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15 Cards in this Set

  • Front
  • Back
What makes cartilage?

What makes bone?
chondrocytes

osteoblasts
What two demands must CT reconcile to function normally?
surround themselves lots of ECM and maintain a way to get food for themselves
Fibrous, Hyaline, Bone, Elastic : order them from least elastic to most elastic.
Bone, fibrous, hyalin, elastic
Differntiate strength and resilience.
Strength: the capacity of a material to resist force without failure or permanent deformation; Resilience: the capacity of a material to recover its original shape after deformation.
What happens when force exceeds strength?
fracture
Hyaline cartilage
blueish white, immature bone, Type 2 collagen; epiphyseal plate(where it is responsible for the longitudinal growth
Elastic cartilage
Location (Found in structures subjected to repeated deformation or vibration) has perochondrium
Fibrous catilage
Type I collagen fibers; Comprises the annulus fibrosus of the intervertebral discs, the cartilage rings surrounding the “sockets” of the shoulder and hip joints, the attachments of tendon to bone, and the articular ends of bones that ossify in mesenchyme; no perichondrium
Cartilage growth depends on which growth hormone and how does that hormone work?
Cartilage growth depends mainly on the hypophyseal growth hormone Somatotropin. Somatotropin activates Somatomedin C which acts on chondrocytes
Which hormones speed up chondrocyte function?

Slow it down?
Growth hormone, thyroxin, testosterone


Cortisone, hydrocortisone, estradiol
Describe basic steps of chrondogenesis
mesenchyme cells give rise to chondroblasts which act to make chondrocytes which form isogenous groups
interstitial cartilage growth
Occurs when chondrocytes divide mitotically into isogenous clusters of daughter cells each secreting a small amount of matrix - epiphyseal plates of long bones, articular cartilage
Appositional cartilage growth
Occurs when chondrogenic cells in the inner layer of the perichondrium undergo mitotic division and begin to synthesize matrix. As matrix secretion continues, the chondroblasts drift away from the perichondrium, eventually becoming trapped within matrix lakes of their own manufacture. When matrix secretion subsides, the chondroblasts become mature chondrocytes.
When does repair of damaged cartilage occur?
Occurs when chondrogenic cells in the inner layer of perichondrium, or fibroblasts in synovial membrane, are recruited to fill the defect with new tissue
What is 45% of bone made up of?
Calcium Hydroxyapatite