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118 Cards in this Set

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Minerals
Inorganic elements (non-carbon-containing)

In simplest form possible – are not digested or broken down prior to absorption

Ultimately all minerals come from the environment
Major minerals: required in amounts >100mg/day
Trace minerals: required in amounts <100g/day
Fluids
Substances composed of freely moving molecules

Have the ability to conform to the shape of their container

There are different types of fluids in our bodies
Fluids
50 – 70% of a healthy adult’s body is composed of fluids.

About 2/3 of this fluid is within body cells and is called intracellular fluid.

The remaining 1/3 is extracellular fluid
Extracellular fluids include
Tissue fluid found between the cells within tissues and organs of the body.

Plasma, the fluid portion of blood that carries the blood cells.
The body fluid composition of tissue varies by
Tissue type – lean tissues have higher fluid content than fat tissues

Gender – males have more lean tissue and therefore more body fluid

Age – lean tissue is lost with age and body fluid is lost with it
Body fluid is composed of
Water
Electrolytes: mineral salts dissolved in water, including:
Sodium
Potassium
Chloride
Phosphorus
Electrolytes carry electrical charges:
+Sodium (Na+) and potassium (K+)

- Chloride (Cl-) and phosphorus (HPO42-, phosphate)

Difference in charge is important for the functions that electrolytes are responsible for.
Fluids dissolve and transport substances.
Water is an excellent solvent because it can dissolve many different substances.
Fluids dissolve and transport substances.
The dissolved materials, or solutes, include ions, sugars, amino acids, vitamins, and minerals.
Fluids account for blood volume.
Blood volume is the amount of fluid in the blood.

Increased blood volume can cause blood pressure to rise.

Decreased blood volumes can cause low blood pressure.
Fluids help maintain body temperature.
The high heat capacity of water means that the temperature of our body fluids remains quite stable.
Fluids help maintain body temperature.
Sweating releases heat as the evaporation of water from the skin cools the skin and blood
Fluids protect and lubricate body tissues.
Cerebrospinal fluid protects the brain and spinal column.

Amniotic fluid protects the fetus.

Synovial fluid is a lubricant around joints.

Digestive secretions allow for easy passage of material.
Electrolytes help regulate fluid balance.
Water follows the movement of electrolytes, moving by osmosis to areas where the concentration of electrolytes is high.
Electrolytes help regulate fluid balance.
This allows for the controlled movement of fluids into and out of cells.
Electrolytes help nerves respond to stimuli.
Movement of Na+ and K+ across the membranes of nerve cells changes the electrical charge across the membrane.
Electrolytes help nerves respond to stimuli.
This change in electrical charge carries the nerve impulse along the nerve cell.
Electrolytes signal our muscles to contract.
The movement of calcium (Ca2+) into a muscle cell stimulates the muscle to contract.

The Ca2+ is pumped back out of the cell after the muscle contraction.
Maintaining Fluid Balance
Any water lost from the body must be replaced.

Water is lost through urine, sweat, exhalation, and feces.

Water is gained through beverages, food, and metabolic reactions.
Functions of water
Essential for life
Required for fluid and electrolyte balance and many metabolic reactions
Recommended intake
1.0 to 1.5ml for each kcal expended

Varies with environment, activity level

Drink until your urine is pale yellow.
What if you drink too much water?
Becoming over hydrated is rare
Can result in a dilution of sodium
What if you don’t drink enough water?
Dehydration

Infants and the elderly are especially vulnerable
Functions of sodium
Fluid and electrolyte balance

Associated with blood pressure and pH balance in the body

Required for nerve impulse transmission
Recommended intake
500mg/day is required
Less than 2,400mg/day is recommended
Sources of sodium
Processed foods are surprisingly high in sodium
Deficiency symptoms sodium
Muscle cramps
Hyponatremia – from prolonged vomiting, diarrhea; seen in runners who consume too much water
Excess intake sodium
High blood pressure
Functions of potassium
Fluid and electrolyte balance
Very important in muscle contractions and transmission of nerve impulses
High potassium intake helps to maintain a lower blood pressure
Recommended intake Potassium
2,000 to 4,000 mg/day
Sources of potassium
Processed foods are usually low in potassium
Fresh fruit and vegetables and whole grains are good sources of potassium
Deficiency Symptoms Potassium
Irregular heart beat, loss of appetite, muscle cramps, death
Toxicity Symptoms Potassium
Slowed heart beat
Functions of chloride
Assists with maintaining fluid balance
Assists the immune system
Recommended intake Chloride
Minimum recommendation is 750mg/day
Food sources chloride
Table salt, some vegetables, present in virtually all foods
What if you consume too much chloride?
May lead to hypertension in salt-sensitive patients

No DRI has been set for chloride
What if you don’t consume enough chloride?
This is rare but can occur in people with eating disorders
Disorders related to fluid and electrolyte imbalance include:
Dehydration
Heat stroke
Water intoxication
Hypertension
Neuropsychiatric disorders
Muscle disorders
Dehydration occurs when water loss exceeds water intake.
Commonly due to heavy exercise or high environmental temperatures.

Infants and the elderly are more at risk.
Heat stroke occurs if the body’s temperature regulation mechanisms fail.
Occurs in hot, humid environments

Symptoms include rapid pulse, hot, dry skin, high body temp, weakness

Has been fatal for athletes during exercise in extreme heat
Hypertension is a chronic condition characterized by high blood pressure.
Systolic pressure over 140mm Hg

Diastolic pressure over 90mm Hg

May not show symptoms

Increases a person’s risk of heart disease, stroke, kidney disease
Does high sodium intake cause hypertension?
The cause of 95% of hypertension cases is unknown

Very few people with hypertension show salt sensitivity

However, most health organizations still recommend a reduced sodium intake
Antioxidants can function in different ways
Some vitamins donate their electrons to free radicals to stabilize them

Some minerals act as cofactors with enzymes to destroy free radicals
Functions of selenium
Antioxidant; part of the glutathione peroxidase enzyme system

Production of thyroxine – a thyroid hormone
Sources of selenium
High sources include organ meats, pork, seafood, nuts, wheat, rice
What if you consume too much selenium?
Selenium toxicity (brittle hair, nails, skin rashes) can result from supplements
What if you don’t consume enough selenium?
Keshan disease – a heart disease
Kashin-Beck disease – an arthritis
Bone structure
Provides strength to support the body
Allows for flexibility
Contains about 65% minerals providing the hardness of bone
Contains 35% organic structures for strength, durability, flexibility
Collagen
fibrous protein in bone tissue
Cortical bone (compact bone):
very dense tissue making up 80% of the skeleton.
Trabecular bone (spongy bone)
scaffolding” on the inside of bones; supports cortical bone and makes up 20% of the skeleton.
Bone growth
increase in bone size; completed by age 14 in girls and age 17 in boys
Bone modeling
shaping of bone; completed by early adulthood
Bone remodeling
reshaping of bone
Bone remodeling involves:
Resorption – surface of bones is broken down
Osteoclasts
cells that erode the surface of bones
Formation of new bone by cells called osteoblasts
Osteoblasts produce the collagen-containing component of bone
Bone density
Peak bone density is reached before the age of 30

Remodeling maintains bone density during early adulthood

Density begins to decrease after age 40 because resorption exceeds new bone formation
Calcium
is the most abundant major mineral in the body.
Functions of calcium
Form and maintain bones and teeth
Assists with acid-base balance
Transmission of nerve impulses
Assist in muscle contraction
Recommended intake Calcium
RDA values are between 700 and 1,300 mg per day depending on age and gender.
Sources of calcium
Skim milk, low-fat cheese, nonfat yogurt, green leafy vegetables
What if you consume too much calcium?
Excess calcium is excreted from the body

Calcium supplements can lead to mineral imbalances
What if you don’t consume enough calcium?
Hypocalcemia (low blood calcium) can be caused by kidney disease or vitamin D deficiency

Osteoporosis
Functions of phosphorus
Critical to mineral composition of bone

Required for proper fluid balance

Component of ATP, DNA, membranes
Recommended intake
RDA for phosphorus is 700 mg/day.
Sources of phosphorus
High in protein-containing foods such as milk, meats, eggs
In processed foods as a food additive
In soft drinks as phosphoric acid
What if you consume too much phosphorus?
Excessive vitamin D supplements can cause high phosphorus levels, muscle spasms, and convulsions
What if you don’t consume enough phosphorus?
Deficiencies are rare in healthy adults
Functions of magnesium
A mineral found in bone structure

Nerve and heart function; muscle contraction
Sources of magnesium
Green leafy vegetables, whole grains, seeds, nuts, seafood, beans, some dairy products
What if you consume too much magnesium?
No toxicity from magnesium in food
Magnesium supplements can cause diarrhea, nausea, cramps, dehydration
What if you don’t consume enough magnesium?
Hypomagnesemia can result in low blood calcium and osteoporosis
Fluoride is a trace mineral.
99% of the body’s fluoride is stored in teeth and bones.
Functions of fluoride
Development and maintenance of teeth and bones

Combines with calcium and phosphorus to protect teeth from bacteria
Recommended intake flouride
RDA varies by gender and increases with age, ranging from 1-4 mg/day.
Sources of fluoride
Fluoridated dental products

Fluoridated water
What if you consume too much fluoride?
Fluorosis (excess fluoride) creates porous tooth enamel; teeth become stained and pitted
What if you don’t consume enough fluoride?
Dental caries (cavities)
Osteoporosis
Low bone mass
Deterioration of bone tissue
Fragile bones leading to bone fractures
Compaction of bone; decreased height
Shortening and hunching of the spine
Factors influencing the risk of osteoporosis include:
Age
Gender
Genetics
Nutrition
Physical activity
Age is a factor for osteoporosis because
Bone mass decreases with age
Age-related hormonal changes influence bone density
Older adults are less able to absorb vitamin D
Gender is a risk factor for osteoporosis.
80% of Americans with osteoporosis are women.
Women have lower bone density than men.
Estrogen loss in post-menopausal women causes increased bone loss.
Physical activity influences the risk for osteoporosis.
Regular exercise causes stress to bones, leading to increased bone mass.

Weight-bearing activities (walking, jogging) are especially helpful in increasing bone mass
There is no cure for osteoporosis.
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The progression of osteoporosis may be slowed by
Adequate calcium and vitamin D intake
Regular exercise
Anti-resorptive medications
Iodine is a trace mineral.
Critical for the synthesis of thyroid hormones

Thyroid hormones regulate body temperature and resting metabolic rate

Good sources: saltwater fish, shrimp, iodized salt, milk and dairy products
Excess iodine
Blocks synthesis of thyroid hormones
Thyroid tries to make more hormones
Results in goiter – enlarged thyroid
Iodine deficiency
Results in hypothyroidism and goiter
Cretinism
mental retardation from iodine deficiency during embryonic development
Chromium is a trace mineral.
Assists insulin as it transports glucose from the blood into the cells
There is very little chromium in the body
Good sources: mushrooms, prunes, dark chocolate, nuts, whole grains
Chromium deficiency inhibits glucose absorption by body cells
Manganese is a trace mineral.
Coenzyme involved in energy metabolism
Part of the antioxidant enzyme superoxide dismutase
Good sources: whole-grain foods, brown rice, pineapple, pine nuts, okra, spinach
Toxicity impairs the nervous system causing spasms and tremors
Sulfur is a major mineral.
Component of thiamin and biotin
Required for detoxification of alcohol and drugs by the liver
Found in a few amino acids
Sufficient sulfur is synthesized from the protein in our diets
Blood is the only fluid tissue in the body.
Functions:
Transport of oxygen and nutrients to cells
Removal of wastes from tissues
Erythrocytes
red blood cells for transporting oxygen through the body
Leukocytes
white blood cells of the immune system
Platelets
cell fragments that assist in blood clotting
Plasma
the fluid portion of the blood
Iron is a trace mineral.
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Functions of iron
A component of the protein hemoglobin which carries oxygen in erythrocytes
A component of myoglobin which carries oxygen in muscle cells
A coenzyme involved in energy metabolism of carbohydrates, fats, and proteins
RDA iron
RDA varies based on age and gender.
8 mg/day for adult men.
27 mg/day for pregnant women.
Sources of iron
Meat, poultry, fish, clams, oysters, enriched cereals and breads
Two types of iron are found in foods
Heme iron – found in animal based foods and more absorbable
Non-heme iron – not easily absorbed
What if you consume too much iron?
Iron overdose is the most common cause of poisoning deaths in children
Toxicity symptoms: nausea, vomiting, diarrhea, dizziness, confusion
Increased risk for heart attack
Liver and heart damage in hemochromatosis
Constipation
What if you don’t consume enough iron?
Iron deficiency is the most common nutrient deficiency in the world
High risk people include infants, young children, preadolescent girls, premenopausal women, and pregnant women
There are three stages of iron deficiency
Iron-deficient anemia
Iron deficiency results in small red blood cells that do not carry enough hemoglobin
Symptoms are fatigue, pale skin, impaired work performance, depressed immune function, impaired memory
Zinc is a trace mineral.
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Functions of zinc
Coenzyme for hemoglobin production
Part of superoxide dismutase antioxidant enzyme system
Development and function of immune system
Sources of zinc
Red meats, some seafood, whole grains, enriched grains and cereals
What if you consume too much zinc?
Toxicity can occur from supplements
Symptoms are intestinal pain, cramps, nausea, vomiting, loss of appetite
What if you don’t consume enough zinc?
Deficiencies are uncommon in the US
Symptoms are growth retardation, diarrhea, delayed sexual maturation
Functions of copper
Coenzyme for energy metabolism, and for collagen production
Part of superoxide dismutase antioxidant enzyme system
Required for iron transport
Sources of copper
Organ meats, seafood, nuts, seeds, whole grain foods
What if you consume too much copper?
Toxicity in not well studied in humans
Symptoms are intestinal pain, cramps, nausea, vomiting, liver damage
What if you don’t consume enough copper?
Copper deficiency is rare
Symptoms are anemia, reduced white blood cells, osteoporosis in children