Migraine

Front 1

________ are serotonin receptor agonists

Back 1

Triptans

Front 2

Triptans can cause _________ of cranial blood vessels (reason they are effective for headaches)

Back 2

Vasoconstriction

Front 3

The best way to treat menstrual-related migraines?

Back 3

Hormone therapy

Front 4

Components of Excedrin Migraine?

Back 4

ASA + APAP + Caffeine

Front 5

If a patient has migraines > _____ times per month, or has severe symptoms, prophylaxis should be used

Back 5

> 1 per month

Front 6

All prophylactic agents can decrease migraine frequency by up to?

Back 6

50%

Front 7

6 triggers for migraines

Back 7

Hormonal changes
Food/alcohol
Stress
Sensory stimuli
Changes in sleep/wake pattern
Changes in environment

Front 8

8 natural products that may be helpful for migraines?

Back 8

Feverfew, willow bark, butterbur, gurana, fish oils, magnesium, CoQ10, riboflavin

Front 9

Naratriptan

Back 9

Amerge

Front 10

Almotriptan

Back 10

Axert

Front 11

Frovatriptan

Back 11

Frova

Front 12

Sumatriptan

Back 12

Imitrex

Front 13

Rizatriptan

Back 13

Maxalt

Front 14

Eletriptan

Back 14

Relpax

Front 15

Zolmitriptan

Back 15

Zomig

Front 16

Sumatriptan + Naproxen

Back 16

Treximet

Front 17

Max doses per day for Treximet?

Back 17

2 tablets per 24 hours

Front 18

3 dosage forms for sumatriptan

Back 18

Intranasal, PO, Injectable (SQ)

Front 19

3 dosage forms for Zomig?

Back 19

Oral tablet, ODT, Nasal spray

Front 20

_________ can include pressure in chest or heaviness/pressure in neck region; this usually goes away after administration

Back 20

"Triptan sensations"

Front 21

2 longest acting triptans?

Back 21

Frovatriptan (Frova)
Naratriptan (Amerge)

Front 22

ODT triptans are best for migraines associated with?

Back 22

Vomiting, Dysphagia

Front 23

Triptans are contraindicated in patients with?

Back 23

CV disease

Front 24

________ is available as a needleless injection

Back 24

Sumavel DosePro (sumatriptan)

Front 25

In one study, _______ 40 mg was more effective than ______ 100 mg in relieving pain

Back 25

Eletriptan; Sumatriptan

Front 26

How to take ODT triptans

Back 26

Allow to completely dissolve on tongue, do not use water

Front 27

All triptans can be repeated in 2 hours if needed EXCEPT?

Back 27

Naratriptan (Amerge)-- Repeat in 4 hours if needed

Front 28

Which 3 triptans are contraindicated with MAOIs?

Back 28

Imitrex
Maxalt
Zomig

Front 29

__________ is a triptan contraindicated with strong 3A4 inhibitors?

Back 29

Eletriptan (Relpax)

Front 30

Which formulations of migraine medications have fastest onset?

Back 30

Injectables and Nasal Sprays

Front 31

How many doses come in Zomig nasal spray?

Back 31

1 (do not prime it,you will waste the dose)

Front 32

Of the OTC items, which is a poor option for migraines due to increased incidence of nausea?

Back 32

Aspirin

Front 33

Components of FioriCET? (Schedule?)

Back 33

Butalbital/APAP/Caffeine (C3)

Front 34

ASA + Butalbital + Caffeine

Back 34

FioriNAL

Front 35

Fiorinal and Fioricet are both available with?

Back 35

Codeine

Front 36

______ is a C4 intranasal spray that delivers fast and effective migraine relief

Back 36

Butorphanol (Stadol)

Front 37

Onset of Stadol?

Back 37

15 minutes

Front 38

Ergotamine products are pregnancy category?

Back 38

X

Front 39

Ergotamine side effects include?

Back 39

N/V
Muscle pain
Tingling in periphery
Angina-like chest pain

Front 40

Name 2 ergoloid mesylates?

Back 40

Ergomar, Ergostat

Front 41

________ is the brand name for ergotamine/caffine

Back 41

Cafergot

Front 42

A full trial for migraine prophylaxis is at least?

Back 42

2-6 months therapy

Front 43

Non-triptan commonly used for migraine prophylaxis due to its favorable side effect profile and weight loss properties

Back 43

Topamax

Front 44

First line therapies for migraine prophylaxis include?

Back 44

Propranolol
Timolol
Amitriptyline
Divalproex
Sodium Valproate
Topiramate

Front 45

2 most commonly used beta-blockers for migraine prophylaxis?

Back 45

Propranolol
Timolol

Front 46

TCA most commonly used for migraine prophylaxis?

Back 46

Amitriptyline (Elavil)

Front 47

Avoid _______ (anticonvulsant used for migraine prophylaxis) in women of childbearing age

Back 47

Divalproex

Front 48

To prevent medication-overuse headaches, it is important to educate patients to limit acute meds to?

Back 48

Max of 2-3 times per week

Front 49

Triptan with longest duration of action?

Back 49

Frovatriptan

Front 50

Where to inject Imitrex STATdose?

Back 50

SQ in upper-outer arm

Front 51

3 triptans contraindicated with MAOIs?

Back 51

Imitrex
Maxalt
Zomig

Front 52

Best drug to use for migraines in a patient with liver failure?

Back 52

Topamax

Front 53

Max # of Imitrex injections in 24 hours?

Back 53

2

Front 54

Best option for migraine treatment in pregnancy?

Back 54

Acetaminophen