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6 Cards in this Set

  • Front
  • Back
What is Giardia?
It exists in 2 forms; as a cyst and trophozoite.
It is estimated that 5% of US adults harbor this organism, asymptomatically.
Outbreaks come from sewage contaminated water and from rodents and beavers.
What is the pathogenesis of Giardia?
After ingestion of the cyst, Giardia converts to the trophozoite and adheres to the small intestinal wall. It coats the small intestine, interfering with intestinal fat absorption. Blood is not usually seen, due to the inability of the Giardia to invade the intestinal wall.
What is Cryptosporidium?
Animals and humans are equally affected. App. 25% of americans show serologic evidence of previous infection. It causes outbreaks of diarrhea.
Cryptosporidium is ingested as a round oocyst that has 4 motile sporozoites. TRUE/FALSE
TRUE. Its life cycle occurs within the intestinal epithelial cells and it causes diarrhea and pain.
Is there a treatment for Cryptosporidium?
No effective therapy is known. Azithromycin is being investigated as a possible treatment regimen.
What is Isospora and Microsporidia?
These organisms cause a severe diarrhea in immunocompromised individuals. It is transmitted via the fecal oral route.
The combination of trimethoprim with sulfamethoxazole is effective against Isospora, while albendazole can treat microspora.