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9 Cards in this Set

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What is subunit of microfilaments?

Actin monomers

Structure of microfilaments?

Double helix of actin monomers


Smallest in diameter of cytoskeleton


Thinnest most flexible.


Also polar and dynamic



Polymerisation/depolymerisation of microfilaments?

1.When ATP binds to actin = POLYMERISATION.


2.ATP hydrolysed to ADP = DEPOLYMERISATION.

Where are microfilaments found?

Throughout cytoplasm & highly concentrated in cell cortex.

Why are mocrofilaments highly concentrated in cell cortex?

To help reinforce cell membrane and give mechanical strength in terms of structure and organisation

Do microfilaments involve cell crawling?

Depends on actin microfilaments. Not all cells are stationary some move or crawl.


Increased actin polymerisation allows cell to move in certain directions.

Actin

Dynamic - control behaviour of actin filaments.


Microfilaments found in Cross linked bundles, gel-like bundles & contractile bundle through cross-link with different proteins.


E.g microvillus

Microfilaments & mitosis

In mitosis, separation of cytoplasm for 2 daughter cells occurs where each has their own plasma membrane.


The ring of actin filaments action/contraction of these myosin allow separation.

Myosin

Motor protein, which allows sliding of microfilaments = contraction but requires ATP.