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5 Cards in this Set

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  • Back
How does C. tetani cause tetanus?
C. tetani acquired from traumatic wound releases tetanus toxin(exotoxin) which blocks the release of inhibitory neurotransmitter glycine and GABA fron Renshaw cells in the spinal cord.
What are the symptoms of tetanus?
Spastic paralysis due to prolonged muscle contracture results from lack of inhibition(loss of glycine) resulting in dysphagia(early), trismus(lockjaw), risus sardonicus(grimace) and respiratory failure.
How is tetanus treated?
Antitoxin, antibiotics, sedatives and muscle relaxants to prevent spasms, and debridement of wounds.
What is the tetanus vaccine made of?
Formalin inactivated tetanus toxoid.
What is in a diphtheria, tetanus and pertussis(DTaP) childhood vaccine?
Diptheria toxin, tetanus toxoid and acellular pertussis antigen.