Mixed Pharm

Front 1

Combination of mixing Lasix and Digoxin in rx of CHF.

Back 1

Lasix will increase the cardiac toxicity of Digoxin.

Front 2

Propranol with nitroglycerin to rx angina for what reasons?

Back 2

1.block excess tachycardia
2.decrease work of myocardium.
3.reduce O2 consumption of myocardium.
4.increase collateral circulation

(does not increase left ventricular end diastolic volume).

Front 3

What drug antagonizes the vasodilating and brochodilating actions of Proternol?

Back 3

Cromolyn Sodium.

Front 4

Which drug is both alpha and beta adrenergic receptor blockers (in rx HTN)?

Back 4

Labetalol.

Front 5

Which anti-convulsant drug causes ataxia, nystagmus, and vertigo as SE?

Back 5

Tegretol.

Front 6

MOA of Terbutaline?

Back 6

Beta 2 agonist.

Front 7

What's another alternative to rx Herpes simplex?

Back 7

Vidarabine.

Front 8

What's the main adverse effect of Erythromycin?

Back 8

Cholestatic hepatitis.

Front 9

Rx of Pseudomonas aeruginosa?

Back 9

Cefoperazone.

Front 10

MOA of cyclophosphamide?

Back 10

Alkylating agent.

Front 11

Alternative drug to rx N.Gonorrhea in patients allergic to penicillin?

Back 11

Spectinomycin.

Front 12

Bethanechol can result in _____?

Back 12

aggravation of peptic ulcer.

Front 13

Effects of propranolol?

Back 13

Blockers that dilates arterioles and venules.

Front 14

SE of doxycycline?

Back 14

Photosensitivity rash.

Front 15

Limited use of what anti-convulsive drug b/c due to its hepatotoxicity?

Back 15

Valproic acid.

Front 16

Drugs that have increased sympathetic activity and reflex tachycardia as SE?

Back 16

Nitroglycerine, diazoxide, hydralazine, minoxidil. (Not clonidine).

Front 17

Penicillinase producing Staph infection can be treated by?

Back 17

Nafcillin.

Front 18

When using vincristine, patient should be monitored for?

Back 18

Neurotoxicity.

Front 19

What's a good drug both treating HTN and vasospastic angina?

Back 19

amoldipine (Ca channel blocker)

Front 20

What's the major SE of digoxin toxicity?

Back 20

Cardiac and CNS adversities: bradycardia, delirium, hallucination, visual disturbances (yellow vision), atrial fibrillation (partial AV block).

Front 21

SE of Lovastatin (HMG-CoA reductase)?

Back 21

Diffuse muscle pain and weakness. Elevated serum creatine kinase level.

Front 22

Antiarrhythmic of choice for most acute supraventricular tachycardia?

Back 22

Adenosine.

Front 23

Which drug causes hemorrhagic cystitis?

Back 23

Cyclophophamide.

Front 24

What first-line TB drug could interfere w/ effective levels of HIV drugs usch as protease inhibitor?

Back 24

Rifampin (induces metabolism of several other drugs)

Front 25

Risk of kerosene OD?

Back 25

Pulmonary toxicity (b/c kerosene have low viscosity and surface tension properties--> move over the tissue surface and move up the esophagus and may enter lung).

Front 26

Clinical picture of aspirin OD?

Back 26

Metabolis acidosis, respiratory alkalosis, dehydration, hyperventilation, hyperthermia.

(salicylates uncouple oxidative phosphorylation-->energy that normally would be converted to ATP is lost as heat. Respiratory alkalosis is compenstaed by renal loss of bicarbonate. Salicylates result in formation of lactic and pyruvate--> metabolic acidosis.)

Front 27

DOC for bacteroides fragilis.

Back 27

Metronidazole.

Front 28

DOC for Bordetella pertussis.

Back 28

Erythromycin.
Acellular pertussis vaccine (at 2, 4, 6 months).

Front 29

DOC for Borrelia burgdorferi (3).

Back 29

Doxycycline, Penicillin G, ceftriaxone.

Front 30

DOC for Chlamydia psittaci.

Back 30

Tetracycline.

Front 31

DOC for Chlamydia trachomatis (2).

Back 31

Tetracycline, erythromycin.

Front 32

DOC for clostridium difficile.

Back 32

Vancomycin, metronidazole.

Front 33

DOC for clostridium tetani.

Back 33

Toxoid vaccine (2, 4, 6, 18 months). Booster every 10 yrs. Penicillin.

Front 34

DOC for Corynebacterium diphtheriae.

Back 34

Penicillin. Erythromycin.
Inactivated toxoid vaccine.
Antitoxin (neutralized unbound toxin).

Front 35

DOC for Coxiella burnetti.

Back 35

Tetracycline.

Front 36

DOC for Enterococci faecalis.

Back 36

Penicillin and an aminoglycoside.
Vancomycin.

Front 37

DOC for E.Coli.

Back 37

UTI: ampicillin or sulfonamides, TMP-SMX.
Sepsis: Aminoglycoside + 3rd gen cephalosporins.
Neonatal meningitis: ampicillin + cefotaxime.
Traveler's diarrhea: rehydration.

Front 38

DOC for Gardnerella vaginalis.

Back 38

Metronidazole.

Front 39

DOC for Haemophilus ducreyi.

Back 39

Nafcillin. Erythromycin. Tetracycline.

Front 40

DOC for Haemophilus influenzae.

Back 40

Hib vaccine (B type capsule cnjugated to diphtheria toxoid as a carrier protein).
Ceftriaxone.
(household contacts rx w/ rifampin for meningitis prophylaxis)
Ampicillin.

Front 41

DOC for Helicobacter pylori.

Back 41

Triple therapy.
(1) amoxicillin, metronidazole, bismuth.
(2) amoxicillin, omeprazole, ranitidine.

Front 42

DOC for Klebsiella pneumoniae.

Back 42

Cephalosporins.

Front 43

DOC for Legionella pneumophila.

Back 43

Erythromycin.

Front 44

DOC for Listeria monocytogenes.

Back 44

Ampicillin.

Front 45

DOC for Bacillus anthracis.

Back 45

Ciprofloxacin.

Front 46

DOC for mMycobacterium avium-intracellulare (MAC).

Back 46

Amikacin + doxycycline.

Front 47

DOC for Mycobacterium leprae.

Back 47

Dapsone and rifampin for tuberculoid form.
Clofazamine, dapsone, rifampin for lepromatous form.
2 yr rx.

Front 48

DOC for Mycobacterium tuberculosis.

Back 48

Isoniazid, rifampin, pyrazinamide for 6-9 months.

Front 49

DOC for Mycobacterium pneumonia.

Back 49

Erythrymycin.

Front 50

DOC for Neisseria gonorrhoeae.

Back 50

Erythromycin or silver nitrate in neonates.
Ceftriaxone; spectinomycin and tetracyclne.

Front 51

DOC for Neisseria meningitidis.

Back 51

Rifampin, penicillin G,

Front 52

DOC for Nocardia asteroides.

Back 52

Sulfonamides.

Front 53

DOC for Pseudomonas aeruginosa.

Back 53

Aminoglycoside or 3rd gen cephalosporin.
Penicillin + pipercillin + aminoglycoside.

Front 54

DOC for Rickettsia prowazeki, rickettsii, typhi.

Back 54

Tetracycline.

Front 55

DOC for Shigella.

Back 55

Ampicillin.
3rd gen cephalosporin,
TMP-SMX.
quinolone.

Front 56

DOC for Staph aureus.

Back 56

Vancomycin (MRSA),
Cephalosporin,
Methicillin

Front 57

DOC for Campylobacter jejuni

Back 57

Erythromycin

Front 58

DOC for Salmonella typhi.

Back 58

Chloramphenicol,
ceftriaxone

Front 59

DOC for Staph epidermidis.

Back 59

Vancomycin.

Front 60

DOC for Staph saprophyticus.

Back 60

Quinolones.
TMP-SMX.

Front 61

DOC for Strep agalactiae

Back 61

(Group B strep)
Ampicillin before delivery.
Penicillin G.

Front 62

DOC for Strep pneumoniae.

Back 62

Penicillin and erythromycin.
Intermediate resistance: ceftriaxone.
Highly resistant: vancomycin.

Front 63

DOC for Strep pyogenes.

Back 63

Penicillin G. If allergic, use erythromycin.

Front 64

DOC for Treponema pallidum.

Back 64

Penicillin.

Front 65

DOC for Trpheryma whippelli.

Back 65

TMP-SMX.

Front 66

DOC for Vibrio cholerae.

Back 66

Rehydration, tetracycline.

Front 67

DOC for Yersinia pestis.

Back 67

Streptomycin/ tetracycline.

Front 68

DOC for Chlamydia pneumonia.

Back 68

Tetracycline.

Front 69

DOC for Proteus.

Back 69

TMP-SMX.

Front 70

DOC for Strep viridan.

Back 70

Penicillin.