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5 Cards in this Set
- Front
- Back
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What disorder does H. pylori most commonly cause?
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90% of patients with duodenal ulcers(chronic non-steroidal anti inflammatory drug use accounts for the other 10%.
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How can H. pylori be biochemically characterized?
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Catalase positive, oxidase positive, and urease positive. Urease, an important pathogenic factor, produces ammonia and bicarbonate that neutralizes gastric acids.
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How is H. pylori diagnosed?
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Invasive(endoscopy) or non-invasive(serology or patients drink C14-labeled urea which is hydrolyzed to ammonia and labeled CO2 that is detected in their breath.
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What are the long term consequences of H. pylori infection?
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Chronic gastritis, gastric adenocarcinoma, and mucosa associated lymphoid tumor(MALT), type B lymphoma
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What is the combination of medications used to treat H. pylori infection?
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Triple therapy, originally included bismuth salts, metronidazole, and either ampicillin or tetracycline. The current regimen of choice is a proton pump inhibitor, amoxicillin, and clarithromycin.
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