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31 Cards in this Set

  • Front
  • Back

G2 of Interphase

A nuclear envelope encloses the nucleus.

G2 of Interphase

The nucleus contains one more more nucleoli (singular, nucleolus).

G2 of Interphase

Two centrosomes have formed by duplication of a single centrosome. Centrosomes are regions in animals cells that organize the microtubules of the spindle. Each centrosome contains two centrioles.

G2 of Interphase

Chromosomes, duplicated during S phase, cannot be seen individually because they have not yet condensed.

Prophase

The chromatin fibers become more tightly coiled, condensing into discrete chromosomes observable with a light microscope.

Prophase

The nucleoli disappear.

Prophase

Each duplicated chromosome appears as two identical sister chromatids joined at their centromeres and, in some species, all along their arms by cohesins (sister chromatid cohesion).

Prophase

The mitotic spindle (named for its shape) begins to form. It is composed of the centrosomes and the microtubules that extend from them. The radial arrays of shorter microtubules that extend from the centrosomes are called asters.

Prophase

The centrosomes move away from each other, propelled partly by the lengthening microtubules between them.

Prometaphase

The nuclear envelope fragments.

Prometaphase

The microtubules extending from each centrosome can now invade the nuclear area.

Prometaphase

The chromosomes have become even more condensed.

Prometaphase

Each of the two chromatids of each chromosome now has a kinetochore, a specialized protein structure at the centromere.

Prometaphase

Some of the microtubules attach to the kinetochores, becoming "kinetochore microtubules," which jerk the chromosomes back and forth.

Prometaphase

Nonkinectochore microtubules interact with those from the opposite pole of the spindle.

Metaphase

The centrosomes are now at opposite poles of the cell.

Metaphase

The chromosomes have all arrived at the metaphase plate, a plane that is equidistant between the spindle's two poles. The chromosomes' centromeres lie at the metaphase plate.

Metaphase

For each chromosome, the kinetochores of the sister chromatids are attached to kinetochore microtubules coming from opposite poles.

Anaphase

The shortest phase of mitosis, often lasting only a few minutes.

Anaphase

Begins when the cohesin proteins are cleaved. This allows the two sister chromatids of each pair to part suddenly. Each chromatid thus becomes a full-fledged chromosome.

Anaphase

The two liberated daughter chromosomes begin moving toward opposite ends of the cell as their kinetochore microtubules shorten. Because these microtubules are attached at the centromere region, the chromosomes move centromere first.

Anaphase

The cell elongates as the nonkinetochore microtubules lengthen.

Anaphase

By the end of this stage, the two ends of the cell have equivalent --and complete -- collections of chromosomes.

Telophase

Two daughter nuclei form in the cell.

Telophase

Nuclear envelopes arise from the fragments of the parent cell's nuclear envelope and other portions of the endomembrane system.

Telophase

Nucleoli reappear.

Telophase

The chromosomes become less condensed.

Telophase

Any remaining spindle microtubules are depolymerized.

Telophase

Mitosis, the division of one nucleus into two genetically identical nuclei, is now complete.

Cytokinesis

The division of the cytoplasm is usually well underway bylate telophase, so the two daughter cells appar shortlyafter the end of mitosis.

Cytokinesis

Involves the formation of a cleavage furrow. which pinches the cell in two.