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11 Cards in this Set
- Front
- Back
antimicrobials that are protein synthesis inhibitors |
buy AT 30, CCEL at 50; 30S= Aminoglycosides (bacteriCIDAL), Tetracyclines (static); 50S=Chloramphenicol (static), Clindamycin (static), Erythromycin (macrolides)(static), and Linezolid (variable) |
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the beta lactamase inhibitors |
CAST; Clauvanic Acid, Sulbactam, Tazobactam |
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the aminoglycosides and their toxicity |
mean GNATS canNOT kill anaerobes; Gentamycin, Neomycin, Amikacin, Tobramycin, Streptomycin; toxicity= Nephrotoxicity, Ototoxicity, Teratogen |
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macrolides |
macroSlides ACE it; ACE= Azithro-, Clarithro-, and Erythro-mycin; they inhibit protein synthesis by blocking translocation 'sliding' |
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trimethoprim side effects |
TMP treats marrow poorly= side effects of megaloblastic anemia, leukopenia, and granulocytopenia |
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treatments for TB |
RIPE= Rifampin, Isonizid, Pyrazinamide, Ethambutol |
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bactericidal antibiotics |
Very Finely Proficient At Cell Murder; Vancomycin, flyoroquinolones, PCN, aminoglycosides, cephalosporins, metronidazole |
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the fluoroquinolones |
all end in floxacin; ciprofloxacin, levofloxacin, moxifloxacin |
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isoniazid toxicity mneumonic |
INH=Injures Neurons and Hepatocytes; neurotoxicity, hepatotoxicity, lupus |
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what are rifampin's 4 Rs? |
RNA polymerase inhibition, Revs up microsomal P-450, Red/orange body fluids, Rapid resistance if used alone |
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NAVIR TEASE a proTEASE |
all protease inhibitors end in -navir |