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6 Cards in this Set
- Front
- Back
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What is the most salient symptom of the Mumps?
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Parotitis. Swelling of the Parotid gland. Other organs may be involved as well. The testes, ovaries, thyroid gland, pancreas, meninges, heart and the kidney.
Immunity is generally permanent. |
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In 20-30% of young adult males where does the mumps infection localize?
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In the epididymis and the testes, usually on one side only. Occasionally, partial atrophy of the affected testicle is seen.
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In mumps pancreatitis, the virus replicates in beta cells and pancreatic epithelial cells. TRUE/FALSE
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TRUE.
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What is the causative agent of the Mumps?
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It is caused by an envelope single stranded RNA virus from the genus Paramyxovirus.(Paramyxoviridae). Other members of this family that infect humans are Morbillovirus)measles) and the respiratory syncytial virus.
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What is the pathogenesis of the Mumps?
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A virus infected cell is modified by the insertion of the HN spikes into its cell membrane. These spikes immediately bind an uninfected neighboring cell and in the presence of F spikes the two cells permanently fuse.
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How is the mumps diagnosed visually?
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A chain reaction of multiple cell fusions then produces a syncytium with cytoplasmic inclusion bodies, which is a diagnostically useful cytopathic effect. This effect is typical of paramyxoviridae.
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