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34 Cards in this Set
- Front
- Back
sensory innervation of the breast |
anterior and lateral cutaneous branches of the 4th-6th intercostal nerves (ventral rami of T4-T6) |
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sympathetic innervation of the breast |
reach the blood vessels, glandular tissue, and smooth muscles by way of 2nd -6th intercostal nerves |
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fetal development of breasts |
mammary ridges on either side of the body from the arms to the legs; starting in the 6th week there is the formation of a primary bud which grows secondary buds and then a mammary pit forms and lactiferous ducts are formed |
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amastia |
lack of breasts (if the mammary ridges disappear) |
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polymastia |
many breasts; if the mammary ridge forms an accessory breast at an additional location on the mammary ridges |
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athelia |
one nipple; if one less nipple forms |
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polythelia |
many nipples; if an additional nipple forms along the line of the mammary ridge |
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unilateral hypoplasia |
if one breast is a lot smaller (15% less or more) than the other (may impede function in that breast) |
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gynecomastia |
breasts in a man; associated with obesity; can lead to breast cancer in men; can be due to hormonal imbalances due to testicular cancer, suprarenal cancer, or cirrhosis |
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the breasts at puberty |
ovarian hormones induce growth; the ductile system grows primarily from estrogen and the lobular system grows primarily from progesterone |
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at the end of puberty the brest is |
1/3 mammary gland, 1/3 fat, and 1/3 connective tissue |
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the breasts during pregnancy |
additional growth of breast under influence of pituitary, ovarian/placental hormones; ductile system grows due to prolactin and estrogen; progesterone at this stage inhibits lactation |
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at the end of pregnancy the breast is |
40-50% ductile system |
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lactation in the breast |
estrogen and progesterone levels decrease rapidly; progesterone is no longer inhibiting lactation; with suckling (or thoughts of baby) prolactin levels (milk production) and oxytocin levels (letdown) temporarily spike |
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menopause on the breast |
estrogen and progesterone levels drop, leading to delimitation of the entire ductile system, causing the remnants to resemble connective tissue; testosterone (ovarian) levels increase; endogenous aromatase in the breast can convert testosterone to estrogen in the breast- an uptick in hormone sensitive cancer in the elderly and use of estrogen receptor blockers or aromatase inhibitors with active research ongoing as regarding side effects |
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symptoms of breast cancer |
lumps within tissue (andenocarcinomas), peau d'orange (edema of the skin), dimpled skin/inverted nipple, elevation of breast with exercise (signaling something (cancer) connecting the breast with the pec muscle |
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risk factors for breast cancer |
heredity, age, environmental factors, and age |
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heredity on breast cancer |
BRCA1 and BRCA2 are the most well-known factors; at least a dozen other genes have been identified (many of which can co-occur as gene complexes) (with as yet poorly understood interactions); gene screening is expensive and often uncovered |
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age on breast cancer |
by 30 1 in 2500, by 40 1 in 250, by 70 1 in 25; ultimately 1 out of 8 |
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environmental facts and breast cancer |
estrogen mimics, general risks |
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hormone replacement therapy on breast cancer |
estrogen mimics |
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treatment of breast cancer |
ranges from lumpectomy (localized excision followed by drug and radiation therapy to prevent redevelopment of cancer) to simple single or simple double mastectomy followed by drug and radiation therapy to radical single or double mastectomy followed by extremely aggressive drug and radiation therapy (extremely rare) |
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clinical examination of thorax |
inspection- visual, look for abnormalities, asymmetries; palpation- feel for bumps, areas of tenderness; percussion- listen for dullness (lack of tympanic sounds) over lungs; auscultation- listen for breathing sounds and to the heart |
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classification of ribs |
by type- true (1-7), false (8-10), or floating(11-12); by form- typical (3-10) or atypical (1, 2, 11, 12); by clinically- normal or anomalous (extra rib) |
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a dislocated rib versus a separated rib |
dislocated= costal cartilage from sternum; separated= rib from costal cartilage |
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the danger of an extra cerc=vical rib |
can compress rivers of inferior trunk of brachial plexus leading to pain in upper limb (one example of thoracic outlet syndrome) |
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the danger of an extra lumbar rib |
can be mistaken for a fractured rib or lead to mistakes in counting vertebra |
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muscles of the thorax that aid in protection of the thorax and inspiration |
serratus posterior superior, serratus posterior inferior, levatores costarum, intercostals, subcostals, and transversus thoracis |
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muscles not truly of the thoracic cage but do serve a protective role OR air in forced inspiration |
trapezius, lat dorsi, rhomboid major and minor, pectorals major and minor, serratus anterior, subclavius, scalenes |
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blood supply to the thorax |
subclavian artery via supreme intercostal to posterior intercostals 1 and 2; thoracic aorta to posterior intercostals 3-11 and subcostal; internal thoracic artery to anterior intercostals 1-6 and, via musculophrenic, to anterior intercostals 7-9; axillary artery to superior thoracic and lateral thoracic |
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innervation of thoracic cage |
intercostal nerves (ventral rami of T1-T11 spina lnerves); subcostal nerve (ventral rami of T12 spinal nere); typically run inferior to their associated rib- inferior to the associated artery which is, in turn, inferior to the associated vein (VAN) |
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the intercostal/subcostal nerves |
typically provide sensory innervation, along with associated dorsal rami, from a dermatome that rings the body - above and below a line defined by the nerve in question, there is overlap and a need to deaden adjacent intercostal nerves in order to deaden any given intercostal space; provide muscular branches of the thoracic cage; provide, by way of fibers from the sympathetic trunk, sympathetic innervation to the blood levels, glands, and smooth muscles of the thoracic cage |
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the VAN positioning |
initially centered in the intercostal space as they exit the spinal column; soon move to a position in the costal groove along the lower edge of the superior rib (so enter just superior to a rib when doing surgery) |
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during a mastectomy what do you have to watch out for |
the long thoracic nerve (which you want to avoid) and the lateral thoracic artery (which you have no choice but to remove) |