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8 Cards in this Set
- Front
- Back
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Class I MHC is composed of a heavy chain noncovalently bound to a _________.
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Beta 2 Microglobulin
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Where are MHC I proteins found?
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On the surface of virtually all nucleated cells.
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Where are MHC II proteins found?
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On macrohages, B cells, dendritic cells and langerhans cells.
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This type of graft rejection sees a reduction in circulation and mononuclear cell infiltration in 11-14 days. Leads to necrosis.
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Acute Allograft Rejection - T cell mediated reaction is the main cause of rejection
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Which class of MHC plays the major role in graft rejection:
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MHC II
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The main pathogenic finding in this type of allograft rejection is atherosclerosis of the vascular endothelium.
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Chronic rejection- incompatability of Minor MHC antigens
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Hyperacute rejection is due to the reaction of preformed _______ antibodies.
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Anti-ABO
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This reaction occurs when immunocompetent transplant cells attack an immuno-compromised host.
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Graft vs. Host Disease
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