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15 Cards in this Set
- Front
- Back
What makes cartilage?
What makes bone? |
chondrocytes
osteoblasts |
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What two demands must CT reconcile to function normally?
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surround themselves lots of ECM and maintain a way to get food for themselves
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Fibrous, Hyaline, Bone, Elastic : order them from least elastic to most elastic.
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Bone, fibrous, hyalin, elastic
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Differntiate strength and resilience.
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Strength: the capacity of a material to resist force without failure or permanent deformation; Resilience: the capacity of a material to recover its original shape after deformation.
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What happens when force exceeds strength?
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fracture
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Hyaline cartilage
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blueish white, immature bone, Type 2 collagen; epiphyseal plate(where it is responsible for the longitudinal growth
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Elastic cartilage
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Location (Found in structures subjected to repeated deformation or vibration) has perochondrium
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Fibrous catilage
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Type I collagen fibers; Comprises the annulus fibrosus of the intervertebral discs, the cartilage rings surrounding the “sockets” of the shoulder and hip joints, the attachments of tendon to bone, and the articular ends of bones that ossify in mesenchyme; no perichondrium
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Cartilage growth depends on which growth hormone and how does that hormone work?
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Cartilage growth depends mainly on the hypophyseal growth hormone Somatotropin. Somatotropin activates Somatomedin C which acts on chondrocytes
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Which hormones speed up chondrocyte function?
Slow it down? |
Growth hormone, thyroxin, testosterone
Cortisone, hydrocortisone, estradiol |
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Describe basic steps of chrondogenesis
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mesenchyme cells give rise to chondroblasts which act to make chondrocytes which form isogenous groups
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interstitial cartilage growth
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Occurs when chondrocytes divide mitotically into isogenous clusters of daughter cells each secreting a small amount of matrix - epiphyseal plates of long bones, articular cartilage
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Appositional cartilage growth
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Occurs when chondrogenic cells in the inner layer of the perichondrium undergo mitotic division and begin to synthesize matrix. As matrix secretion continues, the chondroblasts drift away from the perichondrium, eventually becoming trapped within matrix lakes of their own manufacture. When matrix secretion subsides, the chondroblasts become mature chondrocytes.
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When does repair of damaged cartilage occur?
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Occurs when chondrogenic cells in the inner layer of perichondrium, or fibroblasts in synovial membrane, are recruited to fill the defect with new tissue
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What is 45% of bone made up of?
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Calcium Hydroxyapatite
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