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28 Cards in this Set

  • Front
  • Back
Chromosomes
DNA + protein mixed, 1:1 ratio
thread like struct
Protein in chromosomes?
mostly histones
Euchromatin
loosely packed, easy to uncoil and transcribe
Heterochromatin
condensed, easy to see
Centromeres
spindle attachment point
telomeres
end of chromosome
examples of heterochromatin
centromeres, telomeres
Chromosome structure:

metacentric
centromere in middle
Chromosome structure:

submetacentric
centromere between middle and near end of chromosome
Chromosome structure:

acrocentric
centromere near end of chromosome
Chromosome structure:

telocentric
centromere at end of chromosome
C banding
detects heterochromatic regions,
Giemsa - staining
C banding was developed by
Pardue and Gall
Karyotype
complete set of metaphase chromosomes in a cell
Karyotype - why metaphase
most condensed, easiest to see after staining
Which chromosome is #1?
The largest
M phase
mitotic phase, mitosis + cytokinesis
Cytokinesis
division of cytoplase
Interphase
stage between mitotic division, includes G1, S1, G2
G1
early cell growth, slow
G0
some cells enter after G1
S1
DNA synthesis, slow, replication of chromosomes into sister chromatids
G2
Growth, organelles get ready for mitosis, short
During G2...

the nucleus
is well defined, has membrane
During G2...

nucleoli
one/more are visible (make ribosomes)
During G2...

centrioles
two pairs adjacent to nucleus (formed earlier by replication of original pair),
plural - centrosome
During G2...

microtubules
radiate from centrioles in array (aster)
During G2...

chromosomes
duplicated, not condensed