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147 Cards in this Set

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The Heart

- Approx size of fist


- 250-300 grams


- 7000-9000L of blood/day


- Location Mediastinum

Interesting facts like size, weight, volume pumped/day, location.

Point of Maximal impulse

- Apex rotates forward with systole


- Gently beating against chest wall


- Produce a pulsation

Location within the heart


Rhythm


Pulsation..

Pericardium

Protective double walled sac around the heart


- Parietal (outer fibrous layer)


- Visceral/Epicardium (Lines the surface of heart)

Sac with double layers want’s to protect

Pericardium function

Protects and anchors the heart


Prevents overfilling of the heart with blood


Separated by two layers


25-50mL between Called pericardial fluid


Gives the heart friction less resistance

Pericardial effusion

Small accumulation


Too little pericardial fluid

Too little or too less


Pericardial fluid

Pericardial tamponade

- Large accumulation of pre-cardio fluid


- Reduced CO

Cardiovascular collapse

7 Layers of the heart

- Fibrous pericardium


- Partial layer of serous pericardium


- Pericardial cavity


- Visceral layer of serous pericardium (epicardium)


- myocardium


- Endocardium


- Heart chamber

Starting from the sac to the chambers

What is the most common organelle in Cardiac muscle?

Mitochondria


Gives cells high resistance to fatigue

Accounts to 25% of the volume of cardiac cells

In what are the 4 Heart chambers

2 ( Atria left and right )


- receives blood


2 ( Ventricles left and right )


- pumps out

- receive incoming blood


- Pump blood out

What separates the the heart in half?

Atria - inreratrial septum


Ventricles - interventricular Septum

Both atrias and ventricles have different things separating them in half

What are the veins that enter the right atria?

Superior vena cava,


- blood returns superior to diaphragm


Inferior vena cava


- blood returns inferior to diaphragm


Coronary sinus


- blood from myocardium

Veins the receive deoxygenated blood

How many pulmonary veins enter the left atria and where can they be seen?

- 4 pulmonary veins


- seen in posterior of heart

Pulmonary veins are moving oxygenated blood into the heart from the lungs

What is the Auricle?

-Small expandible muscular pouch in upper portion of atrium


-Purpose: increase blood capacity of atrium (Atrial kick)

What are the four valves of the heart?

- Two AV valves —> between atria and ventricles


- Tricuspid —> right atrium to right ventricle


- Mitral/Bicuspid —> left atrium to left ventricle

What are Chordae Tendineae?

Chordae Tendineae are strong fibrous connection Between the valve, leaflets on to the ventricular side, and prevent the costs from swinging back into atrial cavity during system


(They pull the walls of the ventricles inward during contraction)

What is AV valve function?

-ventricles contract


-forces blood against AV valve cusps


-AV valves close


-Papillary muscles contract


-Chordae tendineae tighten

What do the two semi lunar valves do? What are they?

- Allow ejection of blood from heart into arteries, prevents Backflow of blood into ventricles


-Right semilunar (pulmonary valve) it connects right ventricle to pulmonary artery


-left semilunar (aortic valve) it connects left ventricle to aorta

When do semi lunar valves open? (SL valves)

-Ventricles contract


-Intraventricular pressure falls


-Blood flows back from arteries


-Fills cup of semilunar valve forcing close

When do the semilunar valves close?

-ventricles relax


-Intraventricular pressure falls


-blood flows back from arteries


-fills cup of semilunar valve forcing close

When do valves open/close?

-when vest recalls are contracting and Intraventricular Pressure rises above aortic pressure= valve open


-when ventricles relax the back flowing blood = close valve

What is the pathway of blood through the heart?

Right atrium —> tricuspid valve —> right ventricle—>pulmonary semilunar valves —> pulmonary arteries —> lungs into pulmonary veins —> left atrium —> bicuspid valve —> left ventricle —> aortic semi lunar valve —> aorta —> systemic circulation

Starts in the right atrium, and ends out of the aorta

What is collateral circulation?

Anastomoses (numerous connections) between arterioles ensures blood delivery to heart, even if major vessels are occluded

Where do Coronary veins travel?

Along side, arteries and drain into right atrium, near base of inferior vena cava

What is collateral circulation?

Anastomoses (numerous connections) between arterioles ensures blood delivery to heart, even if major vessels are occluded

Coronary circulation

- coronary arteries fill, ventricles are relaxed


-aorta recoils (elastic rebound)


-pushes blood systemically and backward into the coronary arteries

Where does the coronary circulation branch off?

Just above the aortic valve

Where does the coronary circulation branch off?

Just above the aortic valve

Where is the right coronary artery? (RCA)

In Sulcus between right atrium and right ventricle

Where does the marginal arteries supply?

Surface of right ventricle

What does the left coronary artery (LCA) subdivide into?

left anterior descending (LAD)


- Anterior and lateral left ventricle


- Anterior 2/3 interventricular septum


- Most of right, and left bundle branch


Circumflex coronary artery (CX)


-left atrium


-inferior and lateral left ventricle


-SA node and AV bundle

Where do arteries in Coronary circulation travel?

Over the surface of the heart, and come out into myocardium

How much on the endocardium can receive 02 from cardiac chambers?

1/10 mm (to put in perspective, 1/10 mm is 100 µm or micrometers which is the width of a human hair)

What happened through the process of Arterogenesis

Anastomotic network starts to increase in size towards the area of reduced blood flow

What happened through the process of Arterogenesis

Anastomotic network starts to increase in size towards the area of reduced blood flow

When does Arterogenesis occur?

When Mechanoreceptors detect stress within the endothelium

What does the corners sinus collect?

Majority of cardiac venous blood


Opens into base of inferior vena cava

Where does the corner is sinus empty?

Right atrium

What is the corner sinus?

The coronary sinus Is a large Venus structure located on the posterior aspect of the left atrium


The function of the corner sinus is to drain the venous blood from the majority of the heart

What is automaticity?

Stimulated by nerves and self excusable (heart muscle)

What percentage of muscle contraction does mitochondria account for? (Cardiac)

20-25%

What percent of muscle contraction does skeletal account for (cardiac)

2%


High resistance to fatigue

What percent of muscle contraction does skeletal account for (cardiac)

2%


High resistance to fatigue

How long is the cardiac cycle?

0.8 seconds total


Systole (contracts) = 0.1sec


Diastole (relax) =0.7 sec

Both under a second

What percent of muscle contraction does skeletal account for (cardiac)

2%


High resistance to fatigue

How long is the cardiac cycle?

0.8 seconds total


Systole (contracts) = 0.1sec


Diastole (relax) =0.7 sec

Both under a second

What is Systole?

- Contraction on heart muscles


- Blood pumped into arteries

What percent of muscle contraction does skeletal account for (cardiac)

2%


High resistance to fatigue

How long is the cardiac cycle?

0.8 seconds total


Systole (contracts) = 0.1sec


Diastole (relax) =0.7 sec

Both under a second

What is Systole?

- Contraction on heart muscles


- Blood pumped into arteries

What is diastole?

- Relaxation of heart muscle


- Heart fills with blood

What percent of muscle contraction does skeletal account for (cardiac)

2%


High resistance to fatigue

How long is the cardiac cycle?

0.8 seconds total


Systole (contracts) = 0.1sec


Diastole (relax) =0.7 sec

Both under a second

What is Systole?

- Contraction on heart muscles


- Blood pumped into arteries

What is diastole?

- Relaxation of heart muscle


- Heart fills with blood

What are the steps of the cardiac cycle ?/5

-1. Atrial Systole


- 2. Isovolumetric ventricular contraction


- 3. Ejection


- 4. Isovolumetric ventricular relaxation


- 5. Passive ventricular filling

What percent of muscle contraction does skeletal account for (cardiac)

2%


High resistance to fatigue

How long is the cardiac cycle?

0.8 seconds total


Systole (contracts) = 0.1sec


Diastole (relax) =0.7 sec

Both under a second

What is Systole?

- Contraction on heart muscles


- Blood pumped into arteries

What is diastole?

- Relaxation of heart muscle


- Heart fills with blood

What are the steps of the cardiac cycle ?/5

-1. Atrial Systole


- 2. Isovolumetric ventricular contraction


- 3. Ejection


- 4. Isovolumetric ventricular relaxation


- 5. Passive ventricular filling

What is atrial Systole?

-Low heart, blood pressure


- Blood enters from pulmonary and systemic circulation


- flows into ventricles (80% passive, 20% atrial contraction)


KICK


-AV valves are open


- SL valves are closed

KICK

What is Isovolumetric ventricular Contraction

- Ventricles close


- Pressure in the ventricles increase until pressure is more than aorta/pulmonary trunks

Ejection and what is it?

Opens SL valves

What is Isovolumetric ventricular relaxation?

- Ventricles, relax, and pressure drops


- Backflow of blood in aorta and pulmonary trunk close SL valves


- Dicrotic notch


- Ventricles are closed


What is Isovolumetric ventricular relaxation?

- Ventricles, relax, and pressure drops


- Backflow of blood in aorta and pulmonary trunk close SL valves


- Dicrotic notch


- Ventricles are closed


What is Passive ventricular filling?

- Pressure in the ventricles lower than atria


- AV valves close


- Cycle starts again

What is Dicrotic Notch?

Brief rise, in aortic pressure caused by backflow of blood rebounding off SL valves

What is Dicrotic Notch?

Brief rise, in aortic pressure caused by backflow of blood rebounding off SL valves

What is the pressure in Right atrium?

0-2mmHg

What is Dicrotic Notch?

Brief rise, in aortic pressure caused by backflow of blood rebounding off SL valves

What is the pressure in Right atrium?

0-2mmHg

What is the pressure in the right ventricle?

25 systolic mmHg

What is the pressure in the pulmonary arteries?

25 systolic mmHg

What is the pressure in the pulmonary arteries?

25 systolic mmHg

What is the pressure in the left atrium?

8-10mmHg

What is the pressure in the pulmonary arteries?

25 systolic mmHg

What is the pressure in the left atrium?

8-10mmHg

What is the pressure in the left ventricle?

120 systole mmHg

What is the pressure in the pulmonary arteries?

25 systolic mmHg

What is the pressure in the left atrium?

8-10mmHg

What is the pressure in the left ventricle?

120 systole mmHg

What is the pressure in the aorta?

120 systole mmHg

What is the pressure in the pulmonary arteries?

25 systolic mmHg

What is the pressure in the left atrium?

8-10mmHg

What is the pressure in the left ventricle?

120 systole mmHg

What is the pressure in the aorta?

120 systole mmHg

What is cardiac output, (CO?)

The amount of blood pumped by each ventricle in one minute


Best indicator of adequate blood flow to peripheral tissue


Product of HR x SV = CO

What is the pressure in the pulmonary arteries?

25 systolic mmHg

What is the pressure in the left atrium?

8-10mmHg

What is the pressure in the left ventricle?

120 systole mmHg

What is the pressure in the aorta?

120 systole mmHg

What is cardiac output, (CO?)

The amount of blood pumped by each ventricle in one minute


Best indicator of adequate blood flow to peripheral tissue


Product of HR x SV = CO

What is cardiac reserve?

The difference between resting and maximal O2

What is the pressure in the pulmonary arteries?

25 systolic mmHg

What is the pressure in the left ventricle?

120 systole mmHg

What is the pressure in the aorta?

120 systole mmHg

What is cardiac output, (CO?)

The amount of blood pumped by each ventricle in one minute


Best indicator of adequate blood flow to peripheral tissue


Product of HR x SV = CO

What is cardiac reserve?

The difference between resting and maximal O2

What is the average stroke volume?

80mL

What is the pressure in the pulmonary arteries?

25 systolic mmHg

What is the pressure in the left atrium?

8-10mmHg

What is the pressure in the left ventricle?

120 systole mmHg

What is the pressure in the aorta?

120 systole mmHg

What is cardiac output, (CO?)

The amount of blood pumped by each ventricle in one minute


Best indicator of adequate blood flow to peripheral tissue


Product of HR x SV = CO

What is cardiac reserve?

The difference between resting and maximal O2

What is the average stroke volume?

80mL

What is the ejection fraction? What is normal?

The percentage of blood pumped out of ventricle each contraction


Measure of ventricular function


Normal = 50% and 65%

What is the pressure in the pulmonary arteries?

25 systolic mmHg

What is the pressure in the left atrium?

8-10mmHg

What is the pressure in the left ventricle?

120 systole mmHg

What is the pressure in the aorta?

120 systole mmHg

What is cardiac output, (CO?)

The amount of blood pumped by each ventricle in one minute


Best indicator of adequate blood flow to peripheral tissue


Product of HR x SV = CO

What is cardiac reserve?

The difference between resting and maximal O2

What is the average stroke volume?

80mL

What is the ejection fraction? What is normal?

The percentage of blood pumped out of ventricle each contraction


Measure of ventricular function


Normal = 50% and 65%

What is stroke volume?

End Diastolic volume (EDV) minus End Systolic Volume (ESV)


(EDV) - (ESV) = (SV)

What is EDV?

Amount of blood collected in a ventricle during diastole

What is EDV?

Amount of blood collected in a ventricle during diastole

What is ESV?

Amount of blood remaining in a ventricle after contraction

What is EDV?

Amount of blood collected in a ventricle during diastole

What is ESV?

Amount of blood remaining in a ventricle after contraction

What factors affect the stroke, volume?

Venous return


Preload


Contractility


Afterload

What is EDV?

Amount of blood collected in a ventricle during diastole

What is ESV?

Amount of blood remaining in a ventricle after contraction

What factors affect the stroke, volume?

Venous return


Preload


Contractility


Afterload

What is EDV?

Amount of blood collected in a ventricle during diastole

What is ESV?

Amount of blood remaining in a ventricle after contraction

What factors affect the stroke, volume?

Venous return


Preload


Contractility


Afterload

What is venous return?

Amount of venous blood returned to heart

What is EDV?

Amount of blood collected in a ventricle during diastole

What is ESV?

Amount of blood remaining in a ventricle after contraction

What factors affect the stroke, volume?

Venous return


Preload


Contractility


Afterload

What is venous return?

Amount of venous blood returned to heart

What is preload?

Amounts ventricles are stretched, be contained blood


Or


The pressure under which the ventricle fills

What is a critical factor controlling SV?

Pre-load of cardiac muscle cells before they contract

What is a critical factor controlling SV?

Pre-load of cardiac muscle cells before they contract

SV increases when? or decreases when?

- Slow HP, & exercise increases venous, return to the heart equals increase SV


- Blood loss and rapid HB equals decreased SV


Hb = Haemoglobin

What is a critical factor controlling SV?

Pre-load of cardiac muscle cells before they contract

SV increases when? or decreases when?

- Slow HP, & exercise increases venous, return to the heart equals increase SV


- Blood loss and rapid HB equals decreased SV


Hb = Haemoglobin

What is the frank starling law?

- More blood in, more blood out


- The greater the volume of blood in the ventricle stronger the contraction


- Increased filling time and blood volume equals increased. SV

What is contractility?

The increase in contractile strength, independent of stretch, and EDV

What is contractility?

The increase in contractile strength, independent of stretch, and EDV

Where does an increase in contractility come from?

- Increased, sympathetic stimuli


- Certain hormones


- Ca2+ and some drugs

What is contractility?

The increase in contractile strength, independent of stretch, and EDV

Where does an increase in contractility come from?

- Increased, sympathetic stimuli


- Certain hormones


- Ca2+ and some drugs

What does a decrease in contractility come from?

- Acidosis


- Increased extracurricular K+


- Beta blockers and calcium channel blockers


(AKA: Cardiac Drugs)

What are the signs and symptoms of decreased CO?

Acute changes in BP


Acute changes in mental status


Cold, clammy skin


Colour changes in skin and mucous membranes


Crackles/rales


Dyspnea(shortness of breath)


Dysrhythmias(irregular heartbeat)


Fatigue


Orthopnea


Restlessness