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6 Cards in this Set

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What is the most salient symptom of the Mumps?
Parotitis. Swelling of the Parotid gland. Other organs may be involved as well. The testes, ovaries, thyroid gland, pancreas, meninges, heart and the kidney.
Immunity is generally permanent.
In 20-30% of young adult males where does the mumps infection localize?
In the epididymis and the testes, usually on one side only. Occasionally, partial atrophy of the affected testicle is seen.
In mumps pancreatitis, the virus replicates in beta cells and pancreatic epithelial cells. TRUE/FALSE
TRUE.
What is the causative agent of the Mumps?
It is caused by an envelope single stranded RNA virus from the genus Paramyxovirus.(Paramyxoviridae). Other members of this family that infect humans are Morbillovirus)measles) and the respiratory syncytial virus.
What is the pathogenesis of the Mumps?
A virus infected cell is modified by the insertion of the HN spikes into its cell membrane. These spikes immediately bind an uninfected neighboring cell and in the presence of F spikes the two cells permanently fuse.
How is the mumps diagnosed visually?
A chain reaction of multiple cell fusions then produces a syncytium with cytoplasmic inclusion bodies, which is a diagnostically useful cytopathic effect. This effect is typical of paramyxoviridae.