Microreview147(Hpv)

Front 1

What is the most common STD in the US?

Back 1

Human papillomavirus. Chlamydia is only the most common bacterial STD.

Front 2

HPV strains 16 and 18 are thought to cause cervical cancer by the inhibition of what tumor suppressor genes?

Back 2

HPV 16 creates protein product E6, which inhibits p53;
HPV 18 makes protein product E7, which inhibits the retinoblastoma(Rb) tumor suppressor gene.

Front 3

What strains of HPV cause anogenital warts(condyloma acuminatum)?

Back 3

HPV strains 6 and 11.

Front 4

A pap smear from a patient infected with HPV would show what characteristic cytopathology?

Back 4

Koilocytic cells or cells that show perinuclear cytoplasmic vacuolization with nuclear enlargement.

Front 5

What rare cancer is caused by Schistosoma haematobium?

Back 5

Squamous cell carcinoma of the bladder usually in patients from Egypt. Most bladder cancers are transitional cell sarcomas.

Front 6

What species of bacteria causes a painful genital lesion similar to the lesion seen in primary syphilis?

Back 6

Haemophilus ducreyi