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18 Cards in this Set
- Front
- Back
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The signal for newly replicated eukaryotic replication origins that is similar to hemimethylated DNA in E.coli is: |
Phosphorylated orc |
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Telomerase makes a template for DNA polymerase by: |
extending the 3' ends of the chromosome |
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The most common causes of mutations due to damage to DNA are caused by: |
Hydrolysis reactions |
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DNA which contains a transversion mutation is most likely to be repaired by a mechanism that is most similar to: |
Nucleotide excision repair |
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The deamination of adenosine to hypoxanthine is most likely to be repaired by: |
base excision repair |
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A number of human genetic diseases cause hypersensitivity to UV irridiation. Most of the mutated genes in these disorders are in the genes involved in: |
nucleotide excision repair |
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Ionizing radiation often causes mutations because it causes DNA damage that is repaired by: |
Non-homologous end joining |
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Homologous recombination in bacteria is most often used to repair: |
broken replication forks |
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RecA binds: |
Single stranded DNA with a 3' end |
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Given what you know about RecA from class you would expect a E.coli with a deletion mutant in RecA to be hypersensitive to: |
Ionizing radiation |
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A translesion polymerase is used to replicate a DNA that has a pyrimidine dimer between C and T, the translesion polymerase will most likely add: |
Cannot tell from information given |
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Most bacterial transposons are: |
DNA only transposons |
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loxP sites used to delete DNA using cre recombinase are: |
direct repeats |
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The best way to determine which sequences in a genome are likely to encode protein is to find: |
sequences that are conserved in different organisms |
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RNA |
is not always single stranded |
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When RNA polymerase is transcribing is moves: |
3' to 5' relative to the template strand. 5' to 3' relative to the non-template strand |
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Which of the following are unique to transcription that is not observed in replication: |
Abortive initiation |
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Which of the following do/does NOT bind to DNA? |
Mediator |
