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5 Cards in this Set
- Front
- Back
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How does C. tetani cause tetanus?
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C. tetani acquired from traumatic wound releases tetanus toxin(exotoxin) which blocks the release of inhibitory neurotransmitter glycine and GABA fron Renshaw cells in the spinal cord.
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What are the symptoms of tetanus?
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Spastic paralysis due to prolonged muscle contracture results from lack of inhibition(loss of glycine) resulting in dysphagia(early), trismus(lockjaw), risus sardonicus(grimace) and respiratory failure.
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How is tetanus treated?
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Antitoxin, antibiotics, sedatives and muscle relaxants to prevent spasms, and debridement of wounds.
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What is the tetanus vaccine made of?
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Formalin inactivated tetanus toxoid.
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What is in a diphtheria, tetanus and pertussis(DTaP) childhood vaccine?
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Diptheria toxin, tetanus toxoid and acellular pertussis antigen.
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