidase/Streptolysin S/Streptodornase

Blanching macule/popular rash starting in the trunk, Tissue damage due to (DTH) Delayed Type Hypersensitivity to Erythropoetic toxin on bacteriophage. Often post-throat infection, spread via respiratory; Poss PSGN/ARF

Dx: Pastia Lines, Sandpaper Texture, Strawberry Tongue

Tx: Beta Lactams

Front 3

"Measles"- (Rubeola Virus)


(Presentation? Specific signs? Resolution/Sequellae? Damage?)

Back 3

(Paramyxoviridae ss- RNA, +env):

Macule/Papular coalescing rash with HIGH fever and 4 C’s Coryza/Conjunctivitis/Cough/Copliks Spots; Infection following or transmitted via Respiratory; damage due to CTL’s attacking the infected cells; Possible development of SSPE Subacute Sclerosing Panencephalopathy 1-10y down the road; Lasts 7d,

Vx-MMR

Dx: Igm/Serology

Front 4

"Rubella"- (Rubella Virus)




(Presentation? Specific signs? Resolution/Sequellae? Damage-results?)

Back 4

(Togaviridae ss+ RNA, +env)

Macule/Papular NONCOALESCING rash with LOW fever, Damage due to Immune Complexes and may show polyarthralgia; Spread via respiratory/transplacental; Risk of congenital rubella-Teratogenic (Abortion/deformities); Lasts 3d,

Vx-MMR

Dx: IgM/Serology

Front 5

"Slap Cheek"-Erythema Infectiosum (ParvoB19 Virus)




(Presentation? Specific signs? Resolution/Sequellae(tropism)? Damage-results?)

Back 5

(Parvoviridae +/-ss, -env)

Macule/Papule rash to the cheeks that spreads diffusely as a lacy-ribbon like rash; Virus has tropism for P-Globoside antigen on erythroid precursors may see drop in hematocrit/anemia or presence of pronormoblasts, Transmitted via Resp/Transplacental, Poss Hyprops Faetalis;

no Vx.

Dx: IgM/Serology, Pronormoblasts present, anemia/decreased hematocrit

Front 6

HHV6 (Herpesviridae)

Back 6

(Herpesviridae ds DNA, +env)

3-5d Hx of High Fever followed by Macule/Papular “Rosy” rash to face and trunk, virus replicates in T/B and oropharynx cells, may lay latent in DRG and is transmitted via respiratory.

Dx: IgM/Serology